Tag: Regulatory compliance

Troubleshooting Failures in Cleaning Validation for Coating Equipment

June 1, 2025 Admin

Troubleshooting Failures in Cleaning Validation for Coating Equipment Troubleshooting Failures in Cleaning Validation for Coating Equipment Introduction: In the pharmaceutical industry, the cleaning validation of coating equipment is a critical process that ensures the safety and efficacy of drug products. Cleaning validation verifies that residues from the manufacturing process, including active pharmaceutical ingredients (APIs), excipients,…

Solid Dosage form, Tablets

Troubleshooting Over-Lubrication in Powder Blends During Compression Validation

June 1, 2025 Admin

Troubleshooting Over-Lubrication in Powder Blends During Compression Validation Troubleshooting Over-Lubrication in Powder Blends During Compression Validation Introduction: In the pharmaceutical industry, the production of tablets is a complex process that demands precision and careful attention to detail. One critical aspect of tablet manufacturing is the lubrication of powder blends, which facilitates the tablet compression process….

Solid Dosage form, Tablets

Managing Residue Build-Up in Spray Guns for Coating Equipment Cleaning Validation

May 31, 2025 Admin

Managing Residue Build-Up in Spray Guns for Coating Equipment Cleaning Validation Managing Residue Build-Up in Spray Guns for Coating Equipment Cleaning Validation Introduction: In the pharmaceutical industry, maintaining the integrity of coating equipment is vital for ensuring product quality and regulatory compliance. Spray guns, integral to the coating process, often face challenges related to residue…

Solid Dosage form, Tablets

Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets

May 31, 2025 Admin

Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, especially for coated tablets. It ensures that the drug releases its active ingredients at the intended rate and extent. However, calibration failures…

Solid Dosage form, Tablets

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets

May 31, 2025 Admin

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the integrity of film-coated tablets is a critical aspect of product quality and efficacy. Film coatings on tablets serve multiple purposes, including protection from environmental factors, masking unpleasant tastes,…

Solid Dosage form, Tablets

Validating Water Purification Systems for Tablet Manufacturing Processes

May 30, 2025 Admin

Validating Water Purification Systems for Tablet Manufacturing Processes Validating Water Purification Systems for Tablet Manufacturing Processes Introduction: In the pharmaceutical industry, water is not just an ingredient; it is a critical component in the manufacturing of tablets. The purity and quality of water used in tablet manufacturing are paramount, as they directly affect the safety…

Solid Dosage form, Tablets

Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress

May 30, 2025 Admin

Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress Addressing Cracking in Film Coatings of Extended Release Tablets Under Stress Introduction: Film coatings are a critical component in the development of extended-release tablets, playing an essential role in the control of drug release rates, protection of the drug from environmental factors, and improving…

Solid Dosage form, Tablets

Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation

May 29, 2025 Admin

Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation Introduction: In the pharmaceutical industry, precision in tablet manufacturing is paramount. Ensuring the accuracy of compression force sensors during tablet press validation is critical for maintaining the quality and uniformity of tablets. These sensors play…

Solid Dosage form, Tablets

Ensuring Alignment of Tablets in Blister Packs for Aesthetic Appeal

May 29, 2025 Admin

Ensuring Alignment of Tablets in Blister Packs for Aesthetic Appeal Ensuring Alignment of Tablets in Blister Packs for Aesthetic Appeal Introduction: In the competitive pharmaceutical market, aesthetics and functionality of packaging play a crucial role in consumer perception and product success. Ensuring the proper alignment of tablets within blister packs not only enhances visual appeal…

Solid Dosage form, Tablets

Validating Cleaning Protocols for High-Speed Compression Lines

May 28, 2025 Admin

Validating Cleaning Protocols for High-Speed Compression Lines Validating Cleaning Protocols for High-Speed Compression Lines Introduction: In the pharmaceutical industry, ensuring the cleanliness of equipment used in tablet production is crucial for maintaining product quality and safety. High-speed compression lines are integral to the efficient production of tablets, but they also pose significant challenges when it…

Solid Dosage form, Tablets

Troubleshooting Label Placement Accuracy on Tablet Bottles

May 28, 2025 Admin

Troubleshooting Label Placement Accuracy on Tablet Bottles Troubleshooting Label Placement Accuracy on Tablet Bottles Introduction: In the pharmaceutical industry, the accurate placement of labels on tablet bottles is crucial for ensuring product compliance, safety, and traceability. Labels provide essential information such as dosage instructions, expiration dates, and batch numbers. Any inaccuracies in label placement can…

Solid Dosage form, Tablets

Managing Failures in Process Validation for High-Speed Compression

May 27, 2025 Admin

Managing Failures in Process Validation for High-Speed Compression Managing Failures in Process Validation for High-Speed Compression Introduction: In the pharmaceutical industry, process validation is a critical component of quality assurance, particularly for high-speed compression in tablet manufacturing. This process ensures that tablets meet consistent standards for quality, safety, and efficacy. However, managing failures in process…

Solid Dosage form, Tablets