Tag: Tablet Production Challenges

Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets

March 22, 2025 Admin

Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets Introduction: In the pharmaceutical industry, extended release tablets play a crucial role in delivering medication over a prolonged period, enhancing patient compliance and therapeutic efficacy. However, one of the persistent challenges in their production is the non-adherence…

Solid Dosage form, Tablets

Controlling Weight Variation Across Tablet Batches

March 21, 2025 Admin

Controlling Weight Variation Across Tablet Batches Controlling Weight Variation Across Tablet Batches Introduction: In the pharmaceutical industry, ensuring the uniformity and consistency of tablets is of paramount importance. Weight variation across tablet batches can significantly impact the therapeutic efficacy and safety of a medication. Variations can lead to dosage inconsistencies, which may result in suboptimal…

Solid Dosage form, Tablets

Ensuring Consistency in Coating Thickness Measurements During QA Testing

March 20, 2025 Admin

Ensuring Consistency in Coating Thickness Measurements During QA Testing Ensuring Consistency in Coating Thickness Measurements During QA Testing Introduction: In the realm of pharmaceutical manufacturing, ensuring the consistency and quality of tablet coatings is crucial. Coating not only enhances the aesthetic appeal but also plays a significant role in controlling the release of active ingredients,…

Solid Dosage form, Tablets

Real-Time Monitoring of Tablet Thickness During Compression

March 18, 2025 Admin

Real-Time Monitoring of Tablet Thickness During Compression Real-Time Monitoring of Tablet Thickness During Compression Introduction: In the pharmaceutical industry, ensuring the consistent quality of tablets is paramount. Tablet thickness, a critical quality attribute, affects not only the tablet’s appearance but also its dissolution rate and overall efficacy. Real-time monitoring of tablet thickness during compression is…

Solid Dosage form, Tablets

Addressing Misalignment of Tablet Rows in Blister Cavities

March 18, 2025 Admin

Addressing Misalignment of Tablet Rows in Blister Cavities Addressing Misalignment of Tablet Rows in Blister Cavities Introduction: Blister packaging is a critical component in the pharmaceutical industry, ensuring product protection, tamper resistance, and patient compliance. However, one common issue faced during the packaging process is the misalignment of tablet rows in blister cavities. This misalignment…

Solid Dosage form, Tablets

Preventing Layer Cracking in Multi-Layer Tablets During Storage

March 17, 2025 Admin

Preventing Layer Cracking in Multi-Layer Tablets During Storage Preventing Layer Cracking in Multi-Layer Tablets During Storage Introduction: Multi-layer tablets are an increasingly popular pharmaceutical dosage form due to their ability to deliver multiple active ingredients with different release profiles in a single dosage unit. Despite their benefits, these tablets are susceptible to layer cracking during…

Solid Dosage form, Tablets

Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets

March 15, 2025 Admin

Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets Introduction: In the realm of pharmaceutical manufacturing, roller compaction is a critical granulation method frequently employed for the production of large-scale tablets. This process is favored for its ability to handle heat and moisture-sensitive compounds without requiring…

Solid Dosage form, Tablets

Troubleshooting Over-Drying in Coated Tablets During Finishing

March 14, 2025 Admin

Troubleshooting Over-Drying in Coated Tablets During Finishing Troubleshooting Over-Drying in Coated Tablets During Finishing Introduction: The pharmaceutical industry is continually innovating to ensure the highest quality of products. Among the various dosage forms, coated tablets are one of the most prevalent, owing to their aesthetic appeal, ease of swallowing, and controlled release capabilities. However, the…

Solid Dosage form, Tablets

Resolving Failures in Disintegration Testing for Sustained Release Tablets

March 13, 2025 Admin

Resolving Failures in Disintegration Testing for Sustained Release Tablets Resolving Failures in Disintegration Testing for Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of solid dosage forms such as tablets is paramount. Sustained release tablets, designed to release a drug at a predetermined rate, present unique challenges in quality control,…

Solid Dosage form, Tablets

Troubleshooting Residual Solvent Issues in Utility Lines for Sugar-Coated Tablets

March 10, 2025 Admin

Troubleshooting Residual Solvent Issues in Utility Lines for Sugar-Coated Tablets Troubleshooting Residual Solvent Issues in Utility Lines for Sugar-Coated Tablets Introduction: In the pharmaceutical manufacturing landscape, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and ease of swallowing. However, the manufacturing process involves various challenges, especially when it comes to managing…

Solid Dosage form, Tablets

Ensuring Robustness in Weight Variation Testing During Validation Processes

March 10, 2025 Admin

Ensuring Robustness in Weight Variation Testing During Validation Processes Ensuring Robustness in Weight Variation Testing During Validation Processes Introduction: In the pharmaceutical industry, ensuring the consistency and quality of products is paramount. Among the critical tests conducted during the validation processes of solid dosage forms, weight variation testing holds significant importance. This test ensures that…

Solid Dosage form, Tablets

Preventing Over-Drying of Hygroscopic Tablets in Fluid Bed Dryers

March 5, 2025 Admin

Preventing Over-Drying of Hygroscopic Tablets in Fluid Bed Dryers Preventing Over-Drying of Hygroscopic Tablets in Fluid Bed Dryers Introduction: In the pharmaceutical industry, maintaining the integrity and efficacy of tablet formulations is of paramount importance. Hygroscopic tablets, known for their moisture-attracting properties, present unique challenges during the drying process. Fluid bed dryers, a common tool…

Solid Dosage form, Tablets