Tag: Tablet Stability

Addressing Non-Compliance in Process Validation for Hygroscopic Tablets

June 4, 2025 Admin

Addressing Non-Compliance in Process Validation for Hygroscopic Tablets Addressing Non-Compliance in Process Validation for Hygroscopic Tablets Introduction: In the pharmaceutical industry, the process validation of hygroscopic tablets presents unique challenges. Hygroscopic tablets are those that have a tendency to absorb moisture from their surroundings, which can lead to significant issues in their stability, efficacy, and…

Solid Dosage form, Tablets

Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing

June 2, 2025 Admin

Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing Introduction: Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the alkaline environment of the intestine. This specialized coating is crucial for the targeted delivery of certain medications, ensuring their efficacy…

Solid Dosage form, Tablets

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets

May 31, 2025 Admin

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the integrity of film-coated tablets is a critical aspect of product quality and efficacy. Film coatings on tablets serve multiple purposes, including protection from environmental factors, masking unpleasant tastes,…

Solid Dosage form, Tablets

Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets

May 30, 2025 Admin

Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the stability of sustained release tablets is paramount to maintaining efficacy and safety. These tablets are designed to release active ingredients over an extended period, offering advantages…

Solid Dosage form, Tablets

Ensuring Robustness in Layer Adhesion for Bilayer Tablet Equipment Validation

May 27, 2025 Admin

Ensuring Robustness in Layer Adhesion for Bilayer Tablet Equipment Validation Ensuring Robustness in Layer Adhesion for Bilayer Tablet Equipment Validation Introduction: In the realm of pharmaceutical manufacturing, bilayer tablets have emerged as a significant advancement, offering multiple benefits such as the ability to combine incompatible substances, controlled release profiles, and patient convenience. However, the manufacturing…

Solid Dosage form, Tablets

Root Cause Analysis of Weight Variation in Tablets During Stability Storage

May 24, 2025 Admin

Root Cause Analysis of Weight Variation in Tablets During Stability Storage Root Cause Analysis of Weight Variation in Tablets During Stability Storage Introduction: In the pharmaceutical industry, tablets remain one of the most common solid dosage forms, prized for their convenience, stability, and precise dosing. However, a critical aspect of tablet production and storage is…

Solid Dosage form, Tablets

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing

May 22, 2025 Admin

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Introduction: Enteric-coated tablets are an essential dosage form in the pharmaceutical industry, designed to withstand the acidic environment of the stomach and release active ingredients in the more neutral environment of the intestine. This protective mechanism not only enhances…

Solid Dosage form, Tablets

Managing Alignment of Desiccants in Blister Packaging for Moisture Control

May 22, 2025 Admin

Managing Alignment of Desiccants in Blister Packaging for Moisture Control Managing Alignment of Desiccants in Blister Packaging for Moisture Control Introduction: In the pharmaceutical industry, maintaining the stability and efficacy of solid dosage forms like tablets is paramount. Blister packaging is a common choice for protecting tablets from environmental factors such as moisture and light….

Solid Dosage form, Tablets

Troubleshooting Brittleness in Coated Tablets During Validation Testing

May 21, 2025 Admin

Troubleshooting Brittleness in Coated Tablets During Validation Testing Troubleshooting Brittleness in Coated Tablets During Validation Testing Introduction: In the pharmaceutical industry, tablets are a common and vital dosage form. They offer precise dosing, ease of administration, and stability. However, the process of coating tablets, which enhances their appearance, taste, and stability, can introduce challenges. One…

Solid Dosage form, Tablets

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing

May 19, 2025 Admin

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Introduction: In the pharmaceutical industry, multi-layer tablets have become a sophisticated option for delivering multiple active pharmaceutical ingredients (APIs) with distinct release profiles. These tablets offer numerous advantages, including improved patient compliance and efficient dosing schedules. However,…

Solid Dosage form, Tablets

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging

May 18, 2025 Admin

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Introduction: Sugar-coated tablets have been a mainstay in pharmaceutical formulations for decades. Their aesthetic appeal, taste masking, and ability to protect the active pharmaceutical ingredient (API) are among their numerous advantages. However, the hygroscopic nature of sugar poses a…

Solid Dosage form, Tablets

Managing Material Compatibility Issues in Packaging for Coated Tablets

May 17, 2025 Admin

Managing Material Compatibility Issues in Packaging for Coated Tablets Managing Material Compatibility Issues in Packaging for Coated Tablets Introduction: In the pharmaceutical industry, the packaging of coated tablets is a critical process that ensures the safety, efficacy, and longevity of the product. Coated tablets, designed to enhance stability, control release, and improve patient compliance, require…

Solid Dosage form, Tablets