Tag: tablet layer separation

Troubleshooting Uneven Compression Force in Multi-Layer Tablets

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Troubleshooting Uneven Compression Force in Multi-Layer Tablets Troubleshooting Uneven Compression Force in Multi-Layer Tablets Introduction: In the pharmaceutical industry, multi-layer tablets represent a crucial innovation, offering benefits such as multiple drug release profiles and combinations in a single dose. However, the manufacturing of these tablets comes with its own set of challenges. One significant issue…

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Solid Dosage form, Tablets

Troubleshooting Layer Cracks in Bilayer Tablets During Validation

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Troubleshooting Layer Cracks in Bilayer Tablets During Validation Troubleshooting Layer Cracks in Bilayer Tablets During Validation Introduction: Bilayer tablets have gained significant traction in the pharmaceutical industry due to their ability to deliver multiple drugs with distinct release profiles in a single dosage form. However, during the manufacturing process, these tablets can present unique challenges,…

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Solid Dosage form, Tablets

Preventing Core Breakage in Multi-Layer Tablets During Compression

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Preventing Core Breakage in Multi-Layer Tablets During Compression Preventing Core Breakage in Multi-Layer Tablets During Compression Introduction: In the pharmaceutical industry, the development of multi-layer tablets offers a strategic approach to deliver multiple active pharmaceutical ingredients (APIs) or to control the release profiles of medications. However, the manufacturing of these complex dosage forms presents unique…

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Solid Dosage form, Tablets

Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing

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Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Introduction: Multi-layer tablets have emerged as a significant innovation in the pharmaceutical industry, offering the advantage of delivering multiple drugs or the same drug at different release rates within a single dosage form. However, one of the critical challenges…

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Solid Dosage form, Tablets