Tag: Equipment Maintenance

Difficulty in achieving consistent calibration of capsule weight variation equipment.

March 18, 2025 Admin

Difficulty in achieving consistent calibration of capsule weight variation equipment. Difficulty in achieving consistent calibration of capsule weight variation equipment. Introduction: In the pharmaceutical industry, ensuring the consistent weight of capsules is crucial for product efficacy and safety. Capsules, whether hard or soft gelatin, must meet stringent weight specifications to ensure uniformity in dosage and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Cleaning Validation Failures in Compression Machines for Multi-API Tablets

March 18, 2025 Admin

Troubleshooting Cleaning Validation Failures in Compression Machines for Multi-API Tablets Troubleshooting Cleaning Validation Failures in Compression Machines for Multi-API Tablets Introduction: In the pharmaceutical industry, ensuring the cleanliness of equipment is paramount, especially when manufacturing multi-active pharmaceutical ingredient (API) tablets. Cleaning validation is a critical process that confirms the effectiveness of cleaning procedures to prevent…

Solid Dosage form, Tablets

Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment

March 17, 2025 Admin

Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment Ensuring Adequacy of Compressed Air Pressure for Granulation Equipment Introduction: In the pharmaceutical manufacturing industry, ensuring the adequacy of compressed air pressure for granulation equipment is crucial for producing high-quality solid dosage forms. Granulation is a key process in tablet production, impacting the uniformity, compressibility, and…

Solid Dosage form, Tablets

Addressing Overheating Issues in HVAC Systems for High-Volume Tablet Production

March 17, 2025 Admin

Addressing Overheating Issues in HVAC Systems for High-Volume Tablet Production Addressing Overheating Issues in HVAC Systems for High-Volume Tablet Production Introduction: In the pharmaceutical industry, maintaining optimal environmental conditions is crucial for the manufacturing of solid dosage forms, particularly tablets. HVAC (Heating, Ventilation, and Air Conditioning) systems play a vital role in regulating temperature and…

Solid Dosage form, Tablets

Managing Calibration Failures in Steam Quality Sensors for Coating Equipment

March 16, 2025 Admin

Managing Calibration Failures in Steam Quality Sensors for Coating Equipment Managing Calibration Failures in Steam Quality Sensors for Coating Equipment Introduction: In the pharmaceutical industry, maintaining the quality and efficiency of coating equipment is crucial for ensuring the final product’s efficacy and safety. Steam quality sensors play a pivotal role in this process, as they…

Solid Dosage form, Tablets

Troubleshooting Failures in Temperature Mapping for Fluid Bed Dryers

March 15, 2025 Admin

Troubleshooting Failures in Temperature Mapping for Fluid Bed Dryers Troubleshooting Failures in Temperature Mapping for Fluid Bed Dryers Introduction: In the pharmaceutical industry, the drying process is a critical step in the production of solid dosage forms such as tablets. Fluid bed dryers play a significant role in ensuring that the drying process is efficient…

Solid Dosage form, Tablets

Difficulty in ensuring consistent performance of capsule sealing equipment.

March 14, 2025 Admin

Difficulty in ensuring consistent performance of capsule sealing equipment. Difficulty in ensuring consistent performance of capsule sealing equipment. Introduction: In the pharmaceutical industry, the use of capsules as a dosage form is widespread due to their ease of production, patient compliance, and ability to encapsulate a variety of drugs. The capsule sealing process is a…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Residual Binder Issues in Granulation Equipment During Validation

March 14, 2025 Admin

Troubleshooting Residual Binder Issues in Granulation Equipment During Validation Troubleshooting Residual Binder Issues in Granulation Equipment During Validation Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of solid dosage forms like tablets is paramount. Granulation is a critical process in tablet manufacturing, where powders are agglomerated to form granules, enhancing flowability and compressibility…

Solid Dosage form, Tablets

Preventing Granule Breakage During Fluid Bed Drying

March 14, 2025 Admin

Preventing Granule Breakage During Fluid Bed Drying Preventing Granule Breakage During Fluid Bed Drying Introduction: In the pharmaceutical industry, fluid bed drying is a critical process in the production of solid dosage forms, particularly tablets. This method is favored for its efficiency in drying granules, which are the intermediate product before compression into tablets. However,…

Solid Dosage form, Tablets

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets

March 13, 2025 Admin

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Introduction: In the pharmaceutical industry, the coating of tablets plays a crucial role in the product’s performance and patient acceptability. High-speed coating of sugar-coated tablets is a sophisticated process that necessitates precise equipment validation to ensure consistent…

Solid Dosage form, Tablets

Ensuring Adequate Calibration of Equipment in Coating Processes

March 12, 2025 Admin

Ensuring Adequate Calibration of Equipment in Coating Processes Ensuring Adequate Calibration of Equipment in Coating Processes Introduction: In the pharmaceutical industry, the coating of tablets is a critical process that not only enhances the aesthetic appeal of the product but also plays a vital role in controlling the release profile of the active pharmaceutical ingredient…

Solid Dosage form, Tablets

Troubleshooting Residual Powder Issues in Tablet Compression Equipment During Validation

March 10, 2025 Admin

Troubleshooting Residual Powder Issues in Tablet Compression Equipment During Validation Troubleshooting Residual Powder Issues in Tablet Compression Equipment During Validation Introduction: The pharmaceutical industry is continuously evolving, with tablet manufacturing playing a crucial role in the delivery of medications. One of the significant challenges faced during the tablet compression process is the issue of residual…

Solid Dosage form, Tablets