Tag: tablet quality

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing

June 5, 2025 Admin

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Introduction: In the pharmaceutical industry, the aesthetic and functional integrity of sugar-coated tablets is paramount. The coating not only enhances the appearance but also affects consumer perception and compliance. However, during accelerated stability testing, a crucial phase…

Solid Dosage form, Tablets

Troubleshooting Over-Lubrication in Powder Blends During Compression Validation

June 1, 2025 Admin

Troubleshooting Over-Lubrication in Powder Blends During Compression Validation Troubleshooting Over-Lubrication in Powder Blends During Compression Validation Introduction: In the pharmaceutical industry, the production of tablets is a complex process that demands precision and careful attention to detail. One critical aspect of tablet manufacturing is the lubrication of powder blends, which facilitates the tablet compression process….

Solid Dosage form, Tablets

Validating Spray Gun Settings for Even Coating Distribution

June 1, 2025 Admin

Validating Spray Gun Settings for Even Coating Distribution Validating Spray Gun Settings for Even Coating Distribution Introduction: In the pharmaceutical industry, ensuring that tablets have an even coating is crucial not only for aesthetic purposes but also for the functionality of the dosage form. The coating protects the active pharmaceutical ingredient (API), controls release profiles,…

Solid Dosage form, Tablets

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets

May 31, 2025 Admin

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the integrity of film-coated tablets is a critical aspect of product quality and efficacy. Film coatings on tablets serve multiple purposes, including protection from environmental factors, masking unpleasant tastes,…

Solid Dosage form, Tablets

Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress

May 30, 2025 Admin

Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress Introduction: Film coatings are a critical component in the development of extended-release tablets, playing an essential role in the control of drug release rates, protection of the drug from environmental factors, and improving…

Solid Dosage form, Tablets

Addressing Punch Wear Issues During Tablet Press Validation

May 25, 2025 Admin

Addressing Punch Wear Issues During Tablet Press Validation Addressing Punch Wear Issues During Tablet Press Validation Introduction: In the pharmaceutical manufacturing sector, ensuring the integrity and quality of tablet products is paramount. One critical aspect of this process is the validation of tablet presses, where punch wear can significantly impact product quality and efficiency. Punches,…

Solid Dosage form, Tablets

Validating Batch Records for Regulatory Compliance in Tablet Manufacturing

May 25, 2025 Admin

Validating Batch Records for Regulatory Compliance in Tablet Manufacturing Validating Batch Records for Regulatory Compliance in Tablet Manufacturing Introduction: In the pharmaceutical industry, ensuring the integrity and accuracy of batch records is paramount, particularly in the manufacturing of tablets. Batch records serve as a critical component in the documentation of each step of the manufacturing…

Solid Dosage form, Tablets

Root Cause Analysis of Weight Variation in Tablets During Stability Storage

May 24, 2025 Admin

Root Cause Analysis of Weight Variation in Tablets During Stability Storage Root Cause Analysis of Weight Variation in Tablets During Stability Storage Introduction: In the pharmaceutical industry, tablets remain one of the most common solid dosage forms, prized for their convenience, stability, and precise dosing. However, a critical aspect of tablet production and storage is…

Solid Dosage form, Tablets

Ensuring Robustness in Disintegration Time During Validation Testing

May 24, 2025 Admin

Ensuring Robustness in Disintegration Time During Validation Testing Ensuring Robustness in Disintegration Time During Validation Testing Introduction: In the pharmaceutical industry, the disintegration time of tablets is a critical quality attribute that directly impacts drug release and bioavailability. Ensuring robustness in disintegration time during validation testing is essential to maintain consistency in therapeutic efficacy and…

Solid Dosage form, Tablets

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing

May 22, 2025 Admin

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Introduction: Enteric-coated tablets are an essential dosage form in the pharmaceutical industry, designed to withstand the acidic environment of the stomach and release active ingredients in the more neutral environment of the intestine. This protective mechanism not only enhances…

Solid Dosage form, Tablets

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing

May 19, 2025 Admin

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Introduction: In the pharmaceutical industry, multi-layer tablets have become a sophisticated option for delivering multiple active pharmaceutical ingredients (APIs) with distinct release profiles. These tablets offer numerous advantages, including improved patient compliance and efficient dosing schedules. However,…

Solid Dosage form, Tablets

Investigating Solvent Evaporation Effects on Coated Tablets During Storage

May 13, 2025 Admin

Investigating Solvent Evaporation Effects on Coated Tablets During Storage Investigating Solvent Evaporation Effects on Coated Tablets During Storage Introduction: In the pharmaceutical industry, the stability and integrity of coated tablets during storage are paramount to ensuring their efficacy and safety. Solvent evaporation is a critical factor that can affect the coating’s performance, leading to potential…

Solid Dosage form, Tablets