Tag: Drug stability

Preventing Color Fading in Sugar-Coated Tablets During Packaging

June 1, 2025 Admin

Preventing Color Fading in Sugar-Coated Tablets During Packaging Preventing Color Fading in Sugar-Coated Tablets During Packaging Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, providing an effective way to mask the taste of medication while enhancing its aesthetic appeal. However, maintaining the vibrant color of these tablets during packaging and storage is…

Solid Dosage form, Tablets

Ensuring Consistent Release Profiles in Multi-API Tablets Over Time

May 27, 2025 Admin

Ensuring Consistent Release Profiles in Multi-API Tablets Over Time Ensuring Consistent Release Profiles in Multi-API Tablets Over Time Introduction: In the pharmaceutical industry, the formulation and manufacturing of multi-API (Active Pharmaceutical Ingredient) tablets present a complex challenge. Ensuring consistent drug release profiles over time is crucial for therapeutic efficacy and patient safety. A consistent release…

Solid Dosage form, Tablets

Resolving Brittleness in Immediate Release Tablets During Long-Term Storage

May 26, 2025 Admin

Resolving Brittleness in Immediate Release Tablets During Long-Term Storage Resolving Brittleness in Immediate Release Tablets During Long-Term Storage Introduction: Immediate release tablets are a cornerstone of pharmaceutical dosage forms, designed to disintegrate promptly after administration to ensure rapid drug release. However, maintaining their integrity during long-term storage poses significant challenges. One of the most critical…

Solid Dosage form, Tablets

Evaluating Interaction Between Packaging and Tablets in Stability Testing

May 21, 2025 Admin

Evaluating Interaction Between Packaging and Tablets in Stability Testing Evaluating Interaction Between Packaging and Tablets in Stability Testing Introduction: In the pharmaceutical industry, the stability of a drug product is a critical factor that determines its safety, efficacy, and shelf life. Solid dosage forms, like tablets, are particularly sensitive to environmental factors such as humidity,…

Solid Dosage form, Tablets

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging

May 18, 2025 Admin

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Introduction: Sugar-coated tablets have been a mainstay in pharmaceutical formulations for decades. Their aesthetic appeal, taste masking, and ability to protect the active pharmaceutical ingredient (API) are among their numerous advantages. However, the hygroscopic nature of sugar poses a…

Solid Dosage form, Tablets

Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions

May 18, 2025 Admin

Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions Managing Layer Separation in Bilayer Tablets Under Accelerated Conditions Introduction: Bilayer tablets are increasingly utilized in the pharmaceutical industry to deliver multiple drugs or different release profiles in a single dosage form. This innovative approach not only enhances patient compliance but also offers significant benefits in…

Solid Dosage form, Tablets

Ensuring Adequate Process Controls for Hygroscopic Tablet Production

May 14, 2025 Admin

Ensuring Adequate Process Controls for Hygroscopic Tablet Production Ensuring Adequate Process Controls for Hygroscopic Tablet Production Introduction: Hygroscopic tablets, known for their ability to absorb moisture from the environment, pose unique challenges in pharmaceutical manufacturing. Ensuring adequate process controls during their production is crucial for maintaining product stability, efficacy, and quality. This comprehensive guide delves…

Solid Dosage form, Tablets

Investigating Solvent Evaporation Effects on Coated Tablets During Storage

May 13, 2025 Admin

Investigating Solvent Evaporation Effects on Coated Tablets During Storage Investigating Solvent Evaporation Effects on Coated Tablets During Storage Introduction: In the pharmaceutical industry, the stability and integrity of coated tablets during storage are paramount to ensuring their efficacy and safety. Solvent evaporation is a critical factor that can affect the coating’s performance, leading to potential…

Solid Dosage form, Tablets

Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets

May 12, 2025 Admin

Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Introduction: Enteric-coated tablets are a critical part of modern pharmacology, designed to protect active ingredients from the acidic environment of the stomach and ensure release in the more neutral pH of the intestine. This targeted delivery system…

Solid Dosage form, Tablets

Managing API Migration in Multi-API Tablets During Stability Testing

May 11, 2025 Admin

Managing API Migration in Multi-API Tablets During Stability Testing Managing API Migration in Multi-API Tablets During Stability Testing Introduction: In the ever-evolving world of pharmaceuticals, the development of multi-active pharmaceutical ingredient (API) tablets has gained significant momentum. These formulations offer the advantage of delivering multiple therapeutic effects in a single dose, enhancing patient compliance and…

Solid Dosage form, Tablets

Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements

May 4, 2025 Admin

Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of tablets throughout their shelf life is paramount. This is particularly critical for tablets with extended stability requirements. The compatibility between the packaging and the tablet formulation…

Solid Dosage form, Tablets

Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time

May 3, 2025 Admin

Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time Introduction: Extended release tablets are a crucial aspect of modern pharmaceutical delivery systems, offering consistent therapeutic effects over extended periods. However, the integrity of their coating is paramount to ensure proper drug release and efficacy….

Solid Dosage form, Tablets