Tag: pharmaceutical best practices

Problems with validating capsule printing for transparent capsules.

March 4, 2025 Admin

Problems with validating capsule printing for transparent capsules. Problems with validating capsule printing for transparent capsules. Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form due to their versatility, ease of administration, and ability to encapsulate a variety of drug formulations. Among the different types of capsules, transparent capsules have gained…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Failures in Steam Quality Validation for Enteric-Coated Tablet Equipment

March 4, 2025 Admin

Managing Failures in Steam Quality Validation for Enteric-Coated Tablet Equipment Managing Failures in Steam Quality Validation for Enteric-Coated Tablet Equipment Introduction: In the pharmaceutical industry, ensuring the sterility and quality of equipment used in the manufacturing process is critical, especially for enteric-coated tablets. Steam quality validation is a vital component of this quality assurance process….

Solid Dosage form, Tablets

Managing Failures in Weight Variation Testing for Sustained Release Tablets

March 4, 2025 Admin

Managing Failures in Weight Variation Testing for Sustained Release Tablets Managing Failures in Weight Variation Testing for Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the consistent quality of sustained release tablets is crucial, as they are designed to release medication over an extended period. Weight variation testing is a critical quality control measure…

Solid Dosage form, Tablets

Addressing Failures in Coating Thickness Tests for Multi-Layer Tablets

March 3, 2025 Admin

Addressing Failures in Coating Thickness Tests for Multi-Layer Tablets Addressing Failures in Coating Thickness Tests for Multi-Layer Tablets Introduction: In the pharmaceutical industry, ensuring the quality of multi-layer tablets is paramount. One critical aspect is the coating thickness, which directly impacts the tablet’s dissolution rate, stability, and overall efficacy. Coating failures can lead to significant…

Solid Dosage form, Tablets

Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions

March 3, 2025 Admin

Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Resolving Weight Variations in Tablets Stored in Variable Humidity Conditions Introduction: In the pharmaceutical industry, ensuring the consistency and quality of tablets is paramount. One of the critical quality attributes is tablet weight, which can be significantly affected by environmental conditions, particularly humidity. Weight variations…

Solid Dosage form, Tablets

Managing Non-Uniform API Distribution in Content Uniformity Tests

March 3, 2025 Admin

Managing Non-Uniform API Distribution in Content Uniformity Tests Managing Non-Uniform API Distribution in Content Uniformity Tests Introduction: The uniform distribution of the Active Pharmaceutical Ingredient (API) in solid dosage forms, such as tablets, is a critical quality attribute in pharmaceutical manufacturing. The reliability of therapeutic outcomes and patient safety hinges on the consistent delivery of…

Solid Dosage form, Tablets

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets

March 3, 2025 Admin

Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Addressing Cross-Contamination Risks in Shared Utility Lines for Coated Tablets Introduction: In the pharmaceutical industry, maintaining product integrity and patient safety is paramount. One of the significant challenges faced by manufacturers is the risk of cross-contamination, especially when utilizing shared utility lines for coated tablets….

Solid Dosage form, Tablets

Identifying Failures in Adhesion Tests for Film Coatings

March 3, 2025 Admin

Identifying Failures in Adhesion Tests for Film Coatings Identifying Failures in Adhesion Tests for Film Coatings Introduction: In the pharmaceutical industry, film coatings on tablets serve multiple critical functions, including masking unpleasant tastes, enhancing tablet stability, and controlling drug release. Ensuring the adhesion of these coatings is vital for maintaining product integrity and efficacy. Failures…

Solid Dosage form, Tablets

Validating Steam Distribution Systems for Multi-Product Tablet Manufacturing Facilities

March 3, 2025 Admin

Validating Steam Distribution Systems for Multi-Product Tablet Manufacturing Facilities Validating Steam Distribution Systems for Multi-Product Tablet Manufacturing Facilities Introduction: In the dynamic world of pharmaceutical manufacturing, ensuring the integrity and efficacy of the production process is paramount. Steam distribution systems play a critical role in tablet manufacturing, especially in multi-product facilities where the complexity of…

Solid Dosage form, Tablets

Difficulty in validating cleaning procedures for encapsulation molds exposed to dyes

March 3, 2025 Admin

Difficulty in validating cleaning procedures for encapsulation molds exposed to dyes Difficulty in validating cleaning procedures for encapsulation molds exposed to dyes Introduction: In the pharmaceutical industry, the production of capsules—both hard and soft gelatin—often involves the use of various dyes to achieve the desired aesthetic and functional properties. These dyes can pose significant challenges…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets

March 3, 2025 Admin

Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets Addressing Non-Uniform Coating Thickness in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a time-tested pharmaceutical dosage form, favored for their aesthetic appeal, masking of unpleasant tastes, and protection of the core tablet. Achieving a uniformly coated product is critical not only for consumer acceptance but also for ensuring consistent…

Solid Dosage form, Tablets

Preventing Powder Loss During Compression in High-Speed Machines

March 2, 2025 Admin

Preventing Powder Loss During Compression in High-Speed Machines Preventing Powder Loss During Compression in High-Speed Machines Introduction: The pharmaceutical industry is renowned for its stringent quality standards, especially in the manufacturing of solid dosage forms like tablets. One critical aspect of tablet production is the compression process, which often faces the challenge of powder loss….

Solid Dosage form, Tablets