Tag: Soft gelatin capsules

High variability in content uniformity testing for multi-drug capsules.

March 18, 2025 Admin

High variability in content uniformity testing for multi-drug capsules. High Variability in Content Uniformity Testing for Multi-Drug Capsules Introduction: Content uniformity is a critical quality attribute in the manufacturing of pharmaceuticals, ensuring that each dose in a batch contains the intended amount of active pharmaceutical ingredients (APIs). In the context of multi-drug capsules, achieving content…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in maintaining proper alignment of capsule caps and bodies.

March 17, 2025 Admin

Challenges in maintaining proper alignment of capsule caps and bodies. Challenges in maintaining proper alignment of capsule caps and bodies. Introduction: In the realm of pharmaceutical manufacturing, the production of solid oral dosage forms, specifically capsules, plays a pivotal role. Capsules, whether hard or soft gelatin, offer a versatile and efficient method for delivering medication….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Lack of automation in monitoring capsule defects during production.

March 17, 2025 Admin

Lack of automation in monitoring capsule defects during production. Lack of automation in monitoring capsule defects during production. Introduction: In the pharmaceutical industry, the production of solid oral dosage forms, such as capsules, is a critical segment that demands precision and accuracy. Hard and soft gelatin capsules are widely used due to their convenience and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining accurate logs for temperature and humidity controls.

March 17, 2025 Admin

Difficulty in maintaining accurate logs for temperature and humidity controls. Difficulty in Maintaining Accurate Logs for Temperature and Humidity Controls Introduction: In the pharmaceutical industry, maintaining precise environmental controls is crucial, especially for solid oral dosage forms like capsules. Both hard and soft gelatin capsules are sensitive to temperature and humidity fluctuations, which can affect…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule disintegration testing for gelatin-free capsules.

March 17, 2025 Admin

Poor validation of capsule disintegration testing for gelatin-free capsules. Poor validation of capsule disintegration testing for gelatin-free capsules. Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of oral dosage forms is paramount. Capsules, both hard and soft gelatin, have been widely used due to their ability to encapsulate a variety of formulations. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule defect trends over time.

March 16, 2025 Admin

Inadequate systems for monitoring capsule defect trends over time. Inadequate systems for monitoring capsule defect trends over time. Introduction: The pharmaceutical industry is under constant pressure to maintain high standards of quality and safety, particularly when it comes to solid oral dosage forms such as capsules. Capsules, which can be either hard or soft gelatin,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in testing for uniformity of multi-particulate capsule formulations.

March 16, 2025 Admin

Difficulty in testing for uniformity of multi-particulate capsule formulations. Difficulty in testing for uniformity of multi-particulate capsule formulations. Introduction: In the pharmaceutical industry, ensuring the uniformity of dosage units is crucial for both efficacy and safety. Multi-particulate capsule formulations are increasingly popular due to their flexibility in delivering a consistent dose of active pharmaceutical ingredients…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule filling processes for multi-layer capsules.

March 16, 2025 Admin

Difficulty in validating capsule filling processes for multi-layer capsules. Difficulty in Validating Capsule Filling Processes for Multi-layer Capsules Introduction: In the ever-evolving pharmaceutical industry, capsule formulations have become a pivotal aspect of oral dosage forms. Multi-layer capsules, offering innovative solutions for drug release, combination therapies, and patient compliance, are gaining popularity. However, the complexity of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining proper alignment of carton inserts.

March 15, 2025 Admin

Difficulty in maintaining proper alignment of carton inserts. Difficulty in maintaining proper alignment of carton inserts Introduction: In the pharmaceutical industry, the proper alignment of carton inserts plays a crucial role in ensuring that medications are packaged correctly and are user-friendly for healthcare providers and patients. Carton inserts provide necessary information about the medication, including…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with monitoring moisture migration within capsule shells.

March 15, 2025 Admin

Problems with monitoring moisture migration within capsule shells. Problems with Monitoring Moisture Migration Within Capsule Shells Introduction: In the pharmaceutical industry, ensuring the integrity and stability of solid oral dosage forms is paramount. Capsules, whether hard or soft gelatin, are widely used due to their ease of administration and ability to encapsulate a variety of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in implementing continuous quality improvement initiatives.

March 15, 2025 Admin

Challenges in implementing continuous quality improvement initiatives. Challenges in Implementing Continuous Quality Improvement Initiatives Introduction: The pharmaceutical industry is constantly evolving, driven by innovation, stringent regulatory requirements, and the need for consistent quality. Continuous Quality Improvement (CQI) initiatives are pivotal in ensuring that pharmaceutical companies stay competitive while meeting regulatory standards and improving patient outcomes….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in measuring residual moisture in soft gelatin capsules.

March 15, 2025 Admin

Challenges in measuring residual moisture in soft gelatin capsules. Challenges in measuring residual moisture in soft gelatin capsules. Introduction: The pharmaceutical industry is constantly evolving, with a focus on precision, quality, and compliance. Soft gelatin capsules, widely used for their ease of consumption and ability to encapsulate both aqueous and oily solutions, are highly sensitive…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms