Tag: Temperature Control

Difficulty in ensuring consistent capsule drying times.

April 15, 2025 Admin

Difficulty in ensuring consistent capsule drying times. Difficulty in Ensuring Consistent Capsule Drying Times Introduction: The pharmaceutical industry heavily relies on solid oral dosage forms like capsules due to their convenience, stability, and patient compliance. However, achieving consistent drying times for capsules, particularly hard and soft gelatin types, is critical yet challenging. The drying process…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent performance of dehumidification systems.

April 12, 2025 Admin

Problems with ensuring consistent performance of dehumidification systems. Problems with ensuring consistent performance of dehumidification systems. Introduction: In the manufacturing of solid oral dosage forms, particularly capsules, maintaining the right environmental conditions is crucial. Dehumidification systems play a significant role in ensuring that humidity levels are optimal for processes such as mixing, encapsulation, and storage….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in capsule drying validation for high-oil formulations.

April 12, 2025 Admin

Poor reproducibility in capsule drying validation for high-oil formulations. Poor reproducibility in capsule drying validation for high-oil formulations. Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms, such as capsules, is paramount. Among the various challenges faced during capsule production, drying validation in high-oil formulations stands out due to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining proper storage conditions for packaging materials.

April 9, 2025 Admin

Difficulty in maintaining proper storage conditions for packaging materials. Difficulty in Maintaining Proper Storage Conditions for Packaging Materials Introduction: In the pharmaceutical industry, maintaining the integrity and efficacy of products is paramount. Packaging materials, particularly for solid oral dosage forms like capsules, play a critical role in protecting the product from environmental factors and ensuring…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate validation of capsule storage and handling procedures.

April 7, 2025 Admin

Inadequate validation of capsule storage and handling procedures. Inadequate Validation of Capsule Storage and Handling Procedures Introduction: In the pharmaceutical industry, the storage and handling of capsules are critical to ensuring their efficacy and safety. Capsules, whether hard or soft gelatin, are delicate and require specific environmental conditions to maintain their integrity and therapeutic value….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Challenges in Handling Soft Gel Tablets During Packaging

March 22, 2025 Admin

Resolving Challenges in Handling Soft Gel Tablets During Packaging Resolving Challenges in Handling Soft Gel Tablets During Packaging Introduction: Soft gel tablets, often referred to as soft gelatin capsules, are a popular dosage form in the pharmaceutical industry, valued for their ease of swallowing, ability to mask unpleasant tastes, and capability to deliver liquid or…

Solid Dosage form, Tablets

Addressing Failures in Temperature Uniformity for Steam Quality Testing

March 22, 2025 Admin

Addressing Failures in Temperature Uniformity for Steam Quality Testing Addressing Failures in Temperature Uniformity for Steam Quality Testing Introduction: In the pharmaceutical industry, ensuring the sterility of products is paramount, and autoclaves play a critical role in this process. Steam quality testing, particularly temperature uniformity, is a vital component in validating the efficacy of the…

Solid Dosage form, Tablets

Preventing Cracking in Coated Tablets Due to Temperature Fluctuations

March 20, 2025 Admin

Preventing Cracking in Coated Tablets Due to Temperature Fluctuations Preventing Cracking in Coated Tablets Due to Temperature Fluctuations Introduction: In the pharmaceutical industry, the integrity of coated tablets is crucial for ensuring their efficacy and stability. Coated tablets are designed to provide a protective layer that can enhance the product’s shelf life, mask unpleasant tastes,…

Solid Dosage form, Tablets

Ensuring Adequacy of Humidity Control Systems for Sugar-Coated Tablet Areas

March 18, 2025 Admin

Ensuring Adequacy of Humidity Control Systems for Sugar-Coated Tablet Areas Ensuring Adequacy of Humidity Control Systems for Sugar-Coated Tablet Areas Introduction: In the pharmaceutical industry, maintaining precise environmental conditions is crucial for the manufacturing of high-quality products. Specifically, the production of sugar-coated tablets requires stringent humidity control to ensure the integrity and efficacy of the…

Solid Dosage form, Tablets

Difficulty in maintaining accurate logs for temperature and humidity controls.

March 17, 2025 Admin

Difficulty in maintaining accurate logs for temperature and humidity controls. Difficulty in Maintaining Accurate Logs for Temperature and Humidity Controls Introduction: In the pharmaceutical industry, maintaining precise environmental controls is crucial, especially for solid oral dosage forms like capsules. Both hard and soft gelatin capsules are sensitive to temperature and humidity fluctuations, which can affect…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating gelatin mixing tanks for uniform temperature control.

March 14, 2025 Admin

Challenges in validating gelatin mixing tanks for uniform temperature control. Challenges in validating gelatin mixing tanks for uniform temperature control. Introduction: In the pharmaceutical industry, the production of capsules, particularly those made from gelatin, is a complex process that demands precision and consistency. Gelatin, a critical component in both hard and soft gelatin capsules, requires…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Calibration Failures in Temperature Sensors for Purified Water Systems

March 13, 2025 Admin

Managing Calibration Failures in Temperature Sensors for Purified Water Systems Managing Calibration Failures in Temperature Sensors for Purified Water Systems Introduction: In the pharmaceutical industry, maintaining the integrity of purified water systems is crucial for ensuring product quality and safety. Temperature sensors play a vital role in these systems by monitoring and maintaining the required…

Solid Dosage form, Tablets