Tag: Tablet defects

Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets

March 22, 2025 Admin

Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets Introduction: In the pharmaceutical industry, film-coated tablets represent a significant portion of solid dosage forms due to their enhanced stability, ease of swallowing, and aesthetic attributes. The coating process is critical, as it affects the tablet’s performance and patient…

Solid Dosage form, Tablets

Troubleshooting Brittleness Failures in Immediate Release Tablets

March 21, 2025 Admin

Troubleshooting Brittleness Failures in Immediate Release Tablets Troubleshooting Brittleness Failures in Immediate Release Tablets Introduction: Immediate release tablets represent a significant portion of the pharmaceutical market due to their convenience and effectiveness in delivering medication rapidly. However, brittleness failures in these tablets can pose substantial challenges, affecting their integrity and therapeutic efficacy. Brittleness, often resulting…

Solid Dosage form, Tablets

Identifying Root Causes of Poor Disintegration in Film-Coated Tablets

March 21, 2025 Admin

Identifying Root Causes of Poor Disintegration in Film-Coated Tablets Identifying Root Causes of Poor Disintegration in Film-Coated Tablets Introduction: Film-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their enhanced stability, ease of ingestion, and ability to mask unpleasant tastes. However, one critical quality attribute for these tablets is their…

Solid Dosage form, Tablets

Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage

March 20, 2025 Admin

Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage Introduction: Sugar-coated tablets remain a popular choice in the pharmaceutical industry due to their aesthetic appeal and ability to mask unpleasant tastes. However, maintaining their quality over time, especially during stability storage, presents challenges such as surface…

Solid Dosage form, Tablets

Preventing Cracking in Coated Tablets Due to Temperature Fluctuations

March 20, 2025 Admin

Preventing Cracking in Coated Tablets Due to Temperature Fluctuations Preventing Cracking in Coated Tablets Due to Temperature Fluctuations Introduction: In the pharmaceutical industry, the integrity of coated tablets is crucial for ensuring their efficacy and stability. Coated tablets are designed to provide a protective layer that can enhance the product’s shelf life, mask unpleasant tastes,…

Solid Dosage form, Tablets

Addressing Core Crumbling in Multi-Layer Tablet Compression

March 20, 2025 Admin

Addressing Core Crumbling in Multi-Layer Tablet Compression Addressing Core Crumbling in Multi-Layer Tablet Compression Introduction: The pharmaceutical industry constantly strives to improve the quality and efficacy of solid dosage forms, particularly tablets. Multi-layer tablets have gained popularity due to their ability to deliver more than one active ingredient with different release profiles. However, the manufacturing…

Solid Dosage form, Tablets

Preventing Brittleness in Coated Tablets During High-Speed Compression

March 20, 2025 Admin

Preventing Brittleness in Coated Tablets During High-Speed Compression Preventing Brittleness in Coated Tablets During High-Speed Compression Introduction: In the pharmaceutical industry, the production of coated tablets is a complex process that requires meticulous attention to detail. Coated tablets are favored for their ability to mask unpleasant tastes, protect the drug from the stomach environment, and…

Solid Dosage form, Tablets

Common Issues in Batch Sampling for Quality Testing of Tablets

March 19, 2025 Admin

Common Issues in Batch Sampling for Quality Testing of Tablets Common Issues in Batch Sampling for Quality Testing of Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of tablet batches is paramount. Batch sampling is a critical process that involves selecting a representative sample from a production batch to assess the quality…

Solid Dosage form, Tablets

Troubleshooting Cracking in Enteric-Coated Tablets During Drying

March 19, 2025 Admin

Troubleshooting Cracking in Enteric-Coated Tablets During Drying Troubleshooting Cracking in Enteric-Coated Tablets During Drying Introduction: Enteric-coated tablets are a vital component of modern pharmaceuticals, designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine. This targeted delivery is crucial for the efficacy and safety of certain…

Solid Dosage form, Tablets

Real-Time Detection of Defects in Coated Tablet Layers

March 19, 2025 Admin

Real-Time Detection of Defects in Coated Tablet Layers Real-Time Detection of Defects in Coated Tablet Layers Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of tablets is of paramount importance. Coated tablets are widely used not only for aesthetic purposes but also to enhance stability, control release profiles, and mask unpleasant tastes. However,…

Solid Dosage form, Tablets

Managing Over-Compression in Tablets with High-Dose APIs

March 18, 2025 Admin

Managing Over-Compression in Tablets with High-Dose APIs Managing Over-Compression in Tablets with High-Dose APIs Introduction: The pharmaceutical industry is increasingly challenged with the development and manufacturing of tablets that contain high-dose Active Pharmaceutical Ingredients (APIs). While these tablets are crucial for ensuring therapeutic efficacy, they come with a unique set of challenges, particularly in terms…

Solid Dosage form, Tablets

Preventing Powder Loss During Tablet Compression

March 18, 2025 Admin

Preventing Powder Loss During Tablet Compression Preventing Powder Loss During Tablet Compression Introduction: Tablet compression is a critical process in pharmaceutical manufacturing, responsible for converting powder into solid dosage forms like tablets. Ensuring efficiency during this process is vital for maintaining product quality, consistency, and cost-effectiveness. Powder loss during tablet compression can lead to significant…

Solid Dosage form, Tablets