Tag: [Gelatin cross-linking

Challenges in detecting cross-linking of gelatin in hard capsules.

April 17, 2025 Admin

Challenges in detecting cross-linking of gelatin in hard capsules. Challenges in detecting cross-linking of gelatin in hard capsules. Introduction: Gelatin capsules, especially hard gelatin capsules, are a cornerstone in the pharmaceutical industry, prized for their versatility and efficiency in delivering medications. However, one significant challenge that can impact their performance is gelatin cross-linking. This chemical…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in testing soft gelatin capsules with high oil content.

April 16, 2025 Admin

Challenges in testing soft gelatin capsules with high oil content. Challenges in testing soft gelatin capsules with high oil content Introduction: Soft gelatin capsules are a popular dosage form in the pharmaceutical industry, offering unique advantages such as improved bioavailability and patient compliance. However, when these capsules contain high oil content, they present significant challenges…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining consistent dissolution profiles over the product’s shelf life.

April 13, 2025 Admin

Problems with maintaining consistent dissolution profiles over the product’s shelf life. Problems with maintaining consistent dissolution profiles over the product’s shelf life. Introduction: The dissolution profile of a pharmaceutical product is a critical parameter that impacts its efficacy and safety. Consistency in dissolution profiles over the product’s shelf life ensures that the drug is released…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in gelatin cross-linking data under various storage conditions.

April 4, 2025 Admin

Poor reproducibility in gelatin cross-linking data under various storage conditions. Poor Reproducibility in Gelatin Cross-Linking Data Under Various Storage Conditions Introduction: In the pharmaceutical industry, the stability and integrity of solid oral dosage forms, particularly capsules, are paramount. Gelatin, a common excipient used in hard and soft capsules, undergoes a process known as cross-linking, which…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring gelatin cross-linking during validation.

March 3, 2025 Admin

Inadequate systems for monitoring gelatin cross-linking during validation. Inadequate systems for monitoring gelatin cross-linking during validation. Introduction: Gelatin capsules, both hard and soft gelatin, are widely used in the pharmaceutical industry due to their versatility and patient compliance benefits. However, one of the key challenges faced during the formulation and manufacturing of gelatin capsules is…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms