Tag: Tablet Stability

Investigating Impact of Oxidative Stress on Coated Tablet Stability

April 25, 2025 Admin

Investigating Impact of Oxidative Stress on Coated Tablet Stability Investigating Impact of Oxidative Stress on Coated Tablet Stability Introduction: In the pharmaceutical industry, the stability of coated tablets is a critical factor in ensuring drug efficacy and safety over their shelf life. Coated tablets are designed to protect the active pharmaceutical ingredients (APIs) from environmental…

Solid Dosage form, Tablets

Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging

April 23, 2025 Admin

Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging Introduction: In the pharmaceutical industry, maintaining the stability and integrity of tablet formulations is crucial. Tablets are often sensitive to environmental conditions, particularly moisture, which can compromise their quality and efficacy. To mitigate this, desiccants are employed in tablet…

Solid Dosage form, Tablets

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing

April 21, 2025 Admin

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Introduction: Sugar-coated tablets are a popular dosage form in the pharmaceutical industry, valued for their aesthetic appeal and ability to mask unpleasant tastes. However, these advantages can be overshadowed by challenges encountered during stability testing, particularly disintegration…

Solid Dosage form, Tablets

Preventing Dust Accumulation in Sealing Areas for Hygroscopic Tablets

April 20, 2025 Admin

Preventing Dust Accumulation in Sealing Areas for Hygroscopic Tablets Preventing Dust Accumulation in Sealing Areas for Hygroscopic Tablets Introduction: In the pharmaceutical industry, maintaining the integrity and efficacy of hygroscopic tablets is a critical concern. These tablets are highly sensitive to moisture and can be compromised if exposed to environmental conditions that allow for dust…

Solid Dosage form, Tablets

Investigating Core Erosion in Extended Release Tablets During Stability Storage

April 13, 2025 Admin

Investigating Core Erosion in Extended Release Tablets During Stability Storage Investigating Core Erosion in Extended Release Tablets During Stability Storage Introduction: In the realm of pharmaceutical development, extended release (ER) tablets play a pivotal role in ensuring patient compliance and therapeutic efficacy. These tablets are designed to release active pharmaceutical ingredients (APIs) at a controlled…

Solid Dosage form, Tablets

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs

April 8, 2025 Admin

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, offering a palatable and aesthetically pleasing way to deliver medications. However, the process of sugar coating can present unique challenges, particularly during validation runs, a critical…

Solid Dosage form, Tablets

Managing Shrink Wrapping Challenges for Immediate Release Tablets

April 8, 2025 Admin

Managing Shrink Wrapping Challenges for Immediate Release Tablets Managing Shrink Wrapping Challenges for Immediate Release Tablets Introduction: Shrink wrapping is a crucial packaging technique used widely in the pharmaceutical industry to ensure the stability and integrity of immediate release tablets. This packaging method involves applying a plastic film around a product, which is then heated…

Solid Dosage form, Tablets

Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage

April 4, 2025 Admin

Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage Introduction: In the pharmaceutical industry, hygroscopic tablets present unique challenges due to their propensity to absorb moisture from the environment. This characteristic can adversely affect the stability, efficacy, and shelf life of the medication. Understanding and mitigating…

Solid Dosage form, Tablets

Troubleshooting Root Cause Analysis for Non-Adherence in Stability Studies

April 3, 2025 Admin

Troubleshooting Root Cause Analysis for Non-Adherence in Stability Studies Troubleshooting Root Cause Analysis for Non-Adherence in Stability Studies Introduction: Stability studies are a crucial component of the pharmaceutical development process, ensuring that drug products maintain their intended quality, safety, and efficacy throughout their shelf life. Non-adherence to stability protocols can lead to significant issues, including…

Solid Dosage form, Tablets

Preventing Over-Drying of Granules During Fluid Bed Processing

April 1, 2025 Admin

Preventing Over-Drying of Granules During Fluid Bed Processing Preventing Over-Drying of Granules During Fluid Bed Processing Introduction: Fluid bed processing is a cornerstone of pharmaceutical manufacturing, especially in the production of solid dosage forms such as tablets. The process involves suspending particles in a flowing gas stream, typically air, which facilitates the drying of granules…

Solid Dosage form, Tablets

Troubleshooting Coating Cracks During Stability Testing

March 31, 2025 Admin

Troubleshooting Coating Cracks During Stability Testing Troubleshooting Coating Cracks During Stability Testing Introduction: In the pharmaceutical industry, the stability of solid dosage forms, particularly tablets, is critical for ensuring the efficacy and safety of medication over its shelf life. Coating cracks are a prevalent issue encountered during stability testing, which can compromise the protective function…

Solid Dosage form, Tablets

Addressing Coating Layer Delamination in Sustained Release Tablets

March 29, 2025 Admin

Addressing Coating Layer Delamination in Sustained Release Tablets Addressing Coating Layer Delamination in Sustained Release Tablets Introduction: The pharmaceutical industry continually seeks to enhance drug delivery systems, with sustained release tablets being a significant innovation. These tablets are designed to release their active ingredients over an extended period, ensuring a consistent therapeutic effect and improved…

Solid Dosage form, Tablets