Tag: Pharmaceutical process troubleshooting]

Troubleshooting Powder Segregation Issues During Validation of Compression Lines

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Troubleshooting Powder Segregation Issues During Validation of Compression Lines Troubleshooting Powder Segregation Issues During Validation of Compression Lines Introduction: In the realm of pharmaceutical manufacturing, maintaining the uniformity and consistency of solid dosage forms, such as tablets, is crucial. One of the common challenges faced during the validation of compression lines is powder segregation. This…

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Solid Dosage form, Tablets

Troubleshooting Brittleness in High-Dose Tablets During Compression Validation

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Troubleshooting Brittleness in High-Dose Tablets During Compression Validation Troubleshooting Brittleness in High-Dose Tablets During Compression Validation Introduction: In the pharmaceutical industry, tablet formulation and manufacturing represent critical processes that significantly impact the quality, efficacy, and safety of the final product. High-dose tablets are particularly challenging to develop due to the increased risks of brittleness, which…

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Solid Dosage form, Tablets