Tag: pharmaceutical troubleshooting]

Inadequate systems for detecting capsule discoloration under light exposure.

March 4, 2025 Admin

Inadequate systems for detecting capsule discoloration under light exposure. Inadequate systems for detecting capsule discoloration under light exposure. Introduction: Capsules, both hard and soft gelatin, are one of the most popular solid oral dosage forms in the pharmaceutical industry. However, they are not immune to challenges that can affect their quality and efficacy. One such…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Failures in Compressed Air Distribution for Coated Tablets

March 4, 2025 Admin

Troubleshooting Failures in Compressed Air Distribution for Coated Tablets Troubleshooting Failures in Compressed Air Distribution for Coated Tablets Introduction: In the pharmaceutical industry, the production of coated tablets is a sophisticated process that requires precision and adherence to strict quality standards. Compressed air plays a vital role in various stages of tablet manufacturing, including coating,…

Solid Dosage form, Tablets

Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing

March 4, 2025 Admin

Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Troubleshooting Brittleness in Multi-Layer Tablets During Quality Testing Introduction: Multi-layer tablets have emerged as a significant innovation in the pharmaceutical industry, offering the advantage of delivering multiple drugs or the same drug at different release rates within a single dosage form. However, one of the critical challenges…

Solid Dosage form, Tablets

Problems with validating capsule printing for transparent capsules.

March 4, 2025 Admin

Problems with validating capsule printing for transparent capsules. Problems with validating capsule printing for transparent capsules. Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form due to their versatility, ease of administration, and ability to encapsulate a variety of drug formulations. Among the different types of capsules, transparent capsules have gained…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting improper sealing in high-viscosity formulations.

March 4, 2025 Admin

Problems with detecting improper sealing in high-viscosity formulations. Problems with Detecting Improper Sealing in High-Viscosity Formulations Introduction: In pharmaceutical manufacturing, ensuring the integrity of solid oral dosage forms is paramount. Capsules, both hard and soft gelatin, are popular due to their versatility and patient compliance. However, when dealing with high-viscosity formulations, improper sealing poses significant…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Non-Uniform Coating in Irregular Tablet Shapes

March 3, 2025 Admin

Troubleshooting Non-Uniform Coating in Irregular Tablet Shapes Troubleshooting Non-Uniform Coating in Irregular Tablet Shapes Introduction: In the intricate world of pharmaceutical manufacturing, ensuring the uniformity of tablet coatings is paramount, particularly when dealing with irregular tablet shapes. These coatings are not just for aesthetic appeal; they serve critical functions such as protecting the tablet’s core,…

Solid Dosage form, Tablets

Managing Non-Uniform API Distribution in Content Uniformity Tests

March 3, 2025 Admin

Managing Non-Uniform API Distribution in Content Uniformity Tests Managing Non-Uniform API Distribution in Content Uniformity Tests Introduction: The uniform distribution of the Active Pharmaceutical Ingredient (API) in solid dosage forms, such as tablets, is a critical quality attribute in pharmaceutical manufacturing. The reliability of therapeutic outcomes and patient safety hinges on the consistent delivery of…

Solid Dosage form, Tablets

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets

March 3, 2025 Admin

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Introduction: In the pharmaceutical industry, maintaining product integrity and patient safety is paramount. One of the significant challenges faced by manufacturers is the risk of cross-contamination, especially when utilizing shared utility lines for coated tablets….

Solid Dosage form, Tablets

Addressing Coating Layer Delamination During Quality Testing

March 3, 2025 Admin

Addressing Coating Layer Delamination During Quality Testing Addressing Coating Layer Delamination During Quality Testing Introduction: Coating layer delamination in tablets is a critical issue in the pharmaceutical industry, impacting both product efficacy and patient safety. The coating on a tablet not only serves an aesthetic function but also plays a crucial role in controlling the…

Solid Dosage form, Tablets

Troubleshooting Failures in Residual Solvent Analysis for Utility Validation Studies

March 3, 2025 Admin

Troubleshooting Failures in Residual Solvent Analysis for Utility Validation Studies Troubleshooting Failures in Residual Solvent Analysis for Utility Validation Studies Introduction: In the pharmaceutical industry, ensuring the safety and efficacy of products is paramount. Residual solvent analysis plays a critical role in utility validation studies, which are essential to maintaining the integrity of solid dosage…

Solid Dosage form, Tablets

Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets

March 3, 2025 Admin

Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a time-tested pharmaceutical dosage form, favored for their aesthetic appeal, masking of unpleasant tastes, and protection of the core tablet. Achieving a uniformly coated product is critical not only for consumer acceptance but also for ensuring consistent…

Solid Dosage form, Tablets

Addressing Coating Delamination Issues During In-Process Quality Checks

March 2, 2025 Admin

Addressing Coating Delamination Issues During In-Process Quality Checks Addressing Coating Delamination Issues During In-Process Quality Checks Introduction: In the pharmaceutical industry, tablets are one of the most common solid dosage forms. The coating of these tablets plays a pivotal role not only in aesthetics but also in functionality, including protection from environmental conditions, masking taste,…

Solid Dosage form, Tablets