Tag: Quality control

Inadequate control over capsule component traceability.

April 26, 2025 Admin

Inadequate control over capsule component traceability. Inadequate control over capsule component traceability. Introduction: In the pharmaceutical industry, ensuring the traceability of capsule components is crucial for maintaining product quality, ensuring patient safety, and complying with regulatory standards. Traceability refers to the ability to track every ingredient and material used in the manufacturing of capsules, from…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Investigating Impact of Oxidative Stress on Coated Tablet Stability

April 25, 2025 Admin

Investigating Impact of Oxidative Stress on Coated Tablet Stability Investigating Impact of Oxidative Stress on Coated Tablet Stability Introduction: In the pharmaceutical industry, the stability of coated tablets is a critical factor in ensuring drug efficacy and safety over their shelf life. Coated tablets are designed to protect the active pharmaceutical ingredients (APIs) from environmental…

Solid Dosage form, Tablets

Challenges in validating nitrogen purity levels for capsule drying processes.

April 25, 2025 Admin

Challenges in validating nitrogen purity levels for capsule drying processes. Challenges in Validating Nitrogen Purity Levels for Capsule Drying Processes Introduction: In the pharmaceutical industry, maintaining the quality and integrity of solid oral dosage forms, such as capsules, is paramount. The drying process of capsules, whether hard or soft gelatin, is a critical step that…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for validating capsule appearance inspection processes.

April 24, 2025 Admin

Inadequate systems for validating capsule appearance inspection processes. Inadequate systems for validating capsule appearance inspection processes. Introduction: The pharmaceutical industry is marked by stringent quality requirements, particularly when it comes to solid oral dosage forms like capsules. A critical aspect of manufacturing is ensuring the appearance of capsules meets predefined standards, as this directly impacts…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in dissolution profiles for lipid-based capsules.

April 24, 2025 Admin

Poor reproducibility in dissolution profiles for lipid-based capsules. Poor reproducibility in dissolution profiles for lipid-based capsules. Introduction: Lipid-based capsules, encompassing both hard and soft gelatin varieties, are critical in the delivery of poorly water-soluble drugs. These formulations improve bioavailability, allowing for efficient drug release and absorption. However, achieving consistent dissolution profiles in lipid-based capsules poses…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring compliance with capsule-specific pharmacopeial standards.

April 24, 2025 Admin

Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Introduction: In the pharmaceutical industry, ensuring compliance with pharmacopeial standards is crucial for the safety and efficacy of drug products. Capsules, both hard and soft gelatin varieties, are a popular dosage form due to their convenience and ability to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Over-Drying Issues in Granulation During Validation Runs

April 24, 2025 Admin

Addressing Over-Drying Issues in Granulation During Validation Runs Addressing Over-Drying Issues in Granulation During Validation Runs Introduction: In the pharmaceutical industry, granulation is a critical step in the production of solid dosage forms such as tablets. It involves the agglomeration of powder particles to form granules, which enhance the flowability and compressibility of the powder,…

Solid Dosage form, Tablets

Preventing Seal Integrity Failures in Multi-Layer Blister Packs

April 23, 2025 Admin

Preventing Seal Integrity Failures in Multi-Layer Blister Packs Preventing Seal Integrity Failures in Multi-Layer Blister Packs Introduction: In the pharmaceutical industry, ensuring the integrity of packaging is paramount to safeguarding the efficacy and safety of medicinal products. Multi-layer blister packs are a popular choice due to their ability to protect sensitive pharmaceuticals from environmental factors…

Solid Dosage form, Tablets

Inadequate systems for monitoring capsule printing accuracy.

April 23, 2025 Admin

Inadequate systems for monitoring capsule printing accuracy. Inadequate Systems for Monitoring Capsule Printing Accuracy Introduction: In the pharmaceutical industry, ensuring the accuracy of capsule printing is crucial for maintaining drug safety, efficacy, and compliance with regulatory standards. Capsule printing serves as a vital method for product identification, distinguishing between different medications, and providing necessary information…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging

April 23, 2025 Admin

Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging Troubleshooting Poor Adhesion of Desiccants in Tablet Packaging Introduction: In the pharmaceutical industry, maintaining the stability and integrity of tablet formulations is crucial. Tablets are often sensitive to environmental conditions, particularly moisture, which can compromise their quality and efficacy. To mitigate this, desiccants are employed in tablet…

Solid Dosage form, Tablets

Problems with ensuring consistent cleaning of capsule printing heads.

April 23, 2025 Admin

Problems with ensuring consistent cleaning of capsule printing heads. Problems with Ensuring Consistent Cleaning of Capsule Printing Heads Introduction: In the pharmaceutical industry, capsule printing is a critical process that involves imprinting information, such as dosage details or branding, onto the surface of capsules. Maintaining the cleanliness of capsule printing heads is crucial to ensure…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in preventing contamination of capsule packs during sealing.

April 22, 2025 Admin

Difficulty in preventing contamination of capsule packs during sealing. Difficulty in preventing contamination of capsule packs during sealing. Introduction: In the pharmaceutical industry, ensuring the integrity and safety of products is paramount. Capsules, both hard and soft gelatin, are a popular solid oral dosage form due to their ease of administration and ability to mask…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms