Tag: Stability testing

High variability in stability data for oil-filled capsules.

March 12, 2025 Admin

High variability in stability data for oil-filled capsules. High variability in stability data for oil-filled capsules. Introduction: In the pharmaceutical industry, maintaining the stability of medicinal products is crucial to ensure their safety, efficacy, and quality over their shelf life. Among various dosage forms, oil-filled capsules—encompassing both hard and soft gelatin variants—present unique challenges in…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Documentation Errors in Stability Testing Records

March 12, 2025 Admin

Managing Documentation Errors in Stability Testing Records Managing Documentation Errors in Stability Testing Records Introduction: In the pharmaceutical industry, stability testing is a critical process that ensures the safety, efficacy, and quality of drug products over their shelf life. Proper documentation of stability testing records is vital for maintaining compliance with regulatory standards such as…

Solid Dosage form, Tablets

Managing Failures in Stress Testing for Controlled Release Tablets

March 12, 2025 Admin

Managing Failures in Stress Testing for Controlled Release Tablets Managing Failures in Stress Testing for Controlled Release Tablets Introduction: In the pharmaceutical industry, controlled release tablets play a pivotal role in ensuring the precise delivery of active pharmaceutical ingredients (APIs) over an extended period. These tablets are designed to optimize therapeutic efficacy and improve patient…

Solid Dosage form, Tablets

Preventing Tablet Damage During Drop Testing of Blister Packs

March 12, 2025 Admin

Preventing Tablet Damage During Drop Testing of Blister Packs Preventing Tablet Damage During Drop Testing of Blister Packs Introduction: In the pharmaceutical industry, ensuring the integrity of solid dosage forms such as tablets is crucial to maintaining product efficacy and patient safety. Blister packs are a common packaging solution designed to protect tablets from environmental…

Solid Dosage form, Tablets

Managing Failures in Stress Tests for Sustained Release Tablets

March 12, 2025 Admin

Managing Failures in Stress Tests for Sustained Release Tablets Managing Failures in Stress Tests for Sustained Release Tablets Introduction: Sustained release tablets are critical in modern pharmaceutical formulations, offering controlled drug release over extended periods. These tablets enhance patient compliance by reducing the frequency of dosing and maintaining therapeutic drug levels. However, ensuring their effectiveness…

Solid Dosage form, Tablets

Problems with standardizing temperature conditions during testing.

March 11, 2025 Admin

Problems with standardizing temperature conditions during testing. Problems with Standardizing Temperature Conditions During Testing Introduction: In the pharmaceutical industry, maintaining consistent and controlled testing environments is crucial for ensuring the quality, efficacy, and safety of drug products. This is particularly true for solid oral dosage forms such as capsules, both hard and soft gelatin, where…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Issues in Stability Testing for Immediate Release Tablets

March 11, 2025 Admin

Resolving Issues in Stability Testing for Immediate Release Tablets Resolving Issues in Stability Testing for Immediate Release Tablets Introduction: Stability testing is a critical component in the development and lifecycle management of pharmaceutical products. For immediate release tablets, which are designed to disintegrate and release their active ingredients promptly upon administration, ensuring stability is paramount….

Solid Dosage form, Tablets

Problems with ensuring consistent drug release profiles during stability studies.

March 11, 2025 Admin

Problems with ensuring consistent drug release profiles during stability studies. Problems with ensuring consistent drug release profiles during stability studies. Introduction: In the pharmaceutical industry, stability studies are essential for ensuring that a drug maintains its intended efficacy, safety, and quality over time. These studies are particularly critical for solid oral dosage forms, such as…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Heat Sensitivity of APIs During Validation of Coated Tablets

March 10, 2025 Admin

Addressing Heat Sensitivity of APIs During Validation of Coated Tablets Addressing Heat Sensitivity of APIs During Validation of Coated Tablets Introduction: The pharmaceutical industry continuously strives to enhance the efficacy, stability, and safety of drug products. One of the critical aspects of drug formulation is the management of active pharmaceutical ingredients (APIs) that exhibit sensitivity…

Solid Dosage form, Tablets

Inadequate validation of capsule performance under UV light exposure.

March 10, 2025 Admin

Inadequate validation of capsule performance under UV light exposure. Inadequate validation of capsule performance under UV light exposure. Introduction: The pharmaceutical industry is tasked with ensuring the safety, efficacy, and stability of its products. Among the multitude of factors that can affect drug stability, exposure to ultraviolet (UV) light is a significant concern, particularly for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High rejection rates due to brittleness in capsule shells after stability testing.

March 10, 2025 Admin

High rejection rates due to brittleness in capsule shells after stability testing. High rejection rates due to brittleness in capsule shells after stability testing. Introduction: The pharmaceutical industry is ever-evolving, with a constant push towards enhancing the quality and efficacy of drug delivery systems. Capsules, both hard and soft gelatin, play a pivotal role in…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Challenges in Coating Integrity Tests During Stability Studies

March 9, 2025 Admin

Addressing Challenges in Coating Integrity Tests During Stability Studies Addressing Challenges in Coating Integrity Tests During Stability Studies Introduction: In the pharmaceutical industry, the stability of a drug product is paramount for ensuring its safety, efficacy, and quality throughout its shelf life. One crucial aspect of this stability is the integrity of tablet coatings. Coating…

Solid Dosage form, Tablets