Tag: Tablet Formulation Optimization]

Troubleshooting Brittleness in High-Dose Tablets During Compression Validation

May 17, 2025 Admin

Troubleshooting Brittleness in High-Dose Tablets During Compression Validation Troubleshooting Brittleness in High-Dose Tablets During Compression Validation Introduction: In the pharmaceutical industry, tablet formulation and manufacturing represent critical processes that significantly impact the quality, efficacy, and safety of the final product. High-dose tablets are particularly challenging to develop due to the increased risks of brittleness, which…

Solid Dosage form, Tablets

Managing Over-Compression in Tablets Prone to Brittleness

March 30, 2025 Admin

Managing Over-Compression in Tablets Prone to Brittleness Managing Over-Compression in Tablets Prone to Brittleness Introduction: In the pharmaceutical industry, tablet formulation and manufacturing are critical processes that ensure medication efficacy and patient safety. Among the numerous challenges faced in tablet production, managing over-compression in tablets prone to brittleness stands out. Over-compression can lead to brittle…

Solid Dosage form, Tablets

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time

March 5, 2025 Admin

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Introduction: The pharmaceutical industry is constantly evolving, with a significant focus on developing efficient drug delivery systems. Extended release tablets are a crucial component of this landscape, designed to release active pharmaceutical ingredients (APIs) over…

Solid Dosage form, Tablets

Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing

March 4, 2025 Admin

Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Introduction: Multi-layer tablets have emerged as a significant innovation in the pharmaceutical industry, offering the advantage of delivering multiple drugs or the same drug at different release rates within a single dosage form. However, one of the critical challenges…

Solid Dosage form, Tablets