Tag: Powder Flowability

Poor validation of capsule weight variation for powders with low bulk density.

April 23, 2025 Admin

Poor validation of capsule weight variation for powders with low bulk density. Poor validation of capsule weight variation for powders with low bulk density. Introduction: In the pharmaceutical industry, the formulation and manufacture of capsules are crucial for ensuring patient safety and therapeutic efficacy. Capsules, particularly solid oral dosage forms, remain a popular choice due…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring powder compaction during filling.

April 19, 2025 Admin

Difficulty in monitoring powder compaction during filling. Difficulty in Monitoring Powder Compaction During Filling Introduction: In the pharmaceutical industry, the precision of powder compaction during the filling process is crucial to ensure the quality and efficacy of solid oral dosage forms, such as hard and soft gelatin capsules. Monitoring powder compaction is a complex task,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Over-Lubrication in Powder Mixtures for Blending

March 21, 2025 Admin

Addressing Over-Lubrication in Powder Mixtures for Blending Addressing Over-Lubrication in Powder Mixtures for Blending Introduction: In the pharmaceutical industry, the formulation of solid dosage forms like tablets is a finely tuned process that requires precision and careful consideration of multiple variables. Among these, the use of lubricants in powder mixtures for blending is crucial to…

Solid Dosage form, Tablets

Controlling Agglomeration in Powder Blending for High-Speed Compression

March 21, 2025 Admin

Controlling Agglomeration in Powder Blending for High-Speed Compression Controlling Agglomeration in Powder Blending for High-Speed Compression Introduction: In the pharmaceutical industry, the process of powder blending is a critical step in the production of solid dosage forms, particularly tablets. High-speed compression demands a high level of powder homogeneity to ensure tablet consistency and efficacy. However,…

Solid Dosage form, Tablets

Managing Over-Compression in Tablets with High-Dose APIs

March 18, 2025 Admin

Managing Over-Compression in Tablets with High-Dose APIs Managing Over-Compression in Tablets with High-Dose APIs Introduction: The pharmaceutical industry is increasingly challenged with the development and manufacturing of tablets that contain high-dose Active Pharmaceutical Ingredients (APIs). While these tablets are crucial for ensuring therapeutic efficacy, they come with a unique set of challenges, particularly in terms…

Solid Dosage form, Tablets

Preventing Powder Sticking in Die Cavities During Compression

March 7, 2025 Admin

Preventing Powder Sticking in Die Cavities During Compression Preventing Powder Sticking in Die Cavities During Compression Introduction: In the realm of pharmaceutical manufacturing, tablet compression is a critical step that transforms powder blends into solid dosage forms. However, one common challenge faced during this process is the sticking of powder to the die cavities. This…

Solid Dosage form, Tablets