Tag: pharmaceutical quality control

Problems with ensuring consistent gelatin plasticizer levels over storage periods.

April 10, 2025 Admin

Problems with ensuring consistent gelatin plasticizer levels over storage periods. Problems with ensuring consistent gelatin plasticizer levels over storage periods. Introduction: Gelatin capsules, both hard and soft, are a cornerstone of pharmaceutical dosage forms due to their ease of ingestion and ability to encapsulate a wide variety of substances. A critical component in the manufacturing…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting microscopic cracks in gelatin shells.

April 8, 2025 Admin

Problems with detecting microscopic cracks in gelatin shells. Problems with Detecting Microscopic Cracks in Gelatin Shells Introduction: Gelatin capsules, both hard and soft, are integral to the pharmaceutical industry due to their effectiveness in encapsulating drugs and providing controlled release. However, ensuring the integrity of these capsules is critical, as even microscopic cracks in the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring capsule weight variation.

April 8, 2025 Admin

Poor reproducibility in monitoring capsule weight variation. Poor reproducibility in monitoring capsule weight variation. Introduction: Capsules, as solid oral dosage forms, play a critical role in the pharmaceutical industry due to their ease of administration, stability, and ability to encapsulate a variety of substances. However, ensuring consistent weight and content uniformity remains a significant challenge,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with achieving consistent shell thickness for multi-particulate capsules.

April 8, 2025 Admin

Problems with achieving consistent shell thickness for multi-particulate capsules. Problems with achieving consistent shell thickness for multi-particulate capsules. Introduction: In the pharmaceutical industry, the production of multi-particulate capsules has become increasingly significant due to their advantages in controlled drug release and patient compliance. However, achieving consistent shell thickness in these capsules is crucial for ensuring…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule transparency changes over time.

April 8, 2025 Admin

Inadequate systems for monitoring capsule transparency changes over time. Inadequate systems for monitoring capsule transparency changes over time. Introduction: In the realm of pharmaceuticals, maintaining the quality and integrity of solid oral dosage forms such as capsules is paramount. Capsules, both hard and soft gelatin, are popular due to their ease of administration and ability…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for detecting foreign particles in capsule packs.

April 7, 2025 Admin

Inadequate systems for detecting foreign particles in capsule packs. Inadequate systems for detecting foreign particles in capsule packs. Introduction: In the pharmaceutical industry, ensuring the purity and safety of solid oral dosage forms such as capsules is paramount. As capsules are a popular dosage form due to their convenience and effectiveness, maintaining their quality is…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring uniform capsule arrangement in multi-dose packs.

April 7, 2025 Admin

Difficulty in ensuring uniform capsule arrangement in multi-dose packs. Difficulty in ensuring uniform capsule arrangement in multi-dose packs. Introduction: In the pharmaceutical industry, the uniform arrangement of capsules in multi-dose packs is critical for ensuring dosage accuracy, patient safety, and compliance with regulatory standards. With the increasing complexity of drug formulations and the demand for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule filling processes for powders with variable particle size.

April 7, 2025 Admin

Difficulty in validating capsule filling processes for powders with variable particle size. Difficulty in Validating Capsule Filling Processes for Powders with Variable Particle Size Introduction: In the pharmaceutical industry, capsules are one of the most common forms of solid oral dosage. They offer numerous advantages, including ease of swallowing, better taste masking, and precise dosage….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with validating sterilization processes for gelatin solutions.

April 7, 2025 Admin

Problems with validating sterilization processes for gelatin solutions. Problems with validating sterilization processes for gelatin solutions. Introduction: Sterilization is a critical process in the pharmaceutical industry, especially for solid oral dosage forms like capsules. Gelatin solutions, used in both hard and soft gelatin capsules, require meticulous sterilization to ensure product safety and efficacy. However, validating…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Preventing Color Degradation in Sugar-Coated Tablets During UV Printing

April 7, 2025 Admin

Preventing Color Degradation in Sugar-Coated Tablets During UV Printing Preventing Color Degradation in Sugar-Coated Tablets During UV Printing Introduction: The pharmaceutical industry is constantly evolving, with technological advancements enhancing the quality and appearance of drug products. Among these advancements, UV printing on sugar-coated tablets offers a precise and efficient method for imprinting essential information. However,…

Solid Dosage form, Tablets

Poor reproducibility in fill material viscosity measurements during production.

April 6, 2025 Admin

Poor reproducibility in fill material viscosity measurements during production. Poor reproducibility in fill material viscosity measurements during production. Introduction: In the pharmaceutical industry, the production of capsules, both hard and soft gelatin, is a critical process that demands precision and consistency. One of the essential parameters in this process is the viscosity of the fill…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate validation of packaging line calibration processes.

April 6, 2025 Admin

Inadequate validation of packaging line calibration processes. Inadequate Validation of Packaging Line Calibration Processes Introduction: In the pharmaceutical industry, the packaging line serves as a critical component in ensuring that products reach consumers safely and effectively. However, inadequate validation of packaging line calibration processes can lead to significant issues, including compromised product integrity, regulatory non-compliance,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms