Tag: Tablet manufacturing process​

Selecting Disintegration Aids for Sugar-Coated Tablets Tips and Tricks: Selecting Disintegration Aids for Sugar-Coated Tablets Overview: Disintegration aids are crucial in the formulation of sugar-coated tablets, as they facilitate the rapid breakdown of the tablet in the gastrointestinal tract. The sugar coating serves to protect the API, mask the taste, and provide aesthetic appeal, but…

Read More “Selecting Disintegration Aids for Sugar-Coated Tablets” »

Role of Controlled Agglomeration in Granulation Processes Expert Guide: The Role of Controlled Agglomeration in Granulation Processes Overview: Controlled agglomeration is a crucial step in the granulation process, which plays an integral role in the production of tablets and other solid dosage forms. The technique involves the controlled formation of granules by binding fine particles…

Read More “Role of Controlled Agglomeration in Granulation Processes” »

Strategies for Reducing Coating Time in Film-Coated Tablets Research & Trends: Strategies for Reducing Coating Time in Film-Coated Tablets Overview: Coating is a critical step in the tablet manufacturing process, especially for film-coated tablets, which require precise control over coating thickness, uniformity, and quality. However, coating can be a time-consuming process, and reducing coating time…

Read More “Strategies for Reducing Coating Time in Film-Coated Tablets” »

Addressing Tablet Erosion in Controlled Release Formulations How to Address Tablet Erosion in Controlled Release Formulations Overview: Tablet erosion is a common issue in controlled release (CR) tablet formulations, where the tablet erodes too quickly or inconsistently during the release process. This can lead to a burst release of the active pharmaceutical ingredient (API), causing…

Read More “Addressing Tablet Erosion in Controlled Release Formulations” »

Incorporating Nutraceuticals in Immediate Release Tablets: Challenges Case Study: Overcoming Challenges in Incorporating Nutraceuticals in Immediate Release Tablets Overview: Incorporating nutraceuticals into pharmaceutical formulations, particularly in immediate release (IR) tablets, presents several challenges. Nutraceuticals, which include dietary supplements, vitamins, minerals, and herbal extracts, often have different physicochemical properties than conventional APIs. These differences can make…

Read More “Incorporating Nutraceuticals in Immediate Release Tablets: Challenges” »

Excipient-Drug Interaction Studies in Extended Release Tablets A Step-by-Step Guide to Excipient-Drug Interaction Studies in Extended Release Tablets Overview: Excipient-drug interactions are a crucial consideration in the development of extended release (ER) tablets. The selection of excipients, including binders, fillers, disintegrants, and polymers, can significantly affect the release profile of the active pharmaceutical ingredient (API)….

Read More “Excipient-Drug Interaction Studies in Extended Release Tablets” »

Role of Pre-Formulation Studies in Tablet Development The Importance of Pre-Formulation Studies in Tablet Development Overview: Pre-formulation studies are a critical phase in the development of pharmaceutical tablets. These studies involve assessing the physical and chemical properties of the active pharmaceutical ingredient (API) and excipients, which serve as the foundation for successful tablet formulation. The…

Read More “Role of Pre-Formulation Studies in Tablet Development” »

Strategies to Minimize Friability in Tablets During Development Effective Strategies to Minimize Friability in Tablets During Development Overview: Friability is a critical factor in tablet formulation, referring to the tendency of tablets to break or crumble under stress during handling, transport, and storage. A high friability rate indicates poor tablet strength and can lead to…

Read More “Strategies to Minimize Friability in Tablets During Development” »