Tag: Granulation

Addressing Over-Drying Issues in Granulation During Validation Runs

April 24, 2025 Admin

Addressing Over-Drying Issues in Granulation During Validation Runs Addressing Over-Drying Issues in Granulation During Validation Runs Introduction: In the pharmaceutical industry, granulation is a critical step in the production of solid dosage forms such as tablets. It involves the agglomeration of powder particles to form granules, which enhance the flowability and compressibility of the powder,…

Solid Dosage form, Tablets

Inadequate systems for detecting powder compaction issues during filling.

April 2, 2025 Admin

Inadequate systems for detecting powder compaction issues during filling. Inadequate systems for detecting powder compaction issues during filling. Introduction: In the pharmaceutical industry, the precision and reliability of capsule filling are paramount to ensure product efficacy and patient safety. Hard and soft gelatin capsules are popular dosage forms, offering versatility in delivering active pharmaceutical ingredients…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Powder Segregation During Blending for Immediate Release Tablets

March 25, 2025 Admin

Managing Powder Segregation During Blending for Immediate Release Tablets Managing Powder Segregation During Blending for Immediate Release Tablets Introduction: The pharmaceutical industry constantly strives to ensure the production of high-quality and effective medications. One of the crucial aspects of manufacturing immediate release tablets is the management of powder segregation during blending. Powder segregation can compromise…

Solid Dosage form, Tablets

Addressing Over-Lubrication in Powder Mixtures for Blending

March 21, 2025 Admin

Addressing Over-Lubrication in Powder Mixtures for Blending Addressing Over-Lubrication in Powder Mixtures for Blending Introduction: In the pharmaceutical industry, the formulation of solid dosage forms like tablets is a finely tuned process that requires precision and careful consideration of multiple variables. Among these, the use of lubricants in powder mixtures for blending is crucial to…

Solid Dosage form, Tablets

Controlling Agglomeration in Powder Blending for High-Speed Compression

March 21, 2025 Admin

Controlling Agglomeration in Powder Blending for High-Speed Compression Controlling Agglomeration in Powder Blending for High-Speed Compression Introduction: In the pharmaceutical industry, the process of powder blending is a critical step in the production of solid dosage forms, particularly tablets. High-speed compression demands a high level of powder homogeneity to ensure tablet consistency and efficacy. However,…

Solid Dosage form, Tablets

Preventing Powder Loss During Tablet Compression

March 18, 2025 Admin

Preventing Powder Loss During Tablet Compression Preventing Powder Loss During Tablet Compression Introduction: Tablet compression is a critical process in pharmaceutical manufacturing, responsible for converting powder into solid dosage forms like tablets. Ensuring efficiency during this process is vital for maintaining product quality, consistency, and cost-effectiveness. Powder loss during tablet compression can lead to significant…

Solid Dosage form, Tablets

Troubleshooting Powder Flow Issues in Tablet Press Feed Systems

March 18, 2025 Admin

Troubleshooting Powder Flow Issues in Tablet Press Feed Systems Troubleshooting Powder Flow Issues in Tablet Press Feed Systems Introduction: The efficiency of tablet manufacturing significantly hinges on the flawless flow of powder within tablet press feed systems. Proper flow ensures uniformity, consistency, and quality in the final product, which is crucial for both efficacy and…

Solid Dosage form, Tablets

Difficulty in maintaining uniform mixing of powder blends.

March 16, 2025 Admin

Difficulty in maintaining uniform mixing of powder blends. Difficulty in maintaining uniform mixing of powder blends. Introduction: In the pharmaceutical industry, achieving uniform mixing of powder blends is paramount for the production of effective and safe solid oral dosage forms, such as capsules and tablets. Uniformity in powder blends ensures consistent drug delivery, efficacy, and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Identifying Root Causes of Capping in Compression Stages

March 10, 2025 Admin

Identifying Root Causes of Capping in Compression Stages Identifying Root Causes of Capping in Compression Stages Introduction: In the pharmaceutical industry, the compression stage of tablet manufacturing is crucial. It is during this stage that granulated material is transformed into tablets of uniform size and dosage. However, this process is not without its challenges. One…

Solid Dosage form, Tablets

Controlling Powder Flow in Feed Frames for Film-Coated Tablets

March 10, 2025 Admin

Controlling Powder Flow in Feed Frames for Film-Coated Tablets Controlling Powder Flow in Feed Frames for Film-Coated Tablets Introduction: The pharmaceutical industry relies heavily on the production of solid dosage forms, with tablets being one of the most common. Ensuring consistent and reliable production of film-coated tablets requires precise control over several variables, one of…

Solid Dosage form, Tablets

Real-Time Adjustment of Granulation Parameters for Uniformity

March 9, 2025 Admin

Real-Time Adjustment of Granulation Parameters for Uniformity Real-Time Adjustment of Granulation Parameters for Uniformity Introduction: In the pharmaceutical industry, the uniformity of granulation is critical for ensuring the quality and efficacy of solid dosage forms, particularly tablets. Granulation is a pivotal step in the tablet manufacturing process, where powder particles are aggregated to form granules….

Solid Dosage form, Tablets

Challenges in Binder Addition During Granulation

March 9, 2025 Admin

Challenges in Binder Addition During Granulation Challenges in Binder Addition During Granulation Introduction: In the pharmaceutical industry, granulation is a crucial process in the production of solid dosage forms such as tablets. It involves the agglomeration of powder particles to form larger entities known as granules. One of the most critical components in the granulation…

Solid Dosage form, Tablets