Tag: Tablet coating techniques​

Strategies for Reducing Coating Time in Film-Coated Tablets Research & Trends: Strategies for Reducing Coating Time in Film-Coated Tablets Overview: Coating is a critical step in the tablet manufacturing process, especially for film-coated tablets, which require precise control over coating thickness, uniformity, and quality. However, coating can be a time-consuming process, and reducing coating time…

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Addressing Tablet Erosion in Controlled Release Formulations How to Address Tablet Erosion in Controlled Release Formulations Overview: Tablet erosion is a common issue in controlled release (CR) tablet formulations, where the tablet erodes too quickly or inconsistently during the release process. This can lead to a burst release of the active pharmaceutical ingredient (API), causing…

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Incorporating Nutraceuticals in Immediate Release Tablets: Challenges Case Study: Overcoming Challenges in Incorporating Nutraceuticals in Immediate Release Tablets Overview: Incorporating nutraceuticals into pharmaceutical formulations, particularly in immediate release (IR) tablets, presents several challenges. Nutraceuticals, which include dietary supplements, vitamins, minerals, and herbal extracts, often have different physicochemical properties than conventional APIs. These differences can make…

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Excipient-Drug Interaction Studies in Extended Release Tablets A Step-by-Step Guide to Excipient-Drug Interaction Studies in Extended Release Tablets Overview: Excipient-drug interactions are a crucial consideration in the development of extended release (ER) tablets. The selection of excipients, including binders, fillers, disintegrants, and polymers, can significantly affect the release profile of the active pharmaceutical ingredient (API)….

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Role of Pre-Formulation Studies in Tablet Development The Importance of Pre-Formulation Studies in Tablet Development Overview: Pre-formulation studies are a critical phase in the development of pharmaceutical tablets. These studies involve assessing the physical and chemical properties of the active pharmaceutical ingredient (API) and excipients, which serve as the foundation for successful tablet formulation. The…

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Strategies to Minimize Friability in Tablets During Development Effective Strategies to Minimize Friability in Tablets During Development Overview: Friability is a critical factor in tablet formulation, referring to the tendency of tablets to break or crumble under stress during handling, transport, and storage. A high friability rate indicates poor tablet strength and can lead to…

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Formulation Challenges in Orally Disintegrating Tablets Overcoming Formulation Challenges in Orally Disintegrating Tablets Overview: Orally disintegrating tablets (ODTs) are designed to dissolve or disintegrate rapidly in the mouth without the need for water, offering an easy-to-administer option for patients, especially those with swallowing difficulties. ODTs are commonly used for pediatric, geriatric, and certain psychiatric medications,…

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Achieving Consistent Release Profiles in Sustained Release Tablets Strategies for Achieving Consistent Release Profiles in Sustained Release Tablets Overview: Sustained release (SR) tablets are designed to release the active pharmaceutical ingredient (API) over an extended period, allowing for more consistent therapeutic effects with fewer doses. Achieving consistent release profiles in SR tablets is critical to…

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Issues with Overuse of Coating Polymers in Sugar-Coated Tablets Addressing the Challenges of Overuse of Coating Polymers in Sugar-Coated Tablets Overview: Sugar coating is a popular tablet formulation technique that provides a protective layer around the active pharmaceutical ingredient (API). This coating improves tablet appearance, masks unpleasant taste, and protects the API from environmental factors….

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