Tag: Pharmaceutical Science]

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing

June 5, 2025 Admin

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing Introduction: In the pharmaceutical industry, the aesthetic and functional integrity of sugar-coated tablets is paramount. The coating not only enhances the appearance but also affects consumer perception and compliance. However, during accelerated stability testing, a crucial phase…

Solid Dosage form, Tablets

Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions

May 18, 2025 Admin

Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions Introduction: Bilayer tablets are increasingly utilized in the pharmaceutical industry to deliver multiple drugs or different release profiles in a single dosage form. This innovative approach not only enhances patient compliance but also offers significant benefits in…

Solid Dosage form, Tablets

Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions

April 27, 2025 Admin

Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions Introduction: Sugar-coated tablets have long been a staple in pharmaceutical formulations, offering benefits such as masking unpleasant tastes, improving tablet appearance, and protecting active pharmaceutical ingredients (APIs) from environmental factors. However, they also present unique challenges, particularly…

Solid Dosage form, Tablets

Poor correlation between in vitro dissolution and stability data.

April 24, 2025 Admin

Poor correlation between in vitro dissolution and stability data. Poor correlation between in vitro dissolution and stability data. Introduction: In the pharmaceutical industry, the correlation between in vitro dissolution and stability data is pivotal for ensuring the efficacy and safety of solid oral dosage forms, particularly capsules. Dissolution testing is a key quality control measure…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in testing soft gelatin capsules with high oil content.

April 16, 2025 Admin

Challenges in testing soft gelatin capsules with high oil content. Challenges in testing soft gelatin capsules with high oil content Introduction: Soft gelatin capsules are a popular dosage form in the pharmaceutical industry, offering unique advantages such as improved bioavailability and patient compliance. However, when these capsules contain high oil content, they present significant challenges…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time

April 13, 2025 Admin

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, maintaining the potency of the Active Pharmaceutical Ingredient (API)…

Solid Dosage form, Tablets

Addressing Challenges in Friability Testing for High-Speed Compression Tablets

March 17, 2025 Admin

Addressing Challenges in Friability Testing for High-Speed Compression Tablets Addressing Challenges in Friability Testing for High-Speed Compression Tablets Introduction: In the pharmaceutical industry, tablets remain one of the most common dosage forms due to their convenience, stability, and ease of administration. However, ensuring the integrity and quality of tablets, especially those produced at high speed,…

Solid Dosage form, Tablets

Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets

March 11, 2025 Admin

Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets Introduction: The pharmaceutical industry continually strives to enhance the quality and efficacy of its products, with sustained release tablets playing a vital role in modern medicine. These tablets offer prolonged therapeutic effects, improving…

Solid Dosage form, Tablets

Managing Failure in Moisture Content Tests for Hygroscopic Tablets

March 10, 2025 Admin

Managing Failure in Moisture Content Tests for Hygroscopic Tablets Managing Failure in Moisture Content Tests for Hygroscopic Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of medicinal products is paramount. Hygroscopic tablets, which are prone to absorbing moisture from the environment, present unique challenges in this regard. Moisture content tests are critical…

Solid Dosage form, Tablets

Addressing Color Fading in Sugar-Coated Tablets During Accelerated Testing

March 2, 2025 Admin

Solid Dosage form, Tablets