Tag: pharmaceutical regulations

Managing API Degradation in Sugar-Coated Tablets During Stability Studies

June 4, 2025 Admin

Managing API Degradation in Sugar-Coated Tablets During Stability Studies Managing API Degradation in Sugar-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of a drug product throughout its shelf life is of paramount importance. Sugar-coated tablets, a popular dosage form due to their aesthetic appeal and ease of ingestion,…

Solid Dosage form, Tablets

Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets

June 2, 2025 Admin

Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets Introduction: In the pharmaceutical industry, multi-layer tablets are gaining prominence due to their ability to deliver multiple drugs or achieve controlled release profiles. However, these complex formulations often face challenges, particularly with the adherence of coating layers. Ensuring that…

Solid Dosage form, Tablets

Preventing Color Fading in Sugar-Coated Tablets During Packaging

June 1, 2025 Admin

Preventing Color Fading in Sugar-Coated Tablets During Packaging Preventing Color Fading in Sugar-Coated Tablets During Packaging Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, providing an effective way to mask the taste of medication while enhancing its aesthetic appeal. However, maintaining the vibrant color of these tablets during packaging and storage is…

Solid Dosage form, Tablets

Troubleshooting Failures in Equipment Calibration for Weight Variation Control

May 22, 2025 Admin

Troubleshooting Failures in Equipment Calibration for Weight Variation Control Troubleshooting Failures in Equipment Calibration for Weight Variation Control Introduction: In the pharmaceutical manufacturing industry, the production of tablets requires meticulous attention to detail to ensure consistent quality and efficacy. One critical aspect of tablet production is maintaining precise weight variation control, which directly impacts dosage…

Solid Dosage form, Tablets

Addressing Layer Delamination Issues in Multi-Layer Tablets During Equipment Validation

May 21, 2025 Admin

Addressing Layer Delamination Issues in Multi-Layer Tablets During Equipment Validation Addressing Layer Delamination Issues in Multi-Layer Tablets During Equipment Validation Introduction: In the pharmaceutical industry, multi-layer tablets are gaining prominence due to their ability to deliver multiple drugs or release profiles in a single dose. However, as beneficial as these tablets are, they come with…

Solid Dosage form, Tablets

Troubleshooting Brittleness in Coated Tablets During Validation Testing

May 21, 2025 Admin

Troubleshooting Brittleness in Coated Tablets During Validation Testing Troubleshooting Brittleness in Coated Tablets During Validation Testing Introduction: In the pharmaceutical industry, tablets are a common and vital dosage form. They offer precise dosing, ease of administration, and stability. However, the process of coating tablets, which enhances their appearance, taste, and stability, can introduce challenges. One…

Solid Dosage form, Tablets

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing

May 19, 2025 Admin

Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Resolving Layer Delamination in Multi-Layer Tablets Under Stress Testing Introduction: In the pharmaceutical industry, multi-layer tablets have become a sophisticated option for delivering multiple active pharmaceutical ingredients (APIs) with distinct release profiles. These tablets offer numerous advantages, including improved patient compliance and efficient dosing schedules. However,…

Solid Dosage form, Tablets

Addressing Non-Compliance in QA Tests for Multi-Layer Tablets

May 16, 2025 Admin

Addressing Non-Compliance in QA Tests for Multi-Layer Tablets Addressing Non-Compliance in QA Tests for Multi-Layer Tablets Introduction: In the pharmaceutical industry, multi-layer tablets have emerged as a preferred solid dosage form due to their ability to deliver multiple active pharmaceutical ingredients (APIs) in a single dose and to provide controlled release of medications. However, ensuring…

Solid Dosage form, Tablets

Investigating API Potency Retention in Immediate Release Tablets Over Time

May 11, 2025 Admin

Investigating API Potency Retention in Immediate Release Tablets Over Time Investigating API Potency Retention in Immediate Release Tablets Over Time Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of medicinal products is paramount. One critical aspect of this is the potency retention of the Active Pharmaceutical Ingredient (API) in immediate release tablets over…

Solid Dosage form, Tablets

Ensuring Proper Coding and Serialization in High-Speed Packaging Lines

May 6, 2025 Admin

Ensuring Proper Coding and Serialization in High-Speed Packaging Lines Ensuring Proper Coding and Serialization in High-Speed Packaging Lines Introduction: In the pharmaceutical industry, ensuring the integrity and traceability of products is paramount. With increasing regulatory requirements and the demand for transparency, coding and serialization in high-speed packaging lines have become essential for compliance and operational…

Solid Dosage form, Tablets

Ensuring Robustness in QA Monitoring for Immediate Release Tablets

May 5, 2025 Admin

Ensuring Robustness in QA Monitoring for Immediate Release Tablets Ensuring Robustness in QA Monitoring for Immediate Release Tablets Introduction: Quality Assurance (QA) in the pharmaceutical industry is a critical component that ensures the safety, efficacy, and quality of medicinal products. For immediate release tablets, which are designed to disintegrate and release their active pharmaceutical ingredients…

Solid Dosage form, Tablets

Managing Documentation Errors During QA Audits for Coated Tablets

May 5, 2025 Admin

Managing Documentation Errors During QA Audits for Coated Tablets Managing Documentation Errors During QA Audits for Coated Tablets Introduction: In the pharmaceutical industry, maintaining rigorous quality assurance (QA) standards is critical, particularly during the production of coated tablets. These solid dosage forms are widely used, and their efficacy and safety hinge on meticulous manufacturing processes…

Solid Dosage form, Tablets