Tag: pharmaceutical defects

Difficulty in detecting microscopic defects in capsule shells.

April 9, 2025 Admin

Difficulty in detecting microscopic defects in capsule shells. Difficulty in Detecting Microscopic Defects in Capsule Shells Introduction: Capsules are one of the most popular solid oral dosage forms in the pharmaceutical industry, offering a convenient and effective means of drug delivery. However, maintaining the integrity and quality of capsule shells is crucial, as defects can…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting microscopic cracks in gelatin shells.

April 8, 2025 Admin

Problems with detecting microscopic cracks in gelatin shells. Problems with Detecting Microscopic Cracks in Gelatin Shells Introduction: Gelatin capsules, both hard and soft, are integral to the pharmaceutical industry due to their effectiveness in encapsulating drugs and providing controlled release. However, ensuring the integrity of these capsules is critical, as even microscopic cracks in the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for detecting air bubbles in soft gelatin capsules.

March 29, 2025 Admin

Inadequate systems for detecting air bubbles in soft gelatin capsules. Inadequate Systems for Detecting Air Bubbles in Soft Gelatin Capsules Introduction: Soft gelatin capsules are a popular dosage form in the pharmaceutical industry due to their ease of swallowing and ability to encapsulate a wide range of active ingredients. However, ensuring the quality and integrity…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Real-Time Detection of Defects in Coated Tablet Layers

March 19, 2025 Admin

Real-Time Detection of Defects in Coated Tablet Layers Real-Time Detection of Defects in Coated Tablet Layers Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of tablets is of paramount importance. Coated tablets are widely used not only for aesthetic purposes but also to enhance stability, control release profiles, and mask unpleasant tastes. However,…

Solid Dosage form, Tablets

Inadequate systems for monitoring capsule defect trends over time.

March 16, 2025 Admin

Inadequate systems for monitoring capsule defect trends over time. Inadequate systems for monitoring capsule defect trends over time. Introduction: The pharmaceutical industry is under constant pressure to maintain high standards of quality and safety, particularly when it comes to solid oral dosage forms such as capsules. Capsules, which can be either hard or soft gelatin,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Layer Cracks in Bilayer Tablets During Validation

March 15, 2025 Admin

Troubleshooting Layer Cracks in Bilayer Tablets During Validation Troubleshooting Layer Cracks in Bilayer Tablets During Validation Introduction: Bilayer tablets have gained significant traction in the pharmaceutical industry due to their ability to deliver multiple drugs with distinct release profiles in a single dosage form. However, during the manufacturing process, these tablets can present unique challenges,…

Solid Dosage form, Tablets

Difficulty in detecting shell cracks during high-speed manufacturing.

March 9, 2025 Admin

Difficulty in detecting shell cracks during high-speed manufacturing. Difficulty in detecting shell cracks during high-speed manufacturing. Introduction: Capsules, both hard and soft gelatin, are among the most popular solid oral dosage forms in the pharmaceutical industry. Their wide acceptance is due to their versatility in delivering a variety of active pharmaceutical ingredients (APIs). However, the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms