Tag: pharmaceutical best practices

Managing Calibration Failures in Temperature Sensors for Purified Water Systems

March 13, 2025 Admin

Managing Calibration Failures in Temperature Sensors for Purified Water Systems Managing Calibration Failures in Temperature Sensors for Purified Water Systems Introduction: In the pharmaceutical industry, maintaining the integrity of purified water systems is crucial for ensuring product quality and safety. Temperature sensors play a vital role in these systems by monitoring and maintaining the required…

Solid Dosage form, Tablets

Difficulty in achieving uniform distribution of capsules within packs.

March 13, 2025 Admin

Difficulty in achieving uniform distribution of capsules within packs. Difficulty in Achieving Uniform Distribution of Capsules within Packs Introduction: The pharmaceutical industry is continually evolving, driven by the need to ensure product efficacy, safety, and consumer satisfaction. Solid oral dosage forms, particularly capsules, are a staple in the industry due to their ease of administration…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in validation data for semi-automated encapsulation systems.

March 13, 2025 Admin

Poor reproducibility in validation data for semi-automated encapsulation systems. Poor reproducibility in validation data for semi-automated encapsulation systems. Introduction: In the pharmaceutical industry, the precision and consistency of encapsulation systems, particularly semi-automated ones, are paramount. Encapsulation plays a vital role in drug delivery, ensuring each dose contains the correct amount of active pharmaceutical ingredient (API)….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Failures in Content Uniformity Tests for Immediate Release Tablets

March 13, 2025 Admin

Managing Failures in Content Uniformity Tests for Immediate Release Tablets Managing Failures in Content Uniformity Tests for Immediate Release Tablets Introduction: In the world of pharmaceutical manufacturing, ensuring that each tablet contains the precise amount of active ingredient is crucial for both efficacy and safety. This is particularly true for immediate-release tablets, where rapid onset…

Solid Dosage form, Tablets

Identifying Causes of Friability Failures in Sugar-Coated Tablets

March 12, 2025 Admin

Identifying Causes of Friability Failures in Sugar-Coated Tablets Identifying Causes of Friability Failures in Sugar-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the quality and integrity of solid dosage forms is of paramount importance. Tablets, especially sugar-coated ones, are widely used due to their ease of administration and patient compliance. However, the friability of these…

Solid Dosage form, Tablets

Problems with validating capsule weight variation for soft gelatin capsules.

March 12, 2025 Admin

Problems with validating capsule weight variation for soft gelatin capsules. Problems with validating capsule weight variation for soft gelatin capsules. Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms like soft gelatin capsules is crucial. These capsules are widely used due to their bioavailability and patient compliance. However, one…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Spray Pattern Issues in Sugar-Coating Processes

March 12, 2025 Admin

Troubleshooting Spray Pattern Issues in Sugar-Coating Processes Troubleshooting Spray Pattern Issues in Sugar-Coating Processes Introduction: Sugar-coating is a critical process in pharmaceutical tablet manufacturing, providing not only aesthetic appeal but also functional benefits like taste masking and moisture protection. However, achieving a uniform sugar coat is often fraught with challenges, particularly when it comes to…

Solid Dosage form, Tablets

Preventing Tablet Damage During Drop Testing of Blister Packs

March 12, 2025 Admin

Preventing Tablet Damage During Drop Testing of Blister Packs Preventing Tablet Damage During Drop Testing of Blister Packs Introduction: In the pharmaceutical industry, ensuring the integrity of solid dosage forms such as tablets is crucial to maintaining product efficacy and patient safety. Blister packs are a common packaging solution designed to protect tablets from environmental…

Solid Dosage form, Tablets

Managing Failures in Moisture Content Tests for Hygroscopic APIs

March 11, 2025 Admin

Managing Failures in Moisture Content Tests for Hygroscopic APIs Managing Failures in Moisture Content Tests for Hygroscopic APIs Introduction: In the pharmaceutical industry, Active Pharmaceutical Ingredients (APIs) form the backbone of drug manufacturing. Among these, hygroscopic APIs present unique challenges due to their inherent ability to absorb moisture from the environment. Accurate moisture content testing…

Solid Dosage form, Tablets

Lack of robust methods for real-time moisture content monitoring in capsules.

March 11, 2025 Admin

Lack of robust methods for real-time moisture content monitoring in capsules. Lack of robust methods for real-time moisture content monitoring in capsules. Introduction: Moisture content within pharmaceutical capsules is a critical quality attribute that can significantly affect the product’s efficacy, stability, and shelf life. Both hard and soft gelatin capsules are particularly susceptible to moisture…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Preventing Tablet Capping During High-Speed Compression

March 11, 2025 Admin

Preventing Tablet Capping During High-Speed Compression Preventing Tablet Capping During High-Speed Compression Introduction: The pharmaceutical industry is ever-evolving, with technological advancements pushing the boundaries of speed and efficiency in drug manufacturing. Tablets, as a prevalent solid dosage form, are at the forefront of this evolution. However, with high-speed compression, challenges such as tablet capping can…

Solid Dosage form, Tablets

Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets

March 11, 2025 Admin

Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets Addressing Spray Pattern Variability in Coating Machines for Sustained Release Tablets Introduction: The pharmaceutical industry continually strives to enhance the quality and efficacy of its products, with sustained release tablets playing a vital role in modern medicine. These tablets offer prolonged therapeutic effects, improving…

Solid Dosage form, Tablets