Tag: Pharma manufacturing

Addressing Misalignment of Leaflets in Carton Folding Machines

April 12, 2025 Admin

Addressing Misalignment of Leaflets in Carton Folding Machines Addressing Misalignment of Leaflets in Carton Folding Machines Introduction: In the pharmaceutical industry, ensuring precise leaflet placement in carton folding machines is critical for maintaining packaging integrity and compliance. The correct alignment of leaflets not only upholds the aesthetic quality but is also vital for meeting regulatory…

Solid Dosage form, Tablets

Inadequate systems for monitoring packaging line efficiency.

April 5, 2025 Admin

Inadequate systems for monitoring packaging line efficiency. Inadequate systems for monitoring packaging line efficiency. Introduction: In the pharmaceutical industry, ensuring the efficiency of packaging lines is crucial for maintaining product quality and meeting production demands. Packaging lines, especially in the context of solid oral dosage forms like capsules, can be complex and involve numerous variables….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in preventing capsule movement within blister cavities.

April 5, 2025 Admin

Difficulty in preventing capsule movement within blister cavities. Difficulty in Preventing Capsule Movement within Blister Cavities Introduction: In pharmaceutical packaging, blister packs have become the standard for protecting solid oral dosage forms, such as capsules. These packs offer numerous benefits, including protection from environmental factors, tamper evidence, and patient compliance. However, one persistent issue is…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Preventing Over-Drying of Granules During Fluid Bed Processing

April 1, 2025 Admin

Preventing Over-Drying of Granules During Fluid Bed Processing Preventing Over-Drying of Granules During Fluid Bed Processing Introduction: Fluid bed processing is a cornerstone of pharmaceutical manufacturing, especially in the production of solid dosage forms such as tablets. The process involves suspending particles in a flowing gas stream, typically air, which facilitates the drying of granules…

Solid Dosage form, Tablets

Managing Packing Material Variation for Consistency in Blister Packaging

March 21, 2025 Admin

Managing Packing Material Variation for Consistency in Blister Packaging Managing Packing Material Variation for Consistency in Blister Packaging Introduction: In the pharmaceutical industry, blister packaging serves as a critical component for ensuring the stability and protection of solid dosage forms like tablets. The packaging not only safeguards the medication but also ensures patient compliance and…

Solid Dosage form, Tablets

Challenges in validating gelatin mixing tanks for uniform temperature control.

March 14, 2025 Admin

Challenges in validating gelatin mixing tanks for uniform temperature control. Challenges in validating gelatin mixing tanks for uniform temperature control. Introduction: In the pharmaceutical industry, the production of capsules, particularly those made from gelatin, is a complex process that demands precision and consistency. Gelatin, a critical component in both hard and soft gelatin capsules, requires…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets

March 13, 2025 Admin

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Introduction: In the pharmaceutical industry, the coating of tablets plays a crucial role in the product’s performance and patient acceptability. High-speed coating of sugar-coated tablets is a sophisticated process that necessitates precise equipment validation to ensure consistent…

Solid Dosage form, Tablets

Addressing Overheating Issues in Heat-Sealing Equipment

March 11, 2025 Admin

Addressing Overheating Issues in Heat-Sealing Equipment Addressing Overheating Issues in Heat-Sealing Equipment Introduction: Heat-sealing equipment is pivotal in the pharmaceutical sector, particularly in the packaging of solid dosage forms like tablets. These machines ensure the integrity and safety of pharmaceutical products by creating airtight seals that protect against environmental factors. However, overheating can pose significant…

Solid Dosage form, Tablets

Difficulty in validating cleaning procedures for equipment exposed to hygroscopic powders.

March 8, 2025 Admin

Difficulty in validating cleaning procedures for equipment exposed to hygroscopic powders. Difficulty in validating cleaning procedures for equipment exposed to hygroscopic powders. Introduction: In the pharmaceutical industry, ensuring the cleanliness of manufacturing equipment is paramount to maintaining product quality and safety. This task becomes particularly challenging when dealing with hygroscopic powders, which are prone to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Ensuring Consistency in Clean Steam Quality for Fluid Bed Granulators

March 8, 2025 Admin

Ensuring Consistency in Clean Steam Quality for Fluid Bed Granulators Ensuring Consistency in Clean Steam Quality for Fluid Bed Granulators Introduction: In the pharmaceutical industry, the quality of clean steam used in fluid bed granulators is paramount. Clean steam is crucial for maintaining the integrity and efficacy of the final product, as it is directly…

Solid Dosage form, Tablets

Managing Static Electricity in Packaging Operations for Hygroscopic Tablets

March 5, 2025 Admin

Managing Static Electricity in Packaging Operations for Hygroscopic Tablets Managing Static Electricity in Packaging Operations for Hygroscopic Tablets Introduction: In the pharmaceutical industry, the packaging of hygroscopic tablets presents unique challenges, primarily due to their affinity for moisture. Static electricity can exacerbate these challenges by attracting particles and causing tablets to clump together, leading to…

Solid Dosage form, Tablets

Poor reproducibility in capsule sealing tests for blister packs.

March 4, 2025 Admin

Poor reproducibility in capsule sealing tests for blister packs. Poor reproducibility in capsule sealing tests for blister packs. Introduction: The pharmaceutical industry heavily relies on blister packaging to protect and deliver solid oral dosage forms like capsules. Ensuring the integrity of capsule seals in blister packs is crucial for maintaining the product’s efficacy, stability, and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms