Tag: Pharmaceutical process control

Managing Over-Spray in Sugar-Coating Processes During Validation Runs

May 6, 2025 Admin

Managing Over-Spray in Sugar-Coating Processes During Validation Runs Managing Over-Spray in Sugar-Coating Processes During Validation Runs Introduction: In the pharmaceutical industry, sugar-coating is a critical process for tablet production. It enhances the aesthetic appeal, masks unpleasant tastes, and provides a protective layer to the active pharmaceutical ingredients (APIs). However, managing over-spray during sugar-coating can present…

Solid Dosage form, Tablets

Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment

May 5, 2025 Admin

Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment Introduction: In the pharmaceutical industry, ensuring the safety and efficacy of drug products is paramount. With the increasing demand for diverse medications, many manufacturers utilize shared equipment for tablet production to optimize resources. However, shared equipment can pose significant…

Solid Dosage form, Tablets

Problems with ensuring consistent compressed air quality for capsule production.

April 19, 2025 Admin

Problems with ensuring consistent compressed air quality for capsule production. Problems with ensuring consistent compressed air quality for capsule production Introduction: In the pharmaceutical industry, the production of capsules, both hard and soft gelatin, requires strict adherence to quality standards, especially concerning the compressed air systems used in manufacturing processes. Compressed air is a critical…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring gelatin solution temperature during preparation.

April 18, 2025 Admin

Difficulty in monitoring gelatin solution temperature during preparation. Difficulty in Monitoring Gelatin Solution Temperature During Preparation Introduction: In the pharmaceutical industry, the preparation of gelatin solutions is a critical step in the manufacturing of both hard and soft gelatin capsules. Maintaining the appropriate temperature of the gelatin solution is crucial for ensuring the quality and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Detecting Agglomeration in Fluid Bed Granules During Drying

March 20, 2025 Admin

Detecting Agglomeration in Fluid Bed Granules During Drying Detecting Agglomeration in Fluid Bed Granules During Drying Introduction: Fluid bed granulation is a pivotal process in the pharmaceutical industry, integral to the production of tablets. It involves the transformation of fine powders into larger, free-flowing granules by fluidizing them in a bed and binding with a…

Solid Dosage form, Tablets

Validating Process Controls for High-Speed Granulation Equipment

March 16, 2025 Admin

Validating Process Controls for High-Speed Granulation Equipment Validating Process Controls for High-Speed Granulation Equipment Introduction: In the pharmaceutical industry, granulation is a critical process step in the production of solid dosage forms like tablets. High-speed granulation equipment is favored for its efficiency and capability to produce uniform granules, essential for consistent tablet quality. However, ensuring…

Solid Dosage form, Tablets

Managing Excessive Binder Use in Wet Granulation Processes

March 15, 2025 Admin

Managing Excessive Binder Use in Wet Granulation Processes Managing Excessive Binder Use in Wet Granulation Processes Introduction: In the pharmaceutical industry, wet granulation is a crucial process used to improve the flowability and compressibility of powder blends, ultimately ensuring the production of high-quality tablets. Binders play an essential role in wet granulation, providing the necessary…

Solid Dosage form, Tablets

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time

March 5, 2025 Admin

Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Resolving Non-Uniform API Distribution in Extended Release Tablets Over Time Introduction: The pharmaceutical industry is constantly evolving, with a significant focus on developing efficient drug delivery systems. Extended release tablets are a crucial component of this landscape, designed to release active pharmaceutical ingredients (APIs) over…

Solid Dosage form, Tablets