Tag: Pharmaceutical Industry

Difficulty in ensuring compliance with capsule-specific pharmacopeial standards.

April 24, 2025 Admin

Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Difficulty in ensuring compliance with capsule-specific pharmacopeial standards. Introduction: In the pharmaceutical industry, ensuring compliance with pharmacopeial standards is crucial for the safety and efficacy of drug products. Capsules, both hard and soft gelatin varieties, are a popular dosage form due to their convenience and ability to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating the stability of multi-particulate capsules.

April 23, 2025 Admin

Difficulty in evaluating the stability of multi-particulate capsules. Difficulty in evaluating the stability of multi-particulate capsules Introduction: In the pharmaceutical industry, ensuring the stability of drug products is crucial for maintaining their efficacy, safety, and quality over their shelf life. Multi-particulate capsules, which contain numerous small, discrete particles within a single dosage form, offer several…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing

April 21, 2025 Admin

Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Resolving Disintegration Failures in Sugar-Coated Tablets During Stability Testing Introduction: Sugar-coated tablets are a popular dosage form in the pharmaceutical industry, valued for their aesthetic appeal and ability to mask unpleasant tastes. However, these advantages can be overshadowed by challenges encountered during stability testing, particularly disintegration…

Solid Dosage form, Tablets

Inadequate systems for validating capsule hardness testing equipment.

April 21, 2025 Admin

Inadequate systems for validating capsule hardness testing equipment. Inadequate systems for validating capsule hardness testing equipment. Introduction: The pharmaceutical industry demands rigorous quality control measures to ensure the safety and efficacy of its products. Among these measures, validating equipment used for testing the hardness of capsules is crucial. Capsule hardness is an essential parameter that…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in assessing the stability of capsules containing low-dose APIs.

April 21, 2025 Admin

Difficulty in assessing the stability of capsules containing low-dose APIs. Difficulty in assessing the stability of capsules containing low-dose APIs. Introduction: In the pharmaceutical industry, ensuring the stability of drug products is paramount, particularly when dealing with capsules containing low-dose Active Pharmaceutical Ingredients (APIs). Stability refers to the ability of a drug product to maintain…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving consistent lubrication in encapsulation equipment.

April 20, 2025 Admin

Difficulty in achieving consistent lubrication in encapsulation equipment. Difficulty in achieving consistent lubrication in encapsulation equipment. Introduction: The encapsulation of pharmaceuticals, particularly in solid oral dosage forms like capsules, is a critical step in drug production. Achieving consistent lubrication in encapsulation equipment is pivotal for ensuring the smooth operation of machinery, maintaining product quality, and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor standardization of in-process quality control procedures.

April 20, 2025 Admin

Poor standardization of in-process quality control procedures. Poor standardization of in-process quality control procedures. Introduction: In the pharmaceutical industry, maintaining the highest quality standards is paramount. This is especially true for solid oral dosage forms, such as hard and soft gelatin capsules, where the absence of rigorous in-process quality control (IPQC) can lead to significant…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule tamper-evident packaging systems.

April 20, 2025 Admin

Poor validation of capsule tamper-evident packaging systems. Poor validation of capsule tamper-evident packaging systems. Introduction: In the pharmaceutical industry, ensuring the integrity and safety of drug products is paramount. Capsule tamper-evident packaging systems are essential in safeguarding these products from tampering and contamination, which can have dire consequences for both patient safety and company reputation….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate control over changes in raw material suppliers.

April 19, 2025 Admin

Inadequate control over changes in raw material suppliers. Inadequate control over changes in raw material suppliers Introduction: In the pharmaceutical industry, maintaining consistent quality and efficacy of products is paramount. One critical aspect that can significantly impact these factors is the control over raw material suppliers. Changes in suppliers can lead to variations in product…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving uniform fill weight for low-dose capsules.

April 18, 2025 Admin

Difficulty in achieving uniform fill weight for low-dose capsules. Difficulty in achieving uniform fill weight for low-dose capsules. Introduction: The pharmaceutical industry is constantly striving to ensure that medications are produced with the utmost precision and accuracy. One of the critical aspects of pharmaceutical manufacturing is achieving uniform fill weight in low-dose capsules. Low-dose medications…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Non-Adherence to GMP Standards in QA Processes

April 18, 2025 Admin

Managing Non-Adherence to GMP Standards in QA Processes Managing Non-Adherence to GMP Standards in QA Processes Introduction: In the pharmaceutical industry, maintaining strict adherence to Good Manufacturing Practice (GMP) standards is critical to ensuring the safety, efficacy, and quality of drug products. GMP standards, established by regulatory bodies such as the US FDA, provide a…

Solid Dosage form, Tablets

Problems with ensuring consistent capsule shell thickness across validation batches.

April 17, 2025 Admin

Problems with ensuring consistent capsule shell thickness across validation batches. Problems with Ensuring Consistent Capsule Shell Thickness Across Validation Batches Introduction: In the pharmaceutical industry, maintaining consistent capsule shell thickness across validation batches is critical for ensuring product quality and efficacy. The capsule shell not only protects the integrity of the encapsulated medication but also…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms