Tag: pharmaceutical formulations

Difficulty in validating capsule sealing for high-viscosity formulations.

April 23, 2025 Admin

Difficulty in validating capsule sealing for high-viscosity formulations. Difficulty in Validating Capsule Sealing for High-Viscosity Formulations Introduction: In the pharmaceutical industry, the development and manufacturing of solid oral dosage forms, specifically capsules, play a crucial role in delivering medications effectively to patients. Capsules, particularly those filled with high-viscosity formulations, present unique challenges in sealing validation….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving uniform fill weight for low-dose capsules.

April 18, 2025 Admin

Difficulty in achieving uniform fill weight for low-dose capsules. Difficulty in achieving uniform fill weight for low-dose capsules. Introduction: The pharmaceutical industry is constantly striving to ensure that medications are produced with the utmost precision and accuracy. One of the critical aspects of pharmaceutical manufacturing is achieving uniform fill weight in low-dose capsules. Low-dose medications…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving reproducibility in capsule shell thickness measurements.

April 13, 2025 Admin

Difficulty in achieving reproducibility in capsule shell thickness measurements. Difficulty in Achieving Reproducibility in Capsule Shell Thickness Measurements Introduction: In the pharmaceutical industry, ensuring the consistency and quality of solid oral dosage forms such as capsules is imperative. Capsule shell thickness is a critical quality attribute that affects the integrity, dissolution, and overall performance of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing

March 22, 2025 Admin

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Introduction: In the pharmaceutical industry, enteric-coated tablets play a crucial role in ensuring that active pharmaceutical ingredients (APIs) are delivered to the intestine, bypassing the acidic environment of the stomach. This not only protects the drug from…

Solid Dosage form, Tablets

Managing Failures in Residual Solvent Control for Purified Water Systems

March 11, 2025 Admin

Managing Failures in Residual Solvent Control for Purified Water Systems Managing Failures in Residual Solvent Control for Purified Water Systems Introduction: The pharmaceutical industry heavily relies on purified water systems to ensure the quality and efficacy of its products. As such, managing residual solvents in these systems is critical for maintaining product safety and compliance…

Solid Dosage form, Tablets

Managing Failure in Moisture Content Tests for Hygroscopic Tablets

March 10, 2025 Admin

Managing Failure in Moisture Content Tests for Hygroscopic Tablets Managing Failure in Moisture Content Tests for Hygroscopic Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of medicinal products is paramount. Hygroscopic tablets, which are prone to absorbing moisture from the environment, present unique challenges in this regard. Moisture content tests are critical…

Solid Dosage form, Tablets

Problems with detecting improper sealing in high-viscosity formulations.

March 4, 2025 Admin

Problems with detecting improper sealing in high-viscosity formulations. Problems with Detecting Improper Sealing in High-Viscosity Formulations Introduction: In pharmaceutical manufacturing, ensuring the integrity of solid oral dosage forms is paramount. Capsules, both hard and soft gelatin, are popular due to their versatility and patient compliance. However, when dealing with high-viscosity formulations, improper sealing poses significant…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Failures in Stability Testing Due to Packaging Interaction

March 3, 2025 Admin

Resolving Failures in Stability Testing Due to Packaging Interaction Resolving Failures in Stability Testing Due to Packaging Interaction Introduction: In the pharmaceutical industry, stability testing is crucial to ensure that a drug product maintains its intended quality, safety, and efficacy throughout its shelf life. Stability testing evaluates how environmental factors such as temperature, humidity, and…

Solid Dosage form, Tablets