Equipment Troubleshooting – Page 35

Over-wetting observed during drying phase – inspection risk analysis

Mitigating Over-Wetting Issues in the Drying Phase: A Practical Guide Over-wetting observed during the drying phase of pharmaceutical manufacturing poses significant risks to product quality, compliance, and overall operational efficiency.…

Granule attrition issue during drying phase – process vs equipment root cause

Addressing Granule Attrition Issues During the Drying Phase: Equipment vs Process Root Causes During the pharmaceutical manufacturing process, granule attrition can pose significant quality risks, particularly during the drying phase.…

FBD drying inconsistency after scale-up – inspection risk analysis

Resolving Inconsistent FBD Drying Post-Scale-Up: An Inspection Readiness Approach In the pharmaceutical manufacturing sector, complications during scale-up processes can manifest as significant inconsistencies in fluid bed dryer (FBD) performance, particularly…

Over-wetting observed after scale-up – CAPA and control strategy gap

Addressing Over-Wetting in Granulation After Scale-Up: A Practical CAPA Framework In the pharmaceutical manufacturing realm, scaling up from lab to production can pose significant challenges, one of which is the…

Capsule fill weight variability during encapsulation – equipment vs material root cause

Addressing Capsule Fill Weight Variability During Encapsulation: Equipment and Material Root Cause Analysis Capsule fill weight variability during encapsulation is a significant issue that can compromise product quality and compliance,…

Segment wear issue during long campaigns – CAPA effectiveness gap

Addressing Segment Wear in Capsule Filling Machines During Extended Production Runs In pharmaceutical manufacturing, particularly in capsule filling processes, segment wear can lead to significant challenges, particularly during long production…

Powder leakage during encapsulation – CAPA effectiveness gap

Addressing Powder Leakage in Encapsulation: A Comprehensive CAPA Approach Powder leakage during encapsulation can significantly affect product quality, compliance, and operational efficiency in pharmaceutical manufacturing. This failure can lead to…

Capsule fill weight variability after maintenance – equipment vs material root cause

Investigating Capsule Fill Weight Variability Following Equipment Maintenance Capsule fill weight variability is a significant concern in pharmaceutical manufacturing, particularly following equipment maintenance. This problem can lead to non-conformance with…

Tag: Equipment Troubleshooting

Over-wetting observed during drying phase – inspection risk analysis

Granule attrition issue during drying phase – process vs equipment root cause

FBD drying inconsistency after scale-up – inspection risk analysis

Over-wetting observed after scale-up – CAPA and control strategy gap

Capsule fill weight variability during encapsulation – equipment vs material root cause

Segment wear issue during long campaigns – CAPA effectiveness gap

Powder leakage during encapsulation – CAPA effectiveness gap

Capsule fill weight variability after maintenance – equipment vs material root cause

Capsule orientation failure during long campaigns – regulatory inspection finding

Dosator malfunction during long campaigns – equipment vs material root cause

Improper capsule locking during inspection – regulatory inspection finding

Segment wear issue after format change – equipment vs material root cause