Tag: tablet dissolution

Ensuring Compliance with Regulatory Guidelines for Extended Release Tablets

March 14, 2025 Admin

Ensuring Compliance with Regulatory Guidelines for Extended Release Tablets Ensuring Compliance with Regulatory Guidelines for Extended Release Tablets Introduction: Extended release tablets are a crucial innovation in pharmaceutical dosage forms, designed to release active pharmaceutical ingredients (APIs) over an extended period. This delivery system improves patient adherence, optimizes therapeutic outcomes, and reduces dosing frequency. However,…

Solid Dosage form, Tablets

Troubleshooting Variability in Dissolution Profiles During Stability Studies

March 14, 2025 Admin

Troubleshooting Variability in Dissolution Profiles During Stability Studies Troubleshooting Variability in Dissolution Profiles During Stability Studies Introduction: Dissolution testing is a critical aspect of pharmaceutical development, acting as a quality control measure to ensure that tablets release their active ingredients at the intended rate and extent. During stability studies, the variability in dissolution profiles can…

Solid Dosage form, Tablets

Resolving Failures in Disintegration Testing for High-Dose Tablets

March 10, 2025 Admin

Resolving Failures in Disintegration Testing for High-Dose Tablets Resolving Failures in Disintegration Testing for High-Dose Tablets Introduction: In the pharmaceutical industry, the production of high-dose tablets is a critical process that requires rigorous quality control measures to ensure efficacy and safety. Disintegration testing serves as a cornerstone in evaluating the performance of these tablets, as…

Solid Dosage form, Tablets

Ensuring Robustness in Disintegration Tests for High-Dose Tablets

March 5, 2025 Admin

Ensuring Robustness in Disintegration Tests for High-Dose Tablets Ensuring Robustness in Disintegration Tests for High-Dose Tablets Introduction: In the pharmaceutical industry, high-dose tablets serve as a critical vehicle for delivering therapeutic agents effectively. Disintegration tests are essential for ensuring that these tablets dissolve appropriately, releasing their active ingredients for absorption. For high-dose tablets, achieving reliable…

Solid Dosage form, Tablets

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time

March 5, 2025 Admin

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Introduction: The pharmaceutical industry is constantly evolving, with a significant focus on developing efficient drug delivery systems. Extended release tablets are a crucial component of this landscape, designed to release active pharmaceutical ingredients (APIs) over…

Solid Dosage form, Tablets

Ensuring Robustness in Thickness Testing for Extended Release Tablets

March 4, 2025 Admin

Ensuring Robustness in Thickness Testing for Extended Release Tablets Ensuring Robustness in Thickness Testing for Extended Release Tablets Introduction: In the pharmaceutical industry, maintaining the robustness and consistency of extended release tablets is paramount for both efficacy and safety. Thickness testing of these tablets plays a crucial role in ensuring their quality and performance. Variability…

Solid Dosage form, Tablets

Validating Residual Solvent Control Measures in Coated Tablets

March 2, 2025 Admin

Validating Residual Solvent Control Measures in Coated Tablets Validating Residual Solvent Control Measures in Coated Tablets Introduction: Residual solvents are volatile chemicals used or produced in the manufacture of pharmaceutical substances, excipients, or in the preparation of drug products. Their presence in pharmaceuticals is a critical quality and safety concern, especially in coated tablets where…

Solid Dosage form, Tablets