Tag: pharmaceutical quality

Resolving Failures in Stability Testing Due to Packaging Interaction

March 3, 2025 Admin

Resolving Failures in Stability Testing Due to Packaging Interaction Resolving Failures in Stability Testing Due to Packaging Interaction Introduction: In the pharmaceutical industry, stability testing is crucial to ensure that a drug product maintains its intended quality, safety, and efficacy throughout its shelf life. Stability testing evaluates how environmental factors such as temperature, humidity, and…

Solid Dosage form, Tablets

Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions

March 3, 2025 Admin

Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Introduction: In the pharmaceutical industry, ensuring the consistency and quality of tablets is paramount. One of the critical quality attributes is tablet weight, which can be significantly affected by environmental conditions, particularly humidity. Weight variations…

Solid Dosage form, Tablets

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets

March 3, 2025 Admin

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Introduction: In the pharmaceutical industry, maintaining product integrity and patient safety is paramount. One of the significant challenges faced by manufacturers is the risk of cross-contamination, especially when utilizing shared utility lines for coated tablets….

Solid Dosage form, Tablets

Addressing Coating Layer Delamination During Quality Testing

March 3, 2025 Admin

Addressing Coating Layer Delamination During Quality Testing Addressing Coating Layer Delamination During Quality Testing Introduction: Coating layer delamination in tablets is a critical issue in the pharmaceutical industry, impacting both product efficacy and patient safety. The coating on a tablet not only serves an aesthetic function but also plays a crucial role in controlling the…

Solid Dosage form, Tablets

Managing Failures in Batch Sampling for Quality Assurance

March 2, 2025 Admin

Managing Failures in Batch Sampling for Quality Assurance Managing Failures in Batch Sampling for Quality Assurance Introduction: In the pharmaceutical industry, ensuring the quality of a product is paramount. Batch sampling plays a critical role in this process, providing a snapshot that represents the entire production batch. However, managing failures in batch sampling is crucial…

Solid Dosage form, Tablets

Managing Punch Adhesion Issues in Tablet Pressing Operations

March 2, 2025 Admin

Managing Punch Adhesion Issues in Tablet Pressing Operations Managing Punch Adhesion Issues in Tablet Pressing Operations Introduction: The process of tablet pressing is a critical stage in the production of solid dosage forms. One of the common issues faced during this process is punch adhesion, which can significantly affect the quality and consistency of the…

Solid Dosage form, Tablets

Managing Over-Lubrication in Blending Processes for Compression

March 2, 2025 Admin

Managing Over-Lubrication in Blending Processes for Compression Managing Over-Lubrication in Blending Processes for Compression Introduction: In the realm of pharmaceutical manufacturing, ensuring the quality and efficacy of solid dosage forms like tablets is paramount. The blending process, a critical step in tablet production, often involves the use of lubricants to improve the flow of powder…

Solid Dosage form, Tablets

High rejection rates due to uneven capsule drying.

March 2, 2025 Admin

High rejection rates due to uneven capsule drying. High Rejection Rates Due to Uneven Capsule Drying Introduction: The pharmaceutical industry constantly strives to enhance the quality and efficiency of its manufacturing processes. Among the myriad of challenges faced, the production of capsules, both hard and soft gelatin, stands out due to its complexity. One significant…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Common Causes of Cracking in Film Coatings During Quality Checks

March 1, 2025 Admin

Common Causes of Cracking in Film Coatings During Quality Checks Common Causes of Cracking in Film Coatings During Quality Checks Introduction: In pharmaceutical manufacturing, film coatings play a crucial role in ensuring tablet stability, controlling drug release, and enhancing the aesthetic appeal of the final product. However, one of the most common and challenging quality…

Solid Dosage form, Tablets

Difficulty in maintaining proper temperature control during heat sealing.

March 1, 2025 Admin

Difficulty in maintaining proper temperature control during heat sealing. Difficulty in Maintaining Proper Temperature Control During Heat Sealing Introduction: In the pharmaceutical industry, the integrity and quality of solid oral dosage forms are paramount. Capsules, both hard and soft gelatin, are prevalent due to their ability to encapsulate a wide range of active ingredients securely….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms