Tag: tablet consistency

Validating Adequacy of Binder Concentration in Wet Granulation Processes

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Validating Adequacy of Binder Concentration in Wet Granulation Processes Validating Adequacy of Binder Concentration in Wet Granulation Processes Introduction: In the realm of pharmaceutical manufacturing, the wet granulation process is a cornerstone for producing high-quality tablets. Ensuring the adequacy of binder concentration is critical in this process, as it directly influences the tablet’s integrity, dissolution…

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Solid Dosage form, Tablets

Addressing Non-Homogeneity in Powder Blends for Multi-API Tablets

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Addressing Non-Homogeneity in Powder Blends for Multi-API Tablets Addressing Non-Homogeneity in Powder Blends for Multi-API Tablets Introduction: In the pharmaceutical industry, the production of multi-API (Active Pharmaceutical Ingredient) tablets requires precise formulation and meticulous blending to ensure each tablet meets stringent quality standards. Achieving homogeneity in powder blends is crucial for ensuring that every tablet…

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Solid Dosage form, Tablets

Managing Failures in Weight Variation Testing for Sustained Release Tablets

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Managing Failures in Weight Variation Testing for Sustained Release Tablets Managing Failures in Weight Variation Testing for Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the consistent quality of sustained release tablets is crucial, as they are designed to release medication over an extended period. Weight variation testing is a critical quality control measure…

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Solid Dosage form, Tablets

Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions

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Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Introduction: In the pharmaceutical industry, ensuring the consistency and quality of tablets is paramount. One of the critical quality attributes is tablet weight, which can be significantly affected by environmental conditions, particularly humidity. Weight variations…

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Solid Dosage form, Tablets

Managing Non-Uniform API Distribution in Content Uniformity Tests

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Managing Non-Uniform API Distribution in Content Uniformity Tests Managing Non-Uniform API Distribution in Content Uniformity Tests Introduction: The uniform distribution of the Active Pharmaceutical Ingredient (API) in solid dosage forms, such as tablets, is a critical quality attribute in pharmaceutical manufacturing. The reliability of therapeutic outcomes and patient safety hinges on the consistent delivery of…

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Solid Dosage form, Tablets