Tag: Tablet formulation

Ensuring Even Coating Thickness in Irregularly Shaped Tablets

March 16, 2025 Admin

Ensuring Even Coating Thickness in Irregularly Shaped Tablets Ensuring Even Coating Thickness in Irregularly Shaped Tablets Introduction: In the pharmaceutical industry, tablets are a widely used solid dosage form due to their convenience, stability, and ease of mass production. Coating these tablets serves multiple purposes, including masking unpleasant tastes, enhancing swallowability, and protecting the active…

Solid Dosage form, Tablets

How to Prevent Tablet Core Erosion in Multilayer Tablet Manufacturing

March 16, 2025 Admin

How to Prevent Tablet Core Erosion in Multilayer Tablet Manufacturing Step-by-Step Guide to Preventing Tablet Core Erosion in Multilayer Tablet Manufacturing What is Tablet Core Erosion in Multilayer Tablets? Tablet core erosion occurs when the inner layer or core of a multilayer tablet degrades or disintegrates prematurely. This can compromise the tablet’s structural integrity, alter…

Tablets

Troubleshooting Tablet Ejection Problems During Compression

March 16, 2025 Admin

Troubleshooting Tablet Ejection Problems During Compression FAQs on Troubleshooting Tablet Ejection Problems During Compression What Are Tablet Ejection Problems? Tablet ejection problems occur during the final stage of compression when the tablet is pushed out of the die cavity by the lower punch. These issues can include sticking, chipping, cracking, or excessive ejection force, leading…

Tablets

Troubleshooting Layer Cracks in Bilayer Tablets During Validation

March 15, 2025 Admin

Troubleshooting Layer Cracks in Bilayer Tablets During Validation Troubleshooting Layer Cracks in Bilayer Tablets During Validation Introduction: Bilayer tablets have gained significant traction in the pharmaceutical industry due to their ability to deliver multiple drugs with distinct release profiles in a single dosage form. However, during the manufacturing process, these tablets can present unique challenges,…

Solid Dosage form, Tablets

Managing Excessive Binder Use in Wet Granulation Processes

March 15, 2025 Admin

Managing Excessive Binder Use in Wet Granulation Processes Managing Excessive Binder Use in Wet Granulation Processes Introduction: In the pharmaceutical industry, wet granulation is a crucial process used to improve the flowability and compressibility of powder blends, ultimately ensuring the production of high-quality tablets. Binders play an essential role in wet granulation, providing the necessary…

Solid Dosage form, Tablets

How to Reduce Cycle Time in High-Speed Tablet Press Machines

March 15, 2025 Admin

How to Reduce Cycle Time in High-Speed Tablet Press Machines Effective Strategies to Reduce Cycle Time in High-Speed Tablet Press Machines What is Cycle Time in Tablet Press Machines? Cycle time refers to the time it takes for a tablet press machine to complete a single cycle, from filling the die to ejecting the finished…

Tablets

Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets

March 15, 2025 Admin

Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets Addressing Fines Segregation in Roller Compaction for Large-Scale Tablets Introduction: In the realm of pharmaceutical manufacturing, roller compaction is a critical granulation method frequently employed for the production of large-scale tablets. This process is favored for its ability to handle heat and moisture-sensitive compounds without requiring…

Solid Dosage form, Tablets

Managing Hardness Failures in Bilayer Tablets During Testing

March 15, 2025 Admin

Managing Hardness Failures in Bilayer Tablets During Testing Managing Hardness Failures in Bilayer Tablets During Testing Introduction: In the pharmaceutical industry, bilayer tablets have emerged as a sophisticated solution for delivering multiple drugs or varied release profiles within a single dosage form. This innovation not only enhances patient compliance but also optimizes therapeutic efficacy by…

Solid Dosage form, Tablets

Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles

March 15, 2025 Admin

Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their aesthetic appeal and ability to mask the taste of active pharmaceutical ingredients (APIs). However, the stability of these tablets can be significantly challenged…

Solid Dosage form, Tablets

Enhancing Sustainability in Tablet Manufacturing Processes

March 15, 2025 Admin

Enhancing Sustainability in Tablet Manufacturing Processes FAQs on Enhancing Sustainability in Tablet Manufacturing Processes Why is Sustainability Important in Tablet Manufacturing? Sustainability in tablet manufacturing aims to reduce environmental impact, conserve resources, and ensure compliance with global environmental regulations. By adopting eco-friendly practices, manufacturers can reduce energy consumption, minimize waste, and create sustainable supply chains…

Tablets

Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers

March 15, 2025 Admin

Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of medicinal products is paramount. Enteric-coated tablets are designed to release their active ingredients in the intestine rather than the stomach, which is crucial for drugs that are sensitive to stomach…

Solid Dosage form, Tablets

Addressing Challenges in Friability Testing for Sugar-Coated Tablets

March 15, 2025 Admin

Addressing Challenges in Friability Testing for Sugar-Coated Tablets Addressing Challenges in Friability Testing for Sugar-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the quality and durability of solid dosage forms like tablets is paramount. Among the various quality control tests, friability testing is crucial as it assesses a tablet’s ability to withstand mechanical stresses during…

Solid Dosage form, Tablets