Tag: Soft gelatin capsules

Difficulty in ensuring compliance with capsule-specific pharmacopeial standards.

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Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Introduction: In the pharmaceutical industry, ensuring compliance with pharmacopeial standards is crucial for the safety and efficacy of drug products. Capsules, both hard and soft gelatin varieties, are a popular dosage form due to their convenience and ability to…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor correlation between in vitro dissolution and stability data.

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Poor correlation between in vitro dissolution and stability data. Poor correlation between in vitro dissolution and stability data. Introduction: In the pharmaceutical industry, the correlation between in vitro dissolution and stability data is pivotal for ensuring the efficacy and safety of solid oral dosage forms, particularly capsules. Dissolution testing is a key quality control measure…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule integrity for long-term storage conditions.

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Difficulty in validating capsule integrity for long-term storage conditions. Difficulty in validating capsule integrity for long-term storage conditions. Introduction: In the pharmaceutical industry, ensuring the integrity of capsules over their shelf life is paramount. Capsules, whether hard or soft gelatin, are a preferred dosage form due to their ease of administration and ability to encapsulate…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule weight variation for powders with low bulk density.

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Poor validation of capsule weight variation for powders with low bulk density. Poor validation of capsule weight variation for powders with low bulk density. Introduction: In the pharmaceutical industry, the formulation and manufacture of capsules are crucial for ensuring patient safety and therapeutic efficacy. Capsules, particularly solid oral dosage forms, remain a popular choice due…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule sealing for high-viscosity formulations.

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Difficulty in validating capsule sealing for high-viscosity formulations. Difficulty in Validating Capsule Sealing for High-Viscosity Formulations Introduction: In the pharmaceutical industry, the development and manufacturing of solid oral dosage forms, specifically capsules, play a crucial role in delivering medications effectively to patients. Capsules, particularly those filled with high-viscosity formulations, present unique challenges in sealing validation….

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring cross-linking in gelatin shells.

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Inadequate systems for monitoring cross-linking in gelatin shells. Inadequate Systems for Monitoring Cross-Linking in Gelatin Shells Introduction: In the pharmaceutical industry, gelatin capsules are a popular choice for encapsulating a wide range of medications due to their ease of use, consumer preference, and bioavailability. However, one of the critical quality concerns associated with gelatin capsules,…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule weight loss due to evaporation.

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Inadequate systems for monitoring capsule weight loss due to evaporation. Inadequate Systems for Monitoring Capsule Weight Loss Due to Evaporation Introduction: Capsules, both hard and soft gelatin, are among the most popular solid oral dosage forms in the pharmaceutical industry, renowned for their ease of administration and ability to encapsulate a wide range of formulations….

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring consistent capsule appearance across validation batches.

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Difficulty in ensuring consistent capsule appearance across validation batches. Difficulty in ensuring consistent capsule appearance across validation batches Introduction: In the pharmaceutical industry, ensuring the consistent appearance of capsules across validation batches is pivotal for maintaining product quality and consumer trust. Capsules, whether hard or soft gelatin, must meet stringent aesthetic standards to ensure they…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating cleaning procedures for aqueous-based soft gelatin formulations.

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Difficulty in validating cleaning procedures for aqueous-based soft gelatin formulations. Difficulty in validating cleaning procedures for aqueous-based soft gelatin formulations. Introduction: In the pharmaceutical industry, maintaining strict hygiene and cleanliness standards is crucial, especially in the production of solid oral dosage forms such as capsules. Among these, aqueous-based soft gelatin formulations present unique challenges in…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining consistent quality across different capsule sizes.

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Problems with maintaining consistent quality across different capsule sizes. Problems with Maintaining Consistent Quality Across Different Capsule Sizes Introduction: Capsules, both hard and soft gelatin, remain a cornerstone of pharmaceutical delivery systems, offering precise dosage and ease of consumption. However, maintaining consistent quality across various capsule sizes presents a unique set of challenges. This article…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of temperature sensors in capsule drying ovens.

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Poor validation of temperature sensors in capsule drying ovens. Poor validation of temperature sensors in capsule drying ovens. Introduction: Temperature control is a critical aspect of pharmaceutical manufacturing, especially in the drying of capsules. Accurate temperature monitoring ensures the quality and efficacy of both hard and soft gelatin capsules. However, poor validation of temperature sensors…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for verifying cleaning agent effectiveness for lipid residues.

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Inadequate systems for verifying cleaning agent effectiveness for lipid residues. Inadequate systems for verifying cleaning agent effectiveness for lipid residues. Introduction: In the pharmaceutical industry, the effectiveness of cleaning agents in removing lipid residues is crucial, particularly in the production of solid oral dosage forms like capsules. Inadequate cleaning can lead to cross-contamination, affecting product…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms