Tag: solid dosage form challenges]

Managing Tablet Core Erosion in Enteric-Coated Tablets

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Managing Tablet Core Erosion in Enteric-Coated Tablets Managing Tablet Core Erosion in Enteric-Coated Tablets Introduction: Enteric-coated tablets represent a sophisticated drug delivery system designed to bypass the acidic environment of the stomach and to release their active ingredients in the more neutral pH of the intestines. This method of delivery is essential for drugs that…

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Solid Dosage form, Tablets

Troubleshooting Moisture Retention in Hygroscopic Tablet Coatings

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Troubleshooting Moisture Retention in Hygroscopic Tablet Coatings Troubleshooting Moisture Retention in Hygroscopic Tablet Coatings Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of solid dosage forms like tablets is paramount. Tablet coatings, especially those involving hygroscopic materials, play a crucial role in protecting the core from environmental factors such as moisture. However, moisture…

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Solid Dosage form, Tablets

Managing Non-Uniform API Distribution in Content Uniformity Tests

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Managing Non-Uniform API Distribution in Content Uniformity Tests Managing Non-Uniform API Distribution in Content Uniformity Tests Introduction: The uniform distribution of the Active Pharmaceutical Ingredient (API) in solid dosage forms, such as tablets, is a critical quality attribute in pharmaceutical manufacturing. The reliability of therapeutic outcomes and patient safety hinges on the consistent delivery of…

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Solid Dosage form, Tablets