Tag: tablet quality control

Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers

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Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of medicinal products is paramount. Enteric-coated tablets are designed to release their active ingredients in the intestine rather than the stomach, which is crucial for drugs that are sensitive to stomach…

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Solid Dosage form, Tablets

Troubleshooting Over-Drying in Coated Tablets During Finishing

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Troubleshooting Over-Drying in Coated Tablets During Finishing Troubleshooting Over-Drying in Coated Tablets During Finishing Introduction: The pharmaceutical industry is continually innovating to ensure the highest quality of products. Among the various dosage forms, coated tablets are one of the most prevalent, owing to their aesthetic appeal, ease of swallowing, and controlled release capabilities. However, the…

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Solid Dosage form, Tablets

Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets

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Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Introduction: Enteric tablets are specially designed solid dosage forms that remain intact in the acidic environment of the stomach and dissolve in the more neutral pH of the intestine. This ensures that active pharmaceutical ingredients (APIs) are released at…

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Solid Dosage form, Tablets

Ensuring Coating Uniformity in Sustained Release Tablets During Production

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Ensuring Coating Uniformity in Sustained Release Tablets During Production Ensuring Coating Uniformity in Sustained Release Tablets During Production Introduction: The production of sustained release tablets is a cornerstone of modern pharmaceutical manufacturing, offering controlled drug delivery over extended periods. Coating uniformity is crucial in these tablets to ensure consistent drug release rates, optimal therapeutic outcomes,…

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Solid Dosage form, Tablets

Preventing Crushing of Tablets During Carton Closing Operations

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Preventing Crushing of Tablets During Carton Closing Operations Preventing Crushing of Tablets During Carton Closing Operations Introduction: In the pharmaceutical industry, ensuring the integrity of tablets from production to delivery is paramount. One critical stage where tablets are susceptible to damage is during carton closing operations. The crushing of tablets not only results in financial…

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Solid Dosage form, Tablets

Common Pitfalls in Weight Uniformity Testing for Immediate Release Tablets

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Common Pitfalls in Weight Uniformity Testing for Immediate Release Tablets Common Pitfalls in Weight Uniformity Testing for Immediate Release Tablets Introduction: Weight uniformity testing is a critical quality control measure in the pharmaceutical industry, particularly for immediate release tablets. Ensuring consistency in tablet weight is essential not only for compliance with regulatory standards but also…

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Solid Dosage form, Tablets

Troubleshooting Calibration Failures in Hardness Testing Equipment

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Troubleshooting Calibration Failures in Hardness Testing Equipment Troubleshooting Calibration Failures in Hardness Testing Equipment Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid dosage forms like tablets is paramount. Hardness testing equipment plays a critical role in this process by assessing the mechanical integrity of tablets, which is crucial for both efficacy…

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Solid Dosage form, Tablets

Controlling Over-Sensitivity to Temperature in Coated Tablet Processes

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Controlling Over-Sensitivity to Temperature in Coated Tablet Processes Controlling Over-Sensitivity to Temperature in Coated Tablet Processes Introduction: In the pharmaceutical industry, coated tablets are among the most common solid dosage forms due to their advantages in masking unpleasant tastes, improving stability, and controlling drug release. However, the process of coating tablets can be highly sensitive…

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Solid Dosage form, Tablets

Troubleshooting Non-Uniform Disintegration in Coated Tablets During Testing

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Troubleshooting Non-Uniform Disintegration in Coated Tablets During Testing Troubleshooting Non-Uniform Disintegration in Coated Tablets During Testing Introduction: Coated tablets are a prevalent form of medication delivery in the pharmaceutical industry, designed to improve the stability, appearance, and release characteristics of the active pharmaceutical ingredient (API). The disintegration of these tablets is a critical quality attribute…

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Solid Dosage form, Tablets

Ensuring Adequate Desiccant Placement in Tablet Packaging for Stability

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Ensuring Adequate Desiccant Placement in Tablet Packaging for Stability Ensuring Adequate Desiccant Placement in Tablet Packaging for Stability Introduction: In the pharmaceutical industry, maintaining the stability of tablet formulations is paramount to ensure efficacy, safety, and shelf life. Tablets are susceptible to degradation from environmental factors such as humidity and temperature, making the role of…

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Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time

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Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Introduction: The pharmaceutical industry is constantly evolving, with a significant focus on developing efficient drug delivery systems. Extended release tablets are a crucial component of this landscape, designed to release active pharmaceutical ingredients (APIs) over…

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Solid Dosage form, Tablets

Addressing High Friability in Sugar-Coated Tablets

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Addressing High Friability in Sugar-Coated Tablets Addressing High Friability in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular solid dosage form due to their appealing appearance, taste masking capabilities, and ability to protect the drug core from environmental factors. However, achieving the ideal balance between coating thickness and tablet robustness is crucial to maintain product…

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Solid Dosage form, Tablets