Tag: Tablet formulation

Preventing Overheating of Punches in High-Pressure Tablet Compression

March 18, 2025 Admin

Preventing Overheating of Punches in High-Pressure Tablet Compression FAQs on Preventing Overheating of Punches in High-Pressure Tablet Compression Why is Overheating of Punches a Concern in Tablet Compression? Overheating of punches during high-pressure tablet compression can lead to increased wear and tear, reduced punch lifespan, sticking issues, and compromised tablet quality. Prolonged exposure to high…

Tablets

Managing Fines Generation During Compression of Immediate Release Tablets

March 17, 2025 Admin

Managing Fines Generation During Compression of Immediate Release Tablets Managing Fines Generation During Compression of Immediate Release Tablets Introduction: In the pharmaceutical industry, the production of immediate-release tablets is a crucial process that requires meticulous attention to detail. One of the significant challenges faced during the tablet manufacturing process is the generation of fines. Fines…

Solid Dosage form, Tablets

Identifying Causes of Tablet Swelling During Disintegration Testing

March 17, 2025 Admin

Identifying Causes of Tablet Swelling During Disintegration Testing Identifying Causes of Tablet Swelling During Disintegration Testing Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of solid dosage forms, such as tablets, is paramount. A critical aspect of this quality control is disintegration testing, a process that evaluates how quickly a tablet breaks down…

Solid Dosage form, Tablets

Preventing Layer Cracking in Multi-Layer Tablets During Storage

March 17, 2025 Admin

Preventing Layer Cracking in Multi-Layer Tablets During Storage Preventing Layer Cracking in Multi-Layer Tablets During Storage Introduction: Multi-layer tablets are an increasingly popular pharmaceutical dosage form due to their ability to deliver multiple active ingredients with different release profiles in a single dosage unit. Despite their benefits, these tablets are susceptible to layer cracking during…

Solid Dosage form, Tablets

How to Ensure Machine Calibration for Tablet Weight Consistency

March 17, 2025 Admin

How to Ensure Machine Calibration for Tablet Weight Consistency Step-by-Step Guide to Ensuring Machine Calibration for Tablet Weight Consistency Why is Machine Calibration Essential for Tablet Weight Consistency? Machine calibration ensures that tablet press machines produce tablets with consistent weight, which is critical for maintaining dosage accuracy, regulatory compliance, and product quality. Improper calibration can…

Tablets

Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets

March 17, 2025 Admin

Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, achieving a uniform color distribution on these tablets can be challenging. Uneven color distribution not only…

Solid Dosage form, Tablets

Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets

March 17, 2025 Admin

Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry, offering advantages such as ease of swallowing, masking of unpleasant tastes, and aesthetic appeal. However, achieving a consistent and uniform color distribution during the sugar-coating process can be…

Solid Dosage form, Tablets

Addressing Challenges in Friability Testing for High-Speed Compression Tablets

March 17, 2025 Admin

Addressing Challenges in Friability Testing for High-Speed Compression Tablets Addressing Challenges in Friability Testing for High-Speed Compression Tablets Introduction: In the pharmaceutical industry, tablets remain one of the most common dosage forms due to their convenience, stability, and ease of administration. However, ensuring the integrity and quality of tablets, especially those produced at high speed,…

Solid Dosage form, Tablets

Managing Tablet Surface Defects in Large-Scale Manufacturing

March 17, 2025 Admin

Managing Tablet Surface Defects in Large-Scale Manufacturing Comprehensive Guide to Managing Tablet Surface Defects in Large-Scale Manufacturing What Are Tablet Surface Defects? Tablet surface defects are visible imperfections on the surface of tablets, such as picking, sticking, capping, chipping, or discoloration. These defects can affect product quality, patient acceptance, and regulatory compliance, leading to batch…

Tablets

Troubleshooting Uneven Compression Force in Multi-Layer Tablets

March 16, 2025 Admin

Troubleshooting Uneven Compression Force in Multi-Layer Tablets Troubleshooting Uneven Compression Force in Multi-Layer Tablets Introduction: In the pharmaceutical industry, multi-layer tablets represent a crucial innovation, offering benefits such as multiple drug release profiles and combinations in a single dose. However, the manufacturing of these tablets comes with its own set of challenges. One significant issue…

Solid Dosage form, Tablets

Ensuring Consistency in Dissolution Testing for Multi-API Tablets

March 16, 2025 Admin

Ensuring Consistency in Dissolution Testing for Multi-API Tablets Ensuring Consistency in Dissolution Testing for Multi-API Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, particularly for tablets containing multiple active pharmaceutical ingredients (APIs). Ensuring consistency in dissolution testing is vital as it impacts the tablet’s efficacy, safety, and regulatory compliance….

Solid Dosage form, Tablets

Preventing Adhesion Failures in Multi-Layer Tablet Compression

March 16, 2025 Admin

Preventing Adhesion Failures in Multi-Layer Tablet Compression Preventing Adhesion Failures in Multi-Layer Tablet Compression Introduction: In the pharmaceutical industry, the production of multi-layer tablets has become increasingly popular due to their ability to deliver multiple drugs or release profiles simultaneously. However, one of the significant challenges faced during the manufacturing process is adhesion failure between…

Solid Dosage form, Tablets