Tag: solid oral dosage forms

Poor validation of capsule disintegration testing for gelatin-free capsules.

March 17, 2025 Admin

Poor validation of capsule disintegration testing for gelatin-free capsules. Poor validation of capsule disintegration testing for gelatin-free capsules. Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of oral dosage forms is paramount. Capsules, both hard and soft gelatin, have been widely used due to their ability to encapsulate a variety of formulations. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in testing for uniformity of multi-particulate capsule formulations.

March 16, 2025 Admin

Difficulty in testing for uniformity of multi-particulate capsule formulations. Difficulty in testing for uniformity of multi-particulate capsule formulations. Introduction: In the pharmaceutical industry, ensuring the uniformity of dosage units is crucial for both efficacy and safety. Multi-particulate capsule formulations are increasingly popular due to their flexibility in delivering a consistent dose of active pharmaceutical ingredients…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in recovery rates for rinse sampling validation.

March 15, 2025 Admin

Poor reproducibility in recovery rates for rinse sampling validation. Poor reproducibility in recovery rates for rinse sampling validation. Introduction: In the pharmaceutical industry, maintaining rigorous standards for cleanliness and contamination control is paramount. Rinse sampling validation is a critical component of this process, ensuring that manufacturing equipment is adequately cleaned between batches. However, achieving consistent…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving uniform distribution of capsules within packs.

March 13, 2025 Admin

Difficulty in achieving uniform distribution of capsules within packs. Difficulty in Achieving Uniform Distribution of Capsules within Packs Introduction: The pharmaceutical industry is continually evolving, driven by the need to ensure product efficacy, safety, and consumer satisfaction. Solid oral dosage forms, particularly capsules, are a staple in the industry due to their ease of administration…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor correlation between accelerated and real-time stability results.

March 12, 2025 Admin

Poor correlation between accelerated and real-time stability results. Poor correlation between accelerated and real-time stability results. Introduction: Stability testing is an essential component of the pharmaceutical development process. It ensures that a drug product maintains its intended physical, chemical, microbiological, and therapeutic properties throughout its shelf life. Accelerated stability testing and real-time stability testing are…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High variability in results of content uniformity testing for low-dose drugs.

March 8, 2025 Admin

High variability in results of content uniformity testing for low-dose drugs. High Variability in Results of Content Uniformity Testing for Low-Dose Drugs Introduction: The pharmaceutical industry is tasked with the critical role of ensuring that every dose of medication administered to patients is safe, effective, and of high quality. One of the major quality control…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating cleaning processes for high-viscosity formulations.

March 2, 2025 Admin

Difficulty in validating cleaning processes for high-viscosity formulations. Difficulty in Validating Cleaning Processes for High-Viscosity Formulations Introduction: In the pharmaceutical industry, maintaining the integrity and quality of solid oral dosage forms, such as capsules, is of paramount importance. Among these, high-viscosity formulations present unique challenges in the cleaning process validation. This blog delves into the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms