Tag: storage conditions

Challenges in determining the impact of low-temperature storage on capsule shells.

April 7, 2025 Admin

Challenges in determining the impact of low-temperature storage on capsule shells. Challenges in determining the impact of low-temperature storage on capsule shells. Introduction: The pharmaceutical industry significantly relies on capsules as a solid oral dosage form due to their versatility and effectiveness in delivering active pharmaceutical ingredients (APIs). Capsules, whether hard or soft gelatin, provide…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring consistent capsule sealing over long-term storage.

April 5, 2025 Admin

Difficulty in ensuring consistent capsule sealing over long-term storage. Difficulty in Ensuring Consistent Capsule Sealing Over Long-Term Storage Introduction: Capsules, whether hard or soft gelatin, are a popular solid oral dosage form used in the pharmaceutical industry for their ease of use and ability to encapsulate a range of substances. However, ensuring consistent capsule sealing…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage

April 4, 2025 Admin

Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage Resolving Moisture Absorption Issues in Hygroscopic Tablets During Storage Introduction: In the pharmaceutical industry, hygroscopic tablets present unique challenges due to their propensity to absorb moisture from the environment. This characteristic can adversely affect the stability, efficacy, and shelf life of the medication. Understanding and mitigating…

Solid Dosage form, Tablets

Poor reproducibility in gelatin cross-linking data under various storage conditions.

April 4, 2025 Admin

Poor reproducibility in gelatin cross-linking data under various storage conditions. Poor Reproducibility in Gelatin Cross-Linking Data Under Various Storage Conditions Introduction: In the pharmaceutical industry, the stability and integrity of solid oral dosage forms, particularly capsules, are paramount. Gelatin, a common excipient used in hard and soft capsules, undergoes a process known as cross-linking, which…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in gelatin elasticity data under various storage conditions.

March 31, 2025 Admin

Poor reproducibility in gelatin elasticity data under various storage conditions. Poor reproducibility in gelatin elasticity data under various storage conditions. Introduction: Gelatin capsules, both hard and soft gelatin, are pivotal in the pharmaceutical industry as they offer a stable and effective medium for drug delivery. However, the elasticity of gelatin, a critical factor in capsule…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Failures in Stability Testing for Film-Coated Tablets

March 30, 2025 Admin

Troubleshooting Failures in Stability Testing for Film-Coated Tablets Troubleshooting Failures in Stability Testing for Film-Coated Tablets Introduction: Stability testing is a critical component in the lifecycle of any pharmaceutical product, especially for film-coated tablets. These tests ensure that the product maintains its intended efficacy, safety, and quality throughout its shelf life. Stability testing evaluates how…

Solid Dosage form, Tablets

Inadequate validation of capsule performance under variable storage conditions.

March 22, 2025 Admin

Inadequate validation of capsule performance under variable storage conditions. Inadequate validation of capsule performance under variable storage conditions Introduction: In the pharmaceutical industry, ensuring the stability and performance of dosage forms, such as capsules, under varying storage conditions is crucial. Capsules, whether hard or soft gelatin, are popular for their ease of administration and ability…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor adhesion of labels to packaging materials.

March 17, 2025 Admin

Poor adhesion of labels to packaging materials. Poor adhesion of labels to packaging materials. Introduction: The pharmaceutical industry relies heavily on precise labeling for product identification, regulatory compliance, and consumer safety. Labels on packaging materials convey critical information, including dosage instructions, expiration dates, and safety warnings. However, poor adhesion of these labels can compromise product…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule fill weight variations during long-term storage.

March 16, 2025 Admin

Inadequate systems for monitoring capsule fill weight variations during long-term storage. Inadequate Systems for Monitoring Capsule Fill Weight Variations During Long-Term Storage Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms, particularly capsules, is crucial. Capsules, whether hard or soft gelatin, are popular due to their ease of administration…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Loss of Moisture Control in Hygroscopic Tablet Storage

March 14, 2025 Admin

Troubleshooting Loss of Moisture Control in Hygroscopic Tablet Storage Troubleshooting Loss of Moisture Control in Hygroscopic Tablet Storage Introduction: In the pharmaceutical industry, maintaining the integrity of solid dosage forms, particularly hygroscopic tablets, is crucial. Hygroscopic tablets are designed to absorb moisture from the environment, making them particularly vulnerable to degradation if not stored properly….

Solid Dosage form, Tablets

Poor reproducibility in stability data across multiple batches.

March 8, 2025 Admin

Poor reproducibility in stability data across multiple batches. Poor Reproducibility in Stability Data Across Multiple Batches Introduction: In the realm of pharmaceutical manufacturing, ensuring the stability of products is paramount. Stability data are crucial for determining the shelf life and storage conditions of pharmaceutical products, ensuring they remain safe and effective for patients throughout their…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate methods for monitoring capsule brittleness under low humidity conditions.

March 6, 2025 Admin

Inadequate methods for monitoring capsule brittleness under low humidity conditions. Inadequate Methods for Monitoring Capsule Brittleness Under Low Humidity Conditions Introduction: Capsules, both hard and soft gelatin, are a prevalent form of solid oral dosage forms in the pharmaceutical industry. Ensuring their integrity and efficacy is crucial for therapeutic effectiveness. One of the significant challenges…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms