Tag: Tablet formulation

Addressing Deviations in Stability Studies for Bilayer Tablets

April 27, 2025 Admin

Addressing Deviations in Stability Studies for Bilayer Tablets Addressing Deviations in Stability Studies for Bilayer Tablets Introduction: Bilayer tablets have emerged as a versatile drug delivery system, offering the advantage of combining two different drugs or formulations with varied release profiles in a single dosage form. This innovation not only improves patient compliance but also…

Solid Dosage form, Tablets

Investigating Impact of Oxidative Stress on Coated Tablet Stability

April 25, 2025 Admin

Investigating Impact of Oxidative Stress on Coated Tablet Stability Investigating Impact of Oxidative Stress on Coated Tablet Stability Introduction: In the pharmaceutical industry, the stability of coated tablets is a critical factor in ensuring drug efficacy and safety over their shelf life. Coated tablets are designed to protect the active pharmaceutical ingredients (APIs) from environmental…

Solid Dosage form, Tablets

Resolving Tablet Displacement in Blister Cavities During Packaging

April 25, 2025 Admin

Resolving Tablet Displacement in Blister Cavities During Packaging Resolving Tablet Displacement in Blister Cavities During Packaging Introduction: In the pharmaceutical industry, the packaging of solid dosage forms like tablets is a critical process that ensures product integrity, stability, and patient safety. Blister packaging is one of the most common methods used to protect tablets from…

Solid Dosage form, Tablets

Addressing Over-Drying Issues in Granulation During Validation Runs

April 24, 2025 Admin

Addressing Over-Drying Issues in Granulation During Validation Runs Addressing Over-Drying Issues in Granulation During Validation Runs Introduction: In the pharmaceutical industry, granulation is a critical step in the production of solid dosage forms such as tablets. It involves the agglomeration of powder particles to form granules, which enhance the flowability and compressibility of the powder,…

Solid Dosage form, Tablets

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing

April 21, 2025 Admin

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Introduction: Sugar-coated tablets are a popular dosage form in the pharmaceutical industry, valued for their aesthetic appeal and ability to mask unpleasant tastes. However, these advantages can be overshadowed by challenges encountered during stability testing, particularly disintegration…

Solid Dosage form, Tablets

Ensuring Robustness in Compression Force Settings During Validation Processes

April 18, 2025 Admin

Ensuring Robustness in Compression Force Settings During Validation Processes Ensuring Robustness in Compression Force Settings During Validation Processes Introduction: In the pharmaceutical industry, ensuring the robustness of compression force settings during the validation of tablet production is crucial. Compression force is a critical parameter that affects the mechanical strength, dissolution, and overall quality of the…

Solid Dosage form, Tablets

Ensuring Consistent Strip Sealing Quality for Multi-API Tablets

April 15, 2025 Admin

Ensuring Consistent Strip Sealing Quality for Multi-API Tablets Ensuring Consistent Strip Sealing Quality for Multi-API Tablets Introduction: In the pharmaceutical industry, ensuring the integrity and quality of tablet packaging is paramount, especially for multi-active pharmaceutical ingredient (multi-API) tablets. These complex formulations require precise handling and packaging to maintain efficacy and safety. Strip sealing is a…

Solid Dosage form, Tablets

Addressing Color Changes in Film-Coated Tablets During Stability Studies

April 14, 2025 Admin

Addressing Color Changes in Film-Coated Tablets During Stability Studies Addressing Color Changes in Film-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, maintaining the integrity and appearance of film-coated tablets throughout their shelf life is crucial. Stability studies play a significant role in ensuring that these products meet quality standards over time. One common…

Solid Dosage form, Tablets

Ensuring Consistency in Binder Addition During Wet Granulation Validation

April 14, 2025 Admin

Ensuring Consistency in Binder Addition During Wet Granulation Validation Ensuring Consistency in Binder Addition During Wet Granulation Validation Introduction: In the world of pharmaceutical manufacturing, wet granulation remains a cornerstone technique for producing tablets. The process involves the addition of a binder solution to the powder mix to form granules, which are then compressed to…

Solid Dosage form, Tablets

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time

April 13, 2025 Admin

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, maintaining the potency of the Active Pharmaceutical Ingredient (API)…

Solid Dosage form, Tablets

Ensuring Consistency in Hardness Testing Across Tablet Batches

April 10, 2025 Admin

Ensuring Consistency in Hardness Testing Across Tablet Batches Ensuring Consistency in Hardness Testing Across Tablet Batches Introduction: In the pharmaceutical industry, ensuring the consistency and quality of tablet batches is paramount. Among the various quality attributes, hardness is a critical parameter that significantly impacts the tablet’s integrity, disintegration, and dissolution profiles. Inconsistencies in hardness can…

Solid Dosage form, Tablets

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs

April 8, 2025 Admin

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, offering a palatable and aesthetically pleasing way to deliver medications. However, the process of sugar coating can present unique challenges, particularly during validation runs, a critical…

Solid Dosage form, Tablets