Tag: Quality control

Poor reproducibility in validation results for air filtration systems.

March 3, 2025 Admin

Poor reproducibility in validation results for air filtration systems. Poor reproducibility in validation results for air filtration systems. Introduction: In the pharmaceutical industry, air filtration systems are crucial for maintaining cleanroom standards and ensuring the quality and safety of products, especially in the manufacturing of solid oral dosage forms like capsules. These systems are designed…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Coating Layer Delamination During Quality Testing

March 3, 2025 Admin

Addressing Coating Layer Delamination During Quality Testing Addressing Coating Layer Delamination During Quality Testing Introduction: Coating layer delamination in tablets is a critical issue in the pharmaceutical industry, impacting both product efficacy and patient safety. The coating on a tablet not only serves an aesthetic function but also plays a crucial role in controlling the…

Solid Dosage form, Tablets

Preventing Powder Loss During Compression in High-Speed Machines

March 2, 2025 Admin

Preventing Powder Loss During Compression in High-Speed Machines Preventing Powder Loss During Compression in High-Speed Machines Introduction: The pharmaceutical industry is renowned for its stringent quality standards, especially in the manufacturing of solid dosage forms like tablets. One critical aspect of tablet production is the compression process, which often faces the challenge of powder loss….

Solid Dosage form, Tablets

Managing Failures in Batch Sampling for Quality Assurance

March 2, 2025 Admin

Managing Failures in Batch Sampling for Quality Assurance Managing Failures in Batch Sampling for Quality Assurance Introduction: In the pharmaceutical industry, ensuring the quality of a product is paramount. Batch sampling plays a critical role in this process, providing a snapshot that represents the entire production batch. However, managing failures in batch sampling is crucial…

Solid Dosage form, Tablets

Validating Residual Solvent Control Measures in Coated Tablets

March 2, 2025 Admin

Validating Residual Solvent Control Measures in Coated Tablets Validating Residual Solvent Control Measures in Coated Tablets Introduction: Residual solvents are volatile chemicals used or produced in the manufacture of pharmaceutical substances, excipients, or in the preparation of drug products. Their presence in pharmaceuticals is a critical quality and safety concern, especially in coated tablets where…

Solid Dosage form, Tablets

Addressing Residual Solvent Issues in Compressed Air Lines for Enteric Tablets

March 2, 2025 Admin

Addressing Residual Solvent Issues in Compressed Air Lines for Enteric Tablets Addressing Residual Solvent Issues in Compressed Air Lines for Enteric Tablets Introduction: In the pharmaceutical industry, maintaining the purity and quality of solid dosage forms, particularly enteric tablets, is crucial. Enteric tablets, designed to withstand the acidic environment of the stomach and dissolve in…

Solid Dosage form, Tablets

Managing Punch Adhesion Issues in Tablet Pressing Operations

March 2, 2025 Admin

Managing Punch Adhesion Issues in Tablet Pressing Operations Managing Punch Adhesion Issues in Tablet Pressing Operations Introduction: The process of tablet pressing is a critical stage in the production of solid dosage forms. One of the common issues faced during this process is punch adhesion, which can significantly affect the quality and consistency of the…

Solid Dosage form, Tablets

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing

March 2, 2025 Admin

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Introduction: In the pharmaceutical industry, the aesthetic and functional integrity of sugar-coated tablets is paramount. The coating not only enhances the appearance but also affects consumer perception and compliance. However, during accelerated stability testing, a crucial phase…

Solid Dosage form, Tablets

Addressing Non-Uniform Temperature Mapping in Fluid Bed Dryers During Validation

March 1, 2025 Admin

Addressing Non-Uniform Temperature Mapping in Fluid Bed Dryers During Validation Addressing Non-Uniform Temperature Mapping in Fluid Bed Dryers During Validation Introduction: Fluid bed dryers are critical components in the pharmaceutical manufacturing process, particularly in the production of solid dosage forms such as tablets. The uniformity of temperature within these dryers is crucial to ensure product…

Solid Dosage form, Tablets

Developing Equipment Qualification Protocols for Tablet Compression Machines

March 1, 2025 Admin

Developing Equipment Qualification Protocols for Tablet Compression Machines Developing Equipment Qualification Protocols for Tablet Compression Machines Introduction: In the pharmaceutical industry, the production of tablets is a critical process that demands precision and adherence to stringent quality standards. Equipment qualification for tablet compression machines is a vital step to ensure that the machinery used in…

Solid Dosage form, Tablets

Addressing Calibration Failures in Temperature Sensors for Utility Validation

March 1, 2025 Admin

Addressing Calibration Failures in Temperature Sensors for Utility Validation Addressing Calibration Failures in Temperature Sensors for Utility Validation Introduction: In the pharmaceutical industry, maintaining precise environmental conditions is crucial for ensuring product efficacy and safety. Temperature sensors play a vital role in utility validation, monitoring, and controlling critical processes. Calibration failures in these sensors can…

Solid Dosage form, Tablets

Preventing Layer Separation in Multi-Layer Tablet Designs

March 1, 2025 Admin

Preventing Layer Separation in Multi-Layer Tablet Designs Preventing Layer Separation in Multi-Layer Tablet Designs Introduction: In the realm of pharmaceutical manufacturing, multi-layer tablets offer a sophisticated solution for delivering multiple active pharmaceutical ingredients (APIs) with distinct release profiles. However, this complexity introduces the critical challenge of preventing layer separation, a phenomenon that can compromise tablet…

Solid Dosage form, Tablets