Tag: solid dosage forms

Addressing Over-Drying in Sugar-Coated Tablets During Curing

March 27, 2025 Admin

Addressing Over-Drying in Sugar-Coated Tablets During Curing Addressing Over-Drying in Sugar-Coated Tablets During Curing Introduction: Sugar-coating is an essential phase in the production of tablets, offering not only aesthetic appeal but also protection from environmental factors. However, one of the prevalent challenges during the sugar-coating process is over-drying, which can compromise the integrity and effectiveness…

Solid Dosage form, Tablets

Managing Over-Sensitivity to Humidity in Hygroscopic Tablets During Production

March 27, 2025 Admin

Managing Over-Sensitivity to Humidity in Hygroscopic Tablets During Production Managing Over-Sensitivity to Humidity in Hygroscopic Tablets During Production Introduction: Hygroscopic tablets are an essential component of the pharmaceutical industry, offering a convenient and effective means of delivering medication to patients. However, their production poses significant challenges due to their sensitivity to humidity. Excess moisture can…

Solid Dosage form, Tablets

Managing Powder Bridging in Tablet Press Hoppers

March 26, 2025 Admin

Managing Powder Bridging in Tablet Press Hoppers Managing Powder Bridging in Tablet Press Hoppers Introduction: In the realm of pharmaceutical manufacturing, the production of tablets represents a critical and intricate process. Among the many challenges faced in this domain, powder bridging within tablet press hoppers is a significant concern. This issue can lead to inconsistent…

Solid Dosage form, Tablets

Root Cause Analysis of Failures in Weight Uniformity Tests

March 26, 2025 Admin

Root Cause Analysis of Failures in Weight Uniformity Tests Root Cause Analysis of Failures in Weight Uniformity Tests Introduction: In the realm of pharmaceutical manufacturing, ensuring the consistency and quality of dosage forms is paramount. One of the critical quality control tests for solid dosage forms, specifically tablets, is the weight uniformity test. This test…

Solid Dosage form, Tablets

Managing Powder Segregation in High-Speed Blending Equipment

March 25, 2025 Admin

Managing Powder Segregation in High-Speed Blending Equipment Managing Powder Segregation in High-Speed Blending Equipment Introduction: In the pharmaceutical industry, achieving uniformity in solid dosage forms is crucial for ensuring efficacy and patient safety. High-speed blending equipment is commonly used in the production of tablets to mix powdered ingredients. However, one of the significant challenges in…

Solid Dosage form, Tablets

Addressing Over-Lubrication in Powder Blends During Compression

March 25, 2025 Admin

Addressing Over-Lubrication in Powder Blends During Compression Addressing Over-Lubrication in Powder Blends During Compression Introduction: In the pharmaceutical industry, the production of high-quality tablets is pivotal. The tablet compression process is a critical phase where powder blends are transformed into solid dosage forms. However, one of the common challenges faced during this process is over-lubrication,…

Solid Dosage form, Tablets

Optimizing Compression Force for Extended Release Tablet Uniformity

March 25, 2025 Admin

Optimizing Compression Force for Extended Release Tablet Uniformity Optimizing Compression Force for Extended Release Tablet Uniformity Introduction: Extended release tablets are a vital component of modern pharmaceutical therapies, designed to release their active ingredients at a predetermined rate to maintain a consistent drug concentration in the bloodstream. Ensuring the uniformity of these tablets is crucial,…

Solid Dosage form, Tablets

Addressing Challenges in Process Validation for Immediate Release Tablets

March 24, 2025 Admin

Addressing Challenges in Process Validation for Immediate Release Tablets Addressing Challenges in Process Validation for Immediate Release Tablets Introduction: Immediate release tablets are a cornerstone in the pharmaceutical industry, known for their rapid disintegration and absorption properties, providing swift therapeutic effects. As the demand for these tablets continues to grow, ensuring their efficacy and safety…

Solid Dosage form, Tablets

Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers

March 24, 2025 Admin

Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers Introduction: In the pharmaceutical industry, enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral or alkaline environment of the intestine. This functionality is crucial for protecting active pharmaceutical ingredients (APIs) that are…

Solid Dosage form, Tablets

Real-Time Monitoring of Granulation Moisture Levels During Wet Granulation

March 23, 2025 Admin

Real-Time Monitoring of Granulation Moisture Levels During Wet Granulation Real-Time Monitoring of Granulation Moisture Levels During Wet Granulation Introduction: In the pharmaceutical industry, the manufacturing of solid dosage forms such as tablets often involves the process of wet granulation. This critical process ensures the homogeneity and compressibility of the drug mixture. One of the most…

Solid Dosage form, Tablets

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing

March 22, 2025 Admin

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Introduction: In the pharmaceutical industry, enteric-coated tablets play a crucial role in ensuring that active pharmaceutical ingredients (APIs) are delivered to the intestine, bypassing the acidic environment of the stomach. This not only protects the drug from…

Solid Dosage form, Tablets

Problems with ensuring consistent nitrogen distribution for capsule production.

March 21, 2025 Admin

Problems with ensuring consistent nitrogen distribution for capsule production. Problems with ensuring consistent nitrogen distribution for capsule production. Introduction: In the pharmaceutical industry, the production of solid oral dosage forms such as capsules is a complex process that requires meticulous attention to detail. Among the various factors that influence capsule quality, the consistent distribution of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms