Tag: Soft gelatin capsules

Inadequate methods for evaluating capsule dissolution in biorelevant media during stability studies.

April 9, 2025 Admin

Inadequate methods for evaluating capsule dissolution in biorelevant media during stability studies. Inadequate methods for evaluating capsule dissolution in biorelevant media during stability studies. Introduction: In the realm of pharmaceuticals, the dissolution testing of capsules is a critical parameter in ensuring the efficacy and safety of drug products. Evaluating capsule dissolution in biorelevant media during…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining proper storage conditions for packaging materials.

April 9, 2025 Admin

Difficulty in maintaining proper storage conditions for packaging materials. Difficulty in Maintaining Proper Storage Conditions for Packaging Materials Introduction: In the pharmaceutical industry, maintaining the integrity and efficacy of products is paramount. Packaging materials, particularly for solid oral dosage forms like capsules, play a critical role in protecting the product from environmental factors and ensuring…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in detecting microscopic defects in capsule shells.

April 9, 2025 Admin

Difficulty in detecting microscopic defects in capsule shells. Difficulty in Detecting Microscopic Defects in Capsule Shells Introduction: Capsules are one of the most popular solid oral dosage forms in the pharmaceutical industry, offering a convenient and effective means of drug delivery. However, maintaining the integrity and quality of capsule shells is crucial, as defects can…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating equipment for encapsulating semi-solid formulations.

April 8, 2025 Admin

Challenges in validating equipment for encapsulating semi-solid formulations. Challenges in validating equipment for encapsulating semi-solid formulations. Introduction: In the pharmaceutical industry, the encapsulation of semi-solid formulations presents unique challenges that require precise validation to ensure product efficacy and safety. Semi-solid formulations, often used for their controlled release properties and enhanced bioavailability, demand stringent equipment validation…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting microscopic cracks in gelatin shells.

April 8, 2025 Admin

Problems with detecting microscopic cracks in gelatin shells. Problems with Detecting Microscopic Cracks in Gelatin Shells Introduction: Gelatin capsules, both hard and soft, are integral to the pharmaceutical industry due to their effectiveness in encapsulating drugs and providing controlled release. However, ensuring the integrity of these capsules is critical, as even microscopic cracks in the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring capsule weight variation.

April 8, 2025 Admin

Poor reproducibility in monitoring capsule weight variation. Poor reproducibility in monitoring capsule weight variation. Introduction: Capsules, as solid oral dosage forms, play a critical role in the pharmaceutical industry due to their ease of administration, stability, and ability to encapsulate a variety of substances. However, ensuring consistent weight and content uniformity remains a significant challenge,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule drying processes for multi-component formulations.

April 8, 2025 Admin

Difficulty in validating capsule drying processes for multi-component formulations. Difficulty in validating capsule drying processes for multi-component formulations. Introduction: In the pharmaceutical industry, the production of solid oral dosage forms such as capsules is a complex process that requires precise control and validation. Capsules, whether hard or soft gelatin, are a popular choice due to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with validating capsule filling processes for hygroscopic powders.

April 8, 2025 Admin

Problems with validating capsule filling processes for hygroscopic powders. Problems with Validating Capsule Filling Processes for Hygroscopic Powders Introduction: In the pharmaceutical industry, encapsulation is a critical process that ensures the delivery of precise dosages in a patient-friendly form. Capsules, whether hard or soft gelatin, are popular due to their ease of administration and ability…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule transparency changes over time.

April 8, 2025 Admin

Inadequate systems for monitoring capsule transparency changes over time. Inadequate systems for monitoring capsule transparency changes over time. Introduction: In the realm of pharmaceuticals, maintaining the quality and integrity of solid oral dosage forms such as capsules is paramount. Capsules, both hard and soft gelatin, are popular due to their ease of administration and ability…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent calibration of capsule drying equipment.

April 7, 2025 Admin

Problems with ensuring consistent calibration of capsule drying equipment. Problems with ensuring consistent calibration of capsule drying equipment. Introduction: Capsule manufacturing is a critical component of the pharmaceutical industry, offering a convenient dosage form for a wide range of medications. Ensuring the quality and efficacy of these capsules involves numerous processes, among which drying plays…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring powder flow properties during encapsulation.

April 7, 2025 Admin

Poor reproducibility in monitoring powder flow properties during encapsulation. Poor reproducibility in monitoring powder flow properties during encapsulation. Introduction: In the pharmaceutical industry, encapsulation is a critical process for the manufacturing of solid oral dosage forms. The flow properties of powders are essential, as they determine the efficiency and consistency of the encapsulation process. Poor…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating cleaning procedures for non-aqueous formulations.

April 7, 2025 Admin

Difficulty in validating cleaning procedures for non-aqueous formulations. Difficulty in Validating Cleaning Procedures for Non-Aqueous Formulations Introduction: In the pharmaceutical industry, ensuring the cleanliness of manufacturing equipment is paramount to prevent cross-contamination and ensure product quality. This is especially critical when dealing with non-aqueous formulations, often used in the production of capsules, both hard and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms