Tag: drying equipment

Poor reproducibility in capsule drying validation results for multi-layer formulations.

April 19, 2025 Admin

Poor reproducibility in capsule drying validation results for multi-layer formulations. Poor reproducibility in capsule drying validation results for multi-layer formulations. Introduction: The pharmaceutical industry continuously strives to enhance the quality and efficacy of solid oral dosage forms, including capsules. Among these, multi-layer formulations have gained popularity due to their ability to deliver complex dosing regimens…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring consistent capsule drying times.

April 15, 2025 Admin

Difficulty in ensuring consistent capsule drying times. Difficulty in Ensuring Consistent Capsule Drying Times Introduction: The pharmaceutical industry heavily relies on solid oral dosage forms like capsules due to their convenience, stability, and patient compliance. However, achieving consistent drying times for capsules, particularly hard and soft gelatin types, is critical yet challenging. The drying process…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in capsule drying validation for high-oil formulations.

April 12, 2025 Admin

Poor reproducibility in capsule drying validation for high-oil formulations. Poor reproducibility in capsule drying validation for high-oil formulations. Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms, such as capsules, is paramount. Among the various challenges faced during capsule production, drying validation in high-oil formulations stands out due to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with validating capsule drying processes for low-humidity environments.

April 11, 2025 Admin

Problems with validating capsule drying processes for low-humidity environments. Problems with validating capsule drying processes for low-humidity environments. Introduction: In the realm of pharmaceutical manufacturing, capsules serve as one of the most popular solid oral dosage forms due to their versatility and patient compliance. However, the process of drying capsules, particularly in low-humidity environments, presents…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating capsule drying equipment for dual-layer formulations.

April 6, 2025 Admin

Challenges in validating capsule drying equipment for dual-layer formulations. Challenges in validating capsule drying equipment for dual-layer formulations. Introduction: In the realm of pharmaceutical manufacturing, the development and validation of dual-layer formulations present unique challenges, particularly in the drying stage of capsule production. The drying process is critical to ensuring the stability, efficacy, and safety…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Heat Damage in API Granules During Drying Validation

April 3, 2025 Admin

Troubleshooting Heat Damage in API Granules During Drying Validation Troubleshooting Heat Damage in API Granules During Drying Validation Introduction: In the pharmaceutical industry, the drying process of Active Pharmaceutical Ingredient (API) granules is a critical step in the production of solid dosage forms such as tablets. Ensuring the stability and integrity of APIs during drying…

Solid Dosage form, Tablets

Difficulty in validating capsule drying processes for thermosensitive APIs.

April 1, 2025 Admin

Difficulty in validating capsule drying processes for thermosensitive APIs. Difficulty in validating capsule drying processes for thermosensitive APIs Introduction: In the realm of pharmaceutical manufacturing, ensuring the stability and efficacy of Active Pharmaceutical Ingredients (APIs) is paramount. Thermosensitive APIs, which are prone to degradation at elevated temperatures, pose unique challenges. As capsules, especially hard and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating capsule drying processes for multi-dose formulations.

March 5, 2025 Admin

Challenges in validating capsule drying processes for multi-dose formulations. Challenges in validating capsule drying processes for multi-dose formulations. Introduction: In the pharmaceutical industry, the validation of capsule drying processes for multi-dose formulations is a critical component in ensuring the quality and efficacy of the final product. As capsules are widely used due to their versatility…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Heat Sensitivity Issues During Fluid Bed Drying

March 5, 2025 Admin

Troubleshooting Heat Sensitivity Issues During Fluid Bed Drying Troubleshooting Heat Sensitivity Issues During Fluid Bed Drying Introduction: Fluid bed drying is a widely used method in pharmaceutical manufacturing for drying granules and powders before tablet compression. This process ensures uniform drying and improved product quality. However, the challenge of heat sensitivity in certain pharmaceutical compounds…

Solid Dosage form, Tablets