Tag: solid dosage forms

Addressing Core Crumbling in Multi-Layer Tablet Compression

March 20, 2025 Admin

Addressing Core Crumbling in Multi-Layer Tablet Compression Addressing Core Crumbling in Multi-Layer Tablet Compression Introduction: The pharmaceutical industry constantly strives to improve the quality and efficacy of solid dosage forms, particularly tablets. Multi-layer tablets have gained popularity due to their ability to deliver more than one active ingredient with different release profiles. However, the manufacturing…

Solid Dosage form, Tablets

Ensuring Consistency in Coating Thickness Measurements During QA Testing

March 20, 2025 Admin

Ensuring Consistency in Coating Thickness Measurements During QA Testing Ensuring Consistency in Coating Thickness Measurements During QA Testing Introduction: In the realm of pharmaceutical manufacturing, ensuring the consistency and quality of tablet coatings is crucial. Coating not only enhances the aesthetic appeal but also plays a significant role in controlling the release of active ingredients,…

Solid Dosage form, Tablets

Addressing Over-Sensitivity to Humidity in Hygroscopic Tablets

March 19, 2025 Admin

Addressing Over-Sensitivity to Humidity in Hygroscopic Tablets Addressing Over-Sensitivity to Humidity in Hygroscopic Tablets Introduction: In the pharmaceutical industry, the stability of solid dosage forms like tablets is paramount to ensuring efficacy and safety. Hygroscopic tablets, which readily absorb moisture from their environment, present unique challenges in terms of formulation, manufacturing, and storage. Over-sensitivity to…

Solid Dosage form, Tablets

Addressing Granule Segregation During Roller Compaction

March 19, 2025 Admin

Addressing Granule Segregation During Roller Compaction Addressing Granule Segregation During Roller Compaction Introduction: In the realm of pharmaceutical manufacturing, ensuring the uniformity and quality of solid dosage forms such as tablets is crucial. Roller compaction is a dry granulation process commonly used to improve the flow properties and compressibility of powders. However, one of the…

Solid Dosage form, Tablets

Challenges in maintaining uniform mixing of multi-component powder blends.

March 19, 2025 Admin

Challenges in maintaining uniform mixing of multi-component powder blends. Challenges in maintaining uniform mixing of multi-component powder blends. Introduction: In the pharmaceutical industry, ensuring the uniform mixing of multi-component powder blends is crucial for the efficacy and safety of solid oral dosage forms, such as capsules. Uniformity in blending impacts the quality and consistency of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Ensuring Consistency in Content Uniformity Tests Across Batches

March 19, 2025 Admin

Ensuring Consistency in Content Uniformity Tests Across Batches Ensuring Consistency in Content Uniformity Tests Across Batches Introduction: In the pharmaceutical industry, the consistency of content uniformity tests across batches is pivotal to ensuring the safety and efficacy of solid dosage forms, particularly tablets. Content uniformity is a critical quality attribute that determines whether each tablet…

Solid Dosage form, Tablets

Addressing Poor Adhesion in Enteric Coating Processes

March 18, 2025 Admin

Addressing Poor Adhesion in Enteric Coating Processes Addressing Poor Adhesion in Enteric Coating Processes Introduction: Enteric coating is a crucial process in the pharmaceutical industry, designed to ensure that tablets withstand the acidic environment of the stomach and release their active ingredients in the more neutral pH of the intestine. However, poor adhesion during the…

Solid Dosage form, Tablets

Avoiding Over-Sensitivity to Moisture in Hygroscopic Tablets

March 18, 2025 Admin

Avoiding Over-Sensitivity to Moisture in Hygroscopic Tablets Avoiding Over-Sensitivity to Moisture in Hygroscopic Tablets Introduction: In the world of pharmaceuticals, the stability and efficacy of tablets are of utmost importance. Hygroscopic tablets, which have a tendency to absorb moisture from the environment, pose unique challenges in maintaining their integrity and functionality. Moisture sensitivity can lead…

Solid Dosage form, Tablets

Managing Fines Generation During Compression of Immediate Release Tablets

March 17, 2025 Admin

Managing Fines Generation During Compression of Immediate Release Tablets Managing Fines Generation During Compression of Immediate Release Tablets Introduction: In the pharmaceutical industry, the production of immediate-release tablets is a crucial process that requires meticulous attention to detail. One of the significant challenges faced during the tablet manufacturing process is the generation of fines. Fines…

Solid Dosage form, Tablets

Preventing Layer Cracking in Multi-Layer Tablets During Storage

March 17, 2025 Admin

Preventing Layer Cracking in Multi-Layer Tablets During Storage Preventing Layer Cracking in Multi-Layer Tablets During Storage Introduction: Multi-layer tablets are an increasingly popular pharmaceutical dosage form due to their ability to deliver multiple active ingredients with different release profiles in a single dosage unit. Despite their benefits, these tablets are susceptible to layer cracking during…

Solid Dosage form, Tablets

Achieving Uniform Blend Distribution in Blending Machines

March 17, 2025 Admin

Achieving Uniform Blend Distribution in Blending Machines Achieving Uniform Blend Distribution in Blending Machines Introduction: In the pharmaceutical industry, ensuring the uniform distribution of active pharmaceutical ingredients (APIs) and excipients in solid dosage forms is critical for product efficacy, safety, and quality. Blending is a key process in tablet manufacturing, where achieving uniform blend distribution…

Solid Dosage form, Tablets

Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment

March 17, 2025 Admin

Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment Introduction: In the pharmaceutical manufacturing industry, ensuring the adequacy of compressed air pressure for granulation equipment is crucial for producing high-quality solid dosage forms. Granulation is a key process in tablet production, impacting the uniformity, compressibility, and…

Solid Dosage form, Tablets