Tag: Soft gelatin capsules

Difficulty in achieving consistent lubrication of filling equipment.

April 22, 2025 Admin

Difficulty in achieving consistent lubrication of filling equipment. Difficulty in Achieving Consistent Lubrication of Filling Equipment Introduction: In the pharmaceutical industry, maintaining efficient and consistent operations is critical to ensure product quality and regulatory compliance. One of the significant challenges faced by manufacturers of solid oral dosage forms, particularly capsules, is achieving consistent lubrication of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in detecting residual APIs on capsule filling equipment.

April 22, 2025 Admin

Difficulty in detecting residual APIs on capsule filling equipment. Difficulty in Detecting Residual APIs on Capsule Filling Equipment Introduction: The pharmaceutical industry is committed to ensuring the highest standards of quality and safety. One critical aspect of this is the effective cleaning of capsule filling equipment to prevent cross-contamination and ensure product purity. Residual Active…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring shell thickness for soft gelatin capsules.

April 22, 2025 Admin

Poor reproducibility in monitoring shell thickness for soft gelatin capsules. Poor reproducibility in monitoring shell thickness for soft gelatin capsules. Introduction: In the pharmaceutical industry, soft gelatin capsules play a critical role as a popular dosage form due to their versatility and patient compliance. However, ensuring the quality and consistency of these capsules is crucial,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining consistent capsule appearance during production.

April 21, 2025 Admin

Difficulty in maintaining consistent capsule appearance during production. Difficulty in maintaining consistent capsule appearance during production. Introduction: Capsule appearance is a critical quality attribute in pharmaceutical manufacturing. The appearance not only reflects the aesthetic qualities of the product but also its safety, efficacy, and compliance with regulatory standards. Inconsistent capsule appearance during production can lead…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in assessing the stability of capsules containing low-dose APIs.

April 21, 2025 Admin

Difficulty in assessing the stability of capsules containing low-dose APIs. Difficulty in assessing the stability of capsules containing low-dose APIs. Introduction: In the pharmaceutical industry, ensuring the stability of drug products is paramount, particularly when dealing with capsules containing low-dose Active Pharmaceutical Ingredients (APIs). Stability refers to the ability of a drug product to maintain…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in maintaining proper records for batch-specific quality deviations.

April 21, 2025 Admin

Challenges in maintaining proper records for batch-specific quality deviations. Challenges in maintaining proper records for batch-specific quality deviations Introduction: In the pharmaceutical industry, maintaining precise and thorough records of batch-specific quality deviations is vital for ensuring product safety and regulatory compliance. These records are essential for tracking the history of a product, identifying the root…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with validating gelatin solution cooling rates during processing.

April 21, 2025 Admin

Problems with validating gelatin solution cooling rates during processing. Problems with Validating Gelatin Solution Cooling Rates During Processing Introduction: In the pharmaceutical industry, the production of gelatin capsules, both hard and soft, plays a critical role. These capsules are popular due to their ease of use and ability to encapsulate a wide range of pharmaceutical…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating cleaning cycles for capsule sealing rollers.

April 20, 2025 Admin

Difficulty in validating cleaning cycles for capsule sealing rollers. Difficulty in validating cleaning cycles for capsule sealing rollers. Introduction: In the pharmaceutical industry, ensuring the hygiene and cleanliness of equipment used in manufacturing processes is paramount to maintaining product quality and patient safety. One critical aspect of this is the validation of cleaning cycles for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring proper cleaning of capsule sealing equipment.

April 20, 2025 Admin

Problems with ensuring proper cleaning of capsule sealing equipment. Problems with ensuring proper cleaning of capsule sealing equipment. Introduction: The pharmaceutical industry is synonymous with precision, safety, and quality. Among the various processes, the sealing of capsules—both hard and soft gelatin—holds a pivotal role. Ensuring the cleanliness of capsule sealing equipment is crucial not only…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor correlation between laboratory and field stability data for capsules.

April 20, 2025 Admin

Poor correlation between laboratory and field stability data for capsules. Poor correlation between laboratory and field stability data for capsules. Introduction: In the pharmaceutical industry, stability testing is a critical component that ensures the safety, efficacy, and quality of drug products throughout their shelf life. Capsules, both hard and soft gelatin, are popular solid oral…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in implementing robust quality audits for capsule production.

April 20, 2025 Admin

Challenges in implementing robust quality audits for capsule production. Challenges in implementing robust quality audits for capsule production. Introduction: In the ever-evolving pharmaceutical industry, maintaining stringent quality standards is paramount, especially when it comes to the production of capsules. Capsules, whether hard or soft gelatin, are among the most widely used solid oral dosage forms,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in capsule shell thickness validation data.

April 19, 2025 Admin

Poor reproducibility in capsule shell thickness validation data. Poor reproducibility in capsule shell thickness validation data. Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms is paramount. Capsules, particularly hard and soft gelatin variants, are widely used due to their ability to deliver precise doses and protect sensitive ingredients….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms