Tag: pharmaceutical quality control

Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets

June 2, 2025 Admin

Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets Troubleshooting Non-Adherence of Coating Layers in Multi-Layer Tablets Introduction: In the pharmaceutical industry, multi-layer tablets are gaining prominence due to their ability to deliver multiple drugs or achieve controlled release profiles. However, these complex formulations often face challenges, particularly with the adherence of coating layers. Ensuring that…

Solid Dosage form, Tablets

Preventing Color Fading in Sugar-Coated Tablets During Packaging

June 1, 2025 Admin

Preventing Color Fading in Sugar-Coated Tablets During Packaging Preventing Color Fading in Sugar-Coated Tablets During Packaging Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, providing an effective way to mask the taste of medication while enhancing its aesthetic appeal. However, maintaining the vibrant color of these tablets during packaging and storage is…

Solid Dosage form, Tablets

Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets

May 31, 2025 Admin

Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets Managing Calibration Failures in Dissolution Testing Equipment for Coated Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, especially for coated tablets. It ensures that the drug releases its active ingredients at the intended rate and extent. However, calibration failures…

Solid Dosage form, Tablets

Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation

May 29, 2025 Admin

Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation Ensuring Accuracy in Compression Force Sensors During Tablet Press Validation Introduction: In the pharmaceutical industry, precision in tablet manufacturing is paramount. Ensuring the accuracy of compression force sensors during tablet press validation is critical for maintaining the quality and uniformity of tablets. These sensors play…

Solid Dosage form, Tablets

Troubleshooting Failures in Rinse Sampling for Fluid Bed Dryers During Validation

May 28, 2025 Admin

Troubleshooting Failures in Rinse Sampling for Fluid Bed Dryers During Validation Troubleshooting Failures in Rinse Sampling for Fluid Bed Dryers During Validation Introduction: Rinse sampling is a critical step in the validation of fluid bed dryers within pharmaceutical manufacturing. Ensuring that no residues of active pharmaceutical ingredients (APIs) or cleaning agents remain is essential for…

Solid Dosage form, Tablets

Troubleshooting Label Placement Accuracy on Tablet Bottles

May 28, 2025 Admin

Troubleshooting Label Placement Accuracy on Tablet Bottles Troubleshooting Label Placement Accuracy on Tablet Bottles Introduction: In the pharmaceutical industry, the accurate placement of labels on tablet bottles is crucial for ensuring product compliance, safety, and traceability. Labels provide essential information such as dosage instructions, expiration dates, and batch numbers. Any inaccuracies in label placement can…

Solid Dosage form, Tablets

Ensuring Consistent Release Profiles in Multi-API Tablets Over Time

May 27, 2025 Admin

Ensuring Consistent Release Profiles in Multi-API Tablets Over Time Ensuring Consistent Release Profiles in Multi-API Tablets Over Time Introduction: In the pharmaceutical industry, the formulation and manufacturing of multi-API (Active Pharmaceutical Ingredient) tablets present a complex challenge. Ensuring consistent drug release profiles over time is crucial for therapeutic efficacy and patient safety. A consistent release…

Solid Dosage form, Tablets

Addressing Failures in Weight Variation Control During Compression Equipment Validation

May 26, 2025 Admin

Addressing Failures in Weight Variation Control During Compression Equipment Validation Addressing Failures in Weight Variation Control During Compression Equipment Validation Introduction: In the pharmaceutical industry, ensuring the consistency and quality of products is paramount, especially when it comes to solid dosage forms such as tablets. One critical aspect of tablet manufacturing is weight variation control…

Solid Dosage form, Tablets

Addressing Punch Wear Issues During Tablet Press Validation

May 25, 2025 Admin

Addressing Punch Wear Issues During Tablet Press Validation Addressing Punch Wear Issues During Tablet Press Validation Introduction: In the pharmaceutical manufacturing sector, ensuring the integrity and quality of tablet products is paramount. One critical aspect of this process is the validation of tablet presses, where punch wear can significantly impact product quality and efficiency. Punches,…

Solid Dosage form, Tablets

Root Cause Analysis of Weight Variation in Tablets During Stability Storage

May 24, 2025 Admin

Root Cause Analysis of Weight Variation in Tablets During Stability Storage Root Cause Analysis of Weight Variation in Tablets During Stability Storage Introduction: In the pharmaceutical industry, tablets remain one of the most common solid dosage forms, prized for their convenience, stability, and precise dosing. However, a critical aspect of tablet production and storage is…

Solid Dosage form, Tablets

Ensuring Robustness in Disintegration Time During Validation Testing

May 24, 2025 Admin

Ensuring Robustness in Disintegration Time During Validation Testing Ensuring Robustness in Disintegration Time During Validation Testing Introduction: In the pharmaceutical industry, the disintegration time of tablets is a critical quality attribute that directly impacts drug release and bioavailability. Ensuring robustness in disintegration time during validation testing is essential to maintain consistency in therapeutic efficacy and…

Solid Dosage form, Tablets

Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets

May 23, 2025 Admin

Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets Introduction: In the pharmaceutical industry, ensuring product safety and efficacy is paramount, and one critical aspect of this is managing cross-contamination risks. This is especially crucial in the production of extended-release tablets, where…

Solid Dosage form, Tablets